Showing BioInteractions for Thrombin (DB11300)
BioInteractor utilizes data on drug-target, -enzyme and -transporter associations to provide insight on drug-drug interactions. It allows you to identify, for instance, which drugs act similarly on the same target. Such drugs may have additive pharmacodynamic effects if given concomitantly. Conversely, two drugs may antagonize the beneficial effects of each other by having opposite actions on a specific drug target. BioInteractor uses ranked drug-enzyme association information to predict enzyme-mediated drug interactions that may be clinically relevant.
Interacting Group | Interacting Drugs | |
---|---|---|
Thrombin is a Coagulation factor XI activator | ||
1 | Coagulation factor XI ligands | Coagulation Factor IX (Recombinant), Coagulation Factor IX Human |
2 | Coagulation factor XI inhibitors | Conestat alfa, Human C1-esterase inhibitor |
3 | Coagulation factor XI activators | Human thrombin, Zinc chloride, Zinc sulfate, unspecified form |
Interacting Group | Interacting Drugs | |
---|---|---|
Thrombin is a Coagulation factor XIII A chain activator | ||
1 | Coagulation factor XIII A chain substrates | L-Glutamine |
2 | Coagulation factor XIII A chain agonists | Anti-inhibitor coagulant complex, Prothrombin |
3 | Coagulation factor XIII A chain activators | Human thrombin |
Interacting Group | Interacting Drugs | |
---|---|---|
Thrombin is a Coagulation factor XIII B chain activator | ||
1 | Coagulation factor XIII B chain activators | Human thrombin |
Interacting Group | Interacting Drugs | |
---|---|---|
Thrombin is a Fibrinogen alpha chain activator | ||
1 | Fibrinogen alpha chain activators | Human thrombin, Thrombin alfa |
2 | Fibrinogen alpha chain binders | Zinc chloride, Zinc sulfate, unspecified form |
Interacting Group | Interacting Drugs | |
---|---|---|
Thrombin is a Fibrinogen beta chain activator | ||
1 | Fibrinogen beta chain activators | Human thrombin, Thrombin alfa |
Interacting Group | Interacting Drugs | |
---|---|---|
Thrombin is a Fibrinogen gamma chain activator | ||
1 | Fibrinogen gamma chain activators | Human thrombin, Thrombin alfa |
Interacting Group | Interacting Drugs | |
---|---|---|
Thrombin is a Coagulation factor V activator | ||
1 | Coagulation factor V binders | Copper |
2 | Coagulation factor V antagonists | Protein S human |
3 | Coagulation factor V agonists | Anti-inhibitor coagulant complex |
4 | Coagulation factor V substrates | Anti-inhibitor coagulant complex |
5 | Coagulation factor V activators | Human thrombin, Thrombin alfa |
6 | Coagulation factor V inactivators | Protein C |
Interacting Group | Interacting Drugs | |
---|---|---|
Thrombin is a Coagulation factor VIII activator | ||
1 | Coagulation factor VIII cofactors | Coagulation Factor IX (Recombinant), Coagulation Factor IX Human, Nonacog beta pegol |
2 | Coagulation factor VIII binders | Copper, Damoctocog alfa pegol |
3 | Coagulation factor VIII agonists | Anti-inhibitor coagulant complex |
4 | Coagulation factor VIII substrates | Albutrepenonacog alfa, Anti-inhibitor coagulant complex |
5 | Coagulation factor VIII activators | Human thrombin, Thrombin alfa |
6 | Coagulation factor VIII inactivators | Protein C |