Poloxamer 407

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

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Name
Poloxamer 407
Accession Number
DB11252
Type
Small Molecule
Groups
Approved, Investigational
Description

Poloxamer 407 is a polyoxyethylene polymer and hydrophilic non-ionic surfactant. It consists of a central hydrophobic block of polypropylene glycol that is flanked on each side by polyethylene glycol blocks, both hydrophilic in nature. Poloxamer 407 is used as an emulsifying agent and solubilizing agent in cosmetic and personal products such as contact lens cleaning solutions.

Synonyms
Not Available
Over the Counter Products
NameDosageStrengthRouteLabellerMarketing StartMarketing End
Dream EyeLiquid0.1 mL/1mLOphthalmicK&J.C Co., Ltd2010-10-13Not applicableUs
Dream EyeLiquid0.1 mL/1mLOphthalmicK&J.C Co., Ltd2010-06-17Not applicableUs
Natural CareLiquid0.1 mL/1mLOphthalmicK&J.C Co., Ltd2010-10-05Not applicableUs
Additional Data Available
  • Application Number
    Application Number

    A unique ID assigned by the FDA when a product is submitted for approval by the labeller.

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  • Product Code
    Product Code

    A governmentally-recognized ID which uniquely identifies the product within its regulatory market.

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Unapproved/Other Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing End
Dream EyePoloxamer 407 (0.1 mL/1mL)LiquidOphthalmicK&J.C Co., Ltd2010-10-13Not applicableUs
Dream EyePoloxamer 407 (0.1 mL/1mL)LiquidOphthalmicK&J.C Co., Ltd2010-06-17Not applicableUs
Natural CarePoloxamer 407 (0.1 mL/1mL)LiquidOphthalmicK&J.C Co., Ltd2010-10-05Not applicableUs
Categories
UNII
TUF2IVW3M2
CAS number
Not Available
Weight
Not Available
Chemical Formula
Not Available
InChI Key
Not Available
InChI
Not Available
IUPAC Name
Not Available
SMILES
Not Available

Pharmacology

Indication
Not Available
Pharmacodynamics
Not Available
Mechanism of action
Not Available
Additional Data Available
Adverse Effects

Comprehensive structured data on known drug adverse effects with statistical prevalence. MedDRA and ICD10 ids are provided for adverse effect conditions and symptoms.

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Additional Data Available
Contraindications

Structured data covering drug contraindications. Each contraindication describes a scenario in which the drug is not to be used. Includes restrictions on co-administration, contraindicated populations, and more.

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Additional Data Available
Blackbox Warnings

Structured data representing warnings from the black box section of drug labels. These warnings cover important and dangerous risks, contraindications, or adverse effects.

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Absorption
Not Available
Volume of distribution
Not Available
Protein binding
Not Available
Metabolism
Not Available
Route of elimination
Not Available
Half life
Not Available
Clearance
Not Available
Toxicity
Not Available
Affected organisms
Not Available
Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
Not Available
Food Interactions
Not Available

References

General References
Not Available
External Links
PubChem Substance
347911166
Wikipedia
Poloxamer_407

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
2CompletedSupportive CareOral Mucositis1
2TerminatedTreatmentPersistent Corneal Epithelial Defects1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage forms
FormRouteStrength
LiquidOphthalmic0.1 mL/1mL
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
Not Available
Predicted ADMET features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Not Available

Taxonomy

Classification
Not classified

Drug created on December 03, 2015 09:51 / Updated on June 04, 2019 07:18