Brilliant green

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Name
Brilliant green cation
Commonly known or available as Brilliant green
Accession Number
DB11279
Description

Brilliant green, or ethanaminium, is a derivative of triarylmethane dye that has been used as a dye to color silk and wool. Due to its inhibitory actions against Gram positive microorganisms, brilliant green can be found in antiseptic products such as solutions and swabs used to prevent infection.

Type
Small Molecule
Groups
Approved, Vet approved
Structure
Thumb
Weight
Average: 385.574
Monoisotopic: 385.263825491
Chemical Formula
C27H33N2
Synonyms
  • Brilliant green ion
  • Brilliant green, free form
  • Brilliant green(1+)
External IDs
  • NSC-5011

Pharmacology

Indication
Not Available
Contraindications & Blackbox Warnings
Learn about our commercial Contraindications & Blackbox Warnings data.
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Pharmacodynamics
Not Available
Mechanism of action
Not Available
Absorption
Not Available
Volume of distribution
Not Available
Protein binding
Not Available
Metabolism
Not Available
Route of elimination
Not Available
Half-life
Not Available
Clearance
Not Available
Adverse Effects
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Toxicity
Not Available
Affected organisms
Not Available
Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
No interactions found.

Products

Product Ingredients
IngredientUNIICASInChI Key
Brilliant greenG0L543D370633-03-4NNBFNNNWANBMTI-UHFFFAOYSA-M
Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
Kerr 100 Triple Dye Dispos-ABrilliant green (2.29 mg/1mL) + Gentian violet (2.2 mg/1mL) + Proflavine hemisulfate (1.14 mg/1mL)SwabTopicalVistapharm, Inc.2004-05-01Not applicableUs
Perineze Triple DyeBrilliant green (2.29 mg/0.61mL) + Gentian violet (2.29 mg/0.61mL) + Proflavine hemisulfate (1.14 mg/0.61mL)SolutionTopicalPeace Medical Inc.2011-09-28Not applicableUs
Triple DyeBrilliant green (2.29 mg) + Gentian violet (2.29 mg) + Proflavine hemisulfate (1.14 mg)LiquidTopicalFrank W. Kerr Chemical Company1983-12-312004-10-27Canada

Categories

Drug Categories
Classification
Not classified

Chemical Identifiers

UNII
S85JD8CLBH
CAS number
18198-35-1
InChI Key
HXCILVUBKWANLN-UHFFFAOYSA-N
InChI
InChI=1S/C27H33N2/c1-5-28(6-2)25-18-14-23(15-19-25)27(22-12-10-9-11-13-22)24-16-20-26(21-17-24)29(7-3)8-4/h9-21H,5-8H2,1-4H3/q+1
IUPAC Name
4-{[4-(diethylamino)phenyl](phenyl)methylidene}-N,N-diethylcyclohexa-2,5-dien-1-iminium
SMILES
CCN(CC)C1=CC=C(C=C1)C(C1=CC=CC=C1)=C1C=CC(C=C1)=[N+](CC)CC

References

General References
Not Available
PubChem Compound
12449
PubChem Substance
347827961
ChemSpider
11942
BindingDB
81263
RxNav
1546367
ChEBI
88176
ChEMBL
CHEMBL1589793
ZINC
ZINC000004235575
Wikipedia
Brilliant_Green

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
SwabTopical
SolutionTopical
LiquidTopical
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility0.0003 mg/mLALOGPS
logP2.47ALOGPS
logP2.71ChemAxon
logS-6.2ALOGPS
pKa (Strongest Basic)5.36ChemAxon
Physiological Charge1ChemAxon
Hydrogen Acceptor Count1ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area6.25 Å2ChemAxon
Rotatable Bond Count7ChemAxon
Refractivity150.57 m3·mol-1ChemAxon
Polarizability47.39 Å3ChemAxon
Number of Rings3ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterNoChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleYesChemAxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Not Available

Drug created on December 03, 2015 09:52 / Updated on June 12, 2020 10:53

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