Copper gluconate

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Name
Copper gluconate
Accession Number
DB11246
Type
Small Molecule
Groups
Approved, Investigational
Description

Copper gluconate is a copper salt of D-gluconic acid that displays a light blue to bluish-green color. It is prepared by the reaction of gluconic acid solutions with cupric oxide or basic cupric carbonate. According to the good manufacturing or feeding practice by the FDA, copper gluconate is used as a nutrient or dietary supplement and is generally recognized as safe for use at a level not exceeding 0.005 percent.

Structure
Thumb
Synonyms
Not Available
Active Moieties
NameKindUNIICASInChI Key
Copperunknown789U1901C57440-50-8RYGMFSIKBFXOCR-UHFFFAOYSA-N
Cupric cationionicFV4Y0JO2CX15158-11-9JPVYNHNXODAKFH-UHFFFAOYSA-N
Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing End
Flexadyn TabCopper gluconate (.1 mg) + Cyanocobalamin (100 mcg) + Magnesium carbonate (100 mg) + Potassium gluconate (50 mg) + Pyridoxine hydrochloride (50 mg) + Vitamin A (1000 unit)TabletOralNutri Dyn Products Ltd.1976-12-311996-09-09Canada
Iron, Vit & Min SuppCopper gluconate (1 mg) + Choline bitartrate (82 mg) + Cyanocobalamin (14 mcg) + D-alpha-Tocopherol acetate (10 unit) + Ferric ammonium citrate (30 mg) + Folic Acid (.1 mg) + Niacin (2.5 mg) + Nicotinamide (7.5 mg) + Pantothenic acid (5 mg) + Pyridoxine (1.5 mg) + Riboflavin (1.2 mg) + Thiamine (1 mg)TabletOralAvacare, Division Of Jeunique International Inc.1985-12-311996-09-09Canada
Prenatal Chelated MineralCopper gluconate (0.5 mg/1) + Calcium Carbonate (30 mg/1) + Calcium citrate tetrahydrate (32.5 mg/1) + Ferrous fumarate (7 mg/1) + Magnesium citrate (75 mg/1) + Potassium Iodide (75 ug/1) + Zinc citrate (5 mg/1)TabletOralUsana Health Sciences, Inc.2012-04-11Not applicableUs
Unapproved/Other Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing End
Tricare Prenatal 2-part Daily Prenatal Vitamin SystemCopper gluconate (1 mg/1) + Ascorbic acid (30 mg/1) + Biotin (.150 mg/1) + Cholecalciferol (400 [iU]/1) + Chromium Cr-51 chloride (.060 mg/1) + Cyanocobalamin (.125 mg/1) + Doconexent (150 1/1) + Ferric pyrophosphate (4.5 mg/1) + Icosapent (37.5 1/1) + Levomefolic acid (1 mg/1) + Manganese citrate decahydrate (1 mg/1) + Nicotinamide (10 mg/1) + Omega-3 fatty acids (75 1/1) + Calcium pantothenate (5 mg/1) + Pyridoxine hydrochloride (2.5 mg/1) + Riboflavin (.85 mg/1) + Sodium selenite (.0325 mg/1) + Sodium molybdate (.0375 mg/1) + Thiamine mononitrate (1.25 mg/1) + Zinc (7 mg/1) + alpha-Tocopherol succinate (15 [iU]/1)KitMedecor Pharma, Llc2016-05-10Not applicableUs
Vp-heme ObCopper gluconate (0.8 mg/1) + Biotin (30 ug/1) + Cholecalciferol (400 [iU]/1) + Cyanocobalamin (12 ug/1) + Folic Acid (1 mg/1) + Heme iron polypeptide (6 mg/1) + Iron saccharate (28 mg/1) + Nicotinamide (17 mg/1) + Calcium pantothenate (10 mg/1) + Potassium Iodide (250 ug/1) + Pyridoxine hydrochloride (50 mg/1) + Riboflavin (1.6 mg/1) + Sodium selenate (65 mg/1) + Thiamine mononitrate (1.5 mg/1) + Zinc oxide (4.5 mg/1) + alpha-Tocopherol succinate (10 [iU]/1)Tablet, film coatedOralVirtus Pharmaceuticals2013-10-142016-05-31Us
Categories
UNII
RV823G6G67
CAS number
527-09-3
Weight
Average: 453.841
Monoisotopic: 453.030556491
Chemical Formula
C12H22CuO14
InChI Key
OCUCCJIRFHNWBP-IYEMJOQQSA-L
InChI
InChI=1S/2C6H12O7.Cu/c2*7-1-2(8)3(9)4(10)5(11)6(12)13;/h2*2-5,7-11H,1H2,(H,12,13);/q;;+2/p-2/t2*2-,3-,4+,5-;/m11./s1
IUPAC Name
copper(2+) ion bis((2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoate)
SMILES
[Cu++].OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O

Pharmacology

Indication
Not Available
Pharmacodynamics
Not Available
Mechanism of action
Not Available
Absorption
Not Available
Volume of distribution
Not Available
Protein binding
Not Available
Metabolism
Not Available
Route of elimination
Not Available
Half life
Not Available
Clearance
Not Available
Toxicity
Not Available
Affected organisms
Not Available
Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
Not Available
Food Interactions
Not Available

References

General References
Not Available
External Links
KEGG Compound
C12278
PubChem Compound
10692
PubChem Substance
347827950
ChemSpider
10242
ChEBI
31431
Wikipedia
Copper_gluconate

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
1CompletedTreatmentMalignancies1
1RecruitingTreatmentProstate Cancer1
1, 2SuspendedTreatmentGlioblastoma Multiforme (GBM)1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage forms
FormRouteStrength
TabletOral
Kit
Tablet, film coatedOral
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility37.9 mg/mLALOGPS
logP-2ALOGPS
logP-3.4ChemAxon
logS-1.1ALOGPS
pKa (Strongest Acidic)3.39ChemAxon
pKa (Strongest Basic)-3ChemAxon
Physiological Charge-1ChemAxon
Hydrogen Acceptor Count7ChemAxon
Hydrogen Donor Count5ChemAxon
Polar Surface Area141.28 Å2ChemAxon
Rotatable Bond Count10ChemAxon
Refractivity49.11 m3·mol-1ChemAxon
Polarizability16.62 Å3ChemAxon
Number of Rings0ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterNoChemAxon
Veber's RuleNoChemAxon
MDDR-like RuleNoChemAxon
Predicted ADMET features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Not Available

Taxonomy

Description
This compound belongs to the class of organic compounds known as sugar acids and derivatives. These are compounds containing a saccharide unit which bears a carboxylic acid group.
Kingdom
Organic compounds
Super Class
Organic oxygen compounds
Class
Organooxygen compounds
Sub Class
Carbohydrates and carbohydrate conjugates
Direct Parent
Sugar acids and derivatives
Alternative Parents
Medium-chain hydroxy acids and derivatives / Medium-chain fatty acids / Beta hydroxy acids and derivatives / Hydroxy fatty acids / Monosaccharides / Secondary alcohols / Carboxylic acid salts / Polyols / Carboxylic acids / Monocarboxylic acids and derivatives
show 6 more
Substituents
Gluconic_acid / Medium-chain hydroxy acid / Medium-chain fatty acid / Beta-hydroxy acid / Hydroxy fatty acid / Hydroxy acid / Fatty acyl / Fatty acid / Monosaccharide / Carboxylic acid salt
show 15 more
Molecular Framework
Not Available
External Descriptors
organic molecular entity (CHEBI:31431)

Drug created on December 03, 2015 09:51 / Updated on November 02, 2018 07:08