Borneol

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name
Borneol
DrugBank Accession Number
DB11288
Background

Not Available

Type
Small Molecule
Groups
Experimental
Structure
Weight
Average: 154.2493
Monoisotopic: 154.135765198
Chemical Formula
C10H18O
Synonyms
  • Borneo camphor
  • Bornyl alcohol
  • endo-1,7,7-trimethylbicyclo[2.2.1]heptan-2-ol
  • endo-2-bornanol
  • endo-2-camphanol
  • endo-2-hydroxycamphane
  • Sumatra camphor

Pharmacology

Indication

Not Available

Reduce drug development failure rates
Build, train, & validate machine-learning models
with evidence-based and structured datasets.
See how
Build, train, & validate predictive machine-learning models with structured datasets.
See how
Associated Conditions
Indication TypeIndicationCombined Product DetailsApproval LevelAge GroupPatient CharacteristicsDose Form
Used in combination for symptomatic treatment ofArthritisCombination Product in combination with: Methyl salicylate (DB09543), Camphor (DB01744), Thymol (DB02513), Levomenthol (DB00825)••• ••••••••••
Used in combination to treatBackacheCombination Product in combination with: Levomenthol (DB00825), Camphor (DB01744), Thymol (DB02513), Methyl salicylate (DB09543)••• ••••••••••
Used in combination to treatBruisesCombination Product in combination with: Camphor (DB01744), Methyl salicylate (DB09543), Thymol (DB02513), Levomenthol (DB00825)••• ••••••••••
Used as adjunct in combination to treatDiabetesCombination Product in combination with: Eucalyptol (DB03852), Menthone (DB15920), Camphene (DB15917), Levomenthol (DB00825), alpha-Pinene (DB15573), beta-Pinene (DB15574)•••••••••••••••••••
Used in combination to treatGallbladder disordersCombination Product in combination with: Levomenthol (DB00825), alpha-Pinene (DB15573), beta-Pinene (DB15574), Camphene (DB15917), Menthone (DB15920), Eucalyptol (DB03852)•••••••••••••••••••
Contraindications & Blackbox Warnings
Prevent Adverse Drug Events Today
Tap into our Clinical API for life-saving information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.
Learn more
Avoid life-threatening adverse drug events with our Clinical API
Learn more
Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
Improve decision support & research outcomes
With structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!
See the data
Improve decision support & research outcomes with our structured adverse effects data.
See a data sample
Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Products

Drug product information from 10+ global regions
Our datasets provide approved product information including:
dosage, form, labeller, route of administration, and marketing period.
Access now
Access drug product information from over 10 global regions.
Access now
Over the Counter Products
NameDosageStrengthRouteLabellerMarketing StartMarketing EndRegionImage
CreamCream3 g/20gCutaneousShantou Youjia E-Commerce Co., Ltd.2024-02-012024-12-31US flag
Enokon Pain relief patchPatch1 g/1001TopicalHenan Enokon Medical Instrument Co Ltd.2023-06-28Not applicableUS flag
Enokon Pain relief patch-acupoint pressure stimulationPatch1 g/1001TopicalHenan Enokon Medical Instrument Co Ltd.2023-01-06Not applicableUS flag
Tendon Sheath PatchPatch15 g/1001TopicalGuangzhou Hanhai Trading Co., Ltd2023-09-19Not applicableUS flag
Varicose Veins PatchPatch12 g/1001TopicalGuangzhou Hanhai Trading Co., Ltd2023-09-12Not applicableUS flag
Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
Hundred Koyok ClassicBorneol (0.18 mg) + Camphor (0.41 mg) + Levomenthol (0.62 mg) + Methyl salicylate (0.62 mg) + Thymol (0.04 mg)PlasterTransdermalJWP Medical Sdn. Bhd.2020-09-08Not applicableMalaysia flag
HundredPlast KoyokBorneol (0.18 mg) + Camphor (0.41 mg) + Levomenthol (0.62 mg) + Methyl salicylate (0.62 mg) + Thymol (0.04 mg)PatchTopicalTEONG HUAT MEDICAL SDN. BHD.2020-09-08Not applicableMalaysia flag
HUNDREDPLAST KOYOK CLASSICBorneol (1.5 %w/w) + Camphor (3 %w/w) + Levomenthol (6.5 %w/w) + Methyl salicylate (6.5 %w/w) + Thymol (0.5 %w/w)PlasterTransdermalTHP MEDICAL SDN. BHD.2020-09-08Not applicableMalaysia flag
Kwan Tak Hing Plaster - Pad-plsBorneol (1.75 g / pad) + Levomenthol (3.5 g / pad)Plaster; SwabTopicalWing Quon Enterprises Ltd.1996-08-161998-08-12Canada flag
La Jiao Feng Shi GaoBorneol (3.0 g/100g) + Levomenthol (3.0 g/100g)PlasterTransdermalHenan Lingrui Pharmaceutical Co.; Ltd2010-06-022014-03-11US flag
Unapproved/Other Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
Ma Ying Long HemorrhoidalBorneol (0.2 g/10g) + Amber (0.1 g/10g) + Bos taurus gallstone (0.1 g/10g) + Moschus berezovskii musk sac resin (0.15 g/10g) + Pearl (hyriopsis cumingii) (0.25 g/10g) + Sodium borate decahydrate (0.2 g/10g) + Zinc carbonate (0.65 g/10g)OintmentTopicalTrifecta Pharmaceuticals Usa, Llc.2016-01-14Not applicableUS flag
Tendon Sheath PatchBorneol (15 g/1001)PatchTopicalGuangzhou Hanhai Trading Co., Ltd2023-09-19Not applicableUS flag

Categories

Drug Categories
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
M89NIB437X
CAS number
507-70-0
InChI Key
DTGKSKDOIYIVQL-UHFFFAOYSA-N
InChI
InChI=1S/C10H18O/c1-9(2)7-4-5-10(9,3)8(11)6-7/h7-8,11H,4-6H2,1-3H3
IUPAC Name
1,7,7-trimethylbicyclo[2.2.1]heptan-2-ol
SMILES
CC1(C)C2CCC1(C)C(O)C2

References

General References
Not Available
KEGG Compound
C01411
ChemSpider
58234
RxNav
1368202
ChEBI
28093
ChEMBL
CHEMBL1097205
Wikipedia
Borneol

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
2CompletedTreatmentAllergic Rhinitis (AR) / Nasal Lavage / Traditional Chinese Medicine1
1Unknown StatusTreatmentIntracranial Hemorrhages / Stroke, Acute1
0CompletedTreatmentChronic Stable Angina Pectoris1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
CreamCutaneous3 g/20g
PatchTopical1 g/1001
PatchTopical
Plaster; swabTopical
PlasterTransdermal
OintmentTopical
DressingCutaneous
CapsuleOral
PlasterTopical
SprayTopical
Plaster
PatchTopical15 g/1001
Capsule, gelatin coatedOral
PatchTopical12 g/1001
Ointment
LiquidDental
SolutionOral
Capsule
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility0.805 mg/mLALOGPS
logP2.83ALOGPS
logP1.99Chemaxon
logS-2.3ALOGPS
pKa (Strongest Acidic)19.6Chemaxon
pKa (Strongest Basic)-0.78Chemaxon
Physiological Charge0Chemaxon
Hydrogen Acceptor Count1Chemaxon
Hydrogen Donor Count1Chemaxon
Polar Surface Area20.23 Å2Chemaxon
Rotatable Bond Count0Chemaxon
Refractivity45.31 m3·mol-1Chemaxon
Polarizability18.48 Å3Chemaxon
Number of Rings2Chemaxon
Bioavailability1Chemaxon
Rule of FiveYesChemaxon
Ghose FilterNoChemaxon
Veber's RuleYesChemaxon
MDDR-like RuleNoChemaxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
SpectrumSpectrum TypeSplash Key
Mass Spectrum (Electron Ionization)MSsplash10-0002-9200000000-66036eb28e5b6b9f86e6
Predicted MS/MS Spectrum - 10V, Positive (Annotated)Predicted LC-MS/MSsplash10-08fr-6900000000-b9cfff5981d0b2d4d4a7
Predicted MS/MS Spectrum - 10V, Negative (Annotated)Predicted LC-MS/MSsplash10-0udi-0900000000-be9bc5a8122a18286be5
Predicted MS/MS Spectrum - 20V, Positive (Annotated)Predicted LC-MS/MSsplash10-02ai-9200000000-6cc99dd46f1a8a932b85
Predicted MS/MS Spectrum - 20V, Negative (Annotated)Predicted LC-MS/MSsplash10-0udi-0900000000-347a0faa19ac3e588a8c
Predicted MS/MS Spectrum - 40V, Positive (Annotated)Predicted LC-MS/MSsplash10-00kf-9000000000-2e907c2cdc4885534e8b
Predicted MS/MS Spectrum - 40V, Negative (Annotated)Predicted LC-MS/MSsplash10-0udi-0900000000-9be9b49076b221a10202
Predicted 1H NMR Spectrum1D NMRNot Applicable
Predicted 13C NMR Spectrum1D NMRNot Applicable
Chromatographic Properties
Collision Cross Sections (CCS)
AdductCCS Value (Å2)Source typeSource
[M-H]-140.85579
predicted
DeepCCS 1.0 (2019)
[M+H]+143.25136
predicted
DeepCCS 1.0 (2019)
[M+Na]+150.63554
predicted
DeepCCS 1.0 (2019)

Drug created at December 03, 2015 16:52 / Updated at June 12, 2020 16:53