Kinetin

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Name
Kinetin
Accession Number
DB11336
Type
Small Molecule
Groups
Approved
Description

Kinetin is a cytokinin which are plant hormones promotes cell division and plant growth. It was shown to naturally exist in DNA of organisms including humans and various plants. While kinetin is used in tissue cultures to produce new plants, it is also found in cosmetic products as an anti-aging agents.

Structure
Thumb
Synonyms
Not Available
Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing End
ObagiGentle Rejuvenati Gentle RejuvenationKinetin (.03 mg/30g) + Zeatin (.03 mg/30g)LotionTopicalYS PLUS CORPORATION2014-10-012015-12-31Us
Categories
UNII
P39Y9652YJ
CAS number
525-79-1
Weight
Average: 215.2114
Monoisotopic: 215.080709935
Chemical Formula
C10H9N5O
InChI Key
QANMHLXAZMSUEX-UHFFFAOYSA-N
InChI
InChI=1S/C10H9N5O/c1-2-7(16-3-1)4-11-9-8-10(13-5-12-8)15-6-14-9/h1-3,5-6H,4H2,(H2,11,12,13,14,15)
IUPAC Name
N-(furan-2-ylmethyl)-7H-purin-6-amine
SMILES
C(NC1=NC=NC2=C1NC=N2)C1=CC=CO1

Pharmacology

Indication
Not Available
Pharmacodynamics
Not Available
Mechanism of action
Not Available
Absorption
Not Available
Volume of distribution
Not Available
Protein binding
Not Available
Metabolism
Not Available
Route of elimination
Not Available
Half life
Not Available
Clearance
Not Available
Toxicity
Not Available
Affected organisms
Not Available
Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
Not Available
Food Interactions
Not Available

References

General References
  1. Chiu PC, Chan CC, Lin HM, Chiu HC: The clinical anti-aging effects of topical kinetin and niacinamide in Asians: a randomized, double-blind, placebo-controlled, split-face comparative trial. J Cosmet Dermatol. 2007 Dec;6(4):243-9. [PubMed:18047609]
External Links
Human Metabolome Database
HMDB0012245
KEGG Compound
C08272
PubChem Compound
3830
PubChem Substance
347827968
ChemSpider
3698
BindingDB
181147
ChEBI
27407
ChEMBL
CHEMBL228792
HET
H35
Wikipedia
Kinetin
PDB Entries
2uy5 / 3o5w / 3t4s / 4a85 / 4a86 / 4jhh / 4jkx

Clinical Trials

Clinical Trials
Not Available

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage forms
FormRouteStrength
LotionTopical
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility0.94 mg/mLALOGPS
logP0.96ALOGPS
logP0.51ChemAxon
logS-2.4ALOGPS
pKa (Strongest Acidic)10.2ChemAxon
pKa (Strongest Basic)5.16ChemAxon
Physiological Charge0ChemAxon
Hydrogen Acceptor Count4ChemAxon
Hydrogen Donor Count2ChemAxon
Polar Surface Area79.63 Å2ChemAxon
Rotatable Bond Count3ChemAxon
Refractivity60.72 m3·mol-1ChemAxon
Polarizability21.33 Å3ChemAxon
Number of Rings3ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleNoChemAxon
MDDR-like RuleNoChemAxon
Predicted ADMET features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
SpectrumSpectrum TypeSplash Key
Predicted GC-MS Spectrum - GC-MSPredicted GC-MSNot Available
Predicted MS/MS Spectrum - 10V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 20V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 40V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 10V, Negative (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 20V, Negative (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 40V, Negative (Annotated)Predicted LC-MS/MSNot Available
LC-MS/MS Spectrum - LC-ESI-qTof , PositiveLC-MS/MSNot Available
LC-MS/MS Spectrum - LC-ESI-QQ , negativeLC-MS/MSsplash10-03di-0090000000-1c4689e9576e27bd1a05
LC-MS/MS Spectrum - LC-ESI-QQ , negativeLC-MS/MSsplash10-03e9-0970000000-546f2f834e7b6b7cfe2b
LC-MS/MS Spectrum - LC-ESI-QQ , negativeLC-MS/MSsplash10-001i-0900000000-56c01857b95c2c352e8f
LC-MS/MS Spectrum - LC-ESI-QQ , negativeLC-MS/MSsplash10-001i-0900000000-5e1208b8b3b63160e22d
LC-MS/MS Spectrum - LC-ESI-QQ , negativeLC-MS/MSsplash10-001i-1900000000-ffbe58f385a5d567f860
LC-MS/MS Spectrum - LC-ESI-QTOF , negativeLC-MS/MSsplash10-03di-0590000000-af07b2b8e7fbdea65fb7
LC-MS/MS Spectrum - LC-ESI-QTOF , negativeLC-MS/MSsplash10-001i-0900000000-198b257593640a2a3d6b
LC-MS/MS Spectrum - LC-ESI-QTOF , negativeLC-MS/MSsplash10-001i-0900000000-e8352f0ffbc6840b9b7d
LC-MS/MS Spectrum - LC-ESI-QTOF , positiveLC-MS/MSsplash10-014i-1090000000-41ad42056b51b72ce86a
LC-MS/MS Spectrum - LC-ESI-QTOF , positiveLC-MS/MSsplash10-001i-9110000000-43394feb6e4bdfeecb4d
LC-MS/MS Spectrum - LC-ESI-QTOF , positiveLC-MS/MSsplash10-001i-9000000000-ae066c9cd1bdc816afb5
LC-MS/MS Spectrum - LC-ESI-QTOF , positiveLC-MS/MSsplash10-0f89-9000000000-4ccae572aad078c08f52
LC-MS/MS Spectrum - LC-ESI-QTOF , positiveLC-MS/MSsplash10-014i-0290000000-b940cd29b82e850fbde2
LC-MS/MS Spectrum - LC-ESI-QTOF , positiveLC-MS/MSsplash10-014j-0950000000-23164321e4dbcf56bfc8
LC-MS/MS Spectrum - LC-ESI-QTOF , positiveLC-MS/MSsplash10-0002-0900000000-3bcaa7373b3d41fc3c53
LC-MS/MS Spectrum - LC-ESI-QQ , positiveLC-MS/MSsplash10-014i-0090000000-39566aaa0d90cfa55b52
LC-MS/MS Spectrum - LC-ESI-QQ , positiveLC-MS/MSsplash10-00lr-9470000000-5aff4f962e7ab520661d
LC-MS/MS Spectrum - LC-ESI-QQ , positiveLC-MS/MSsplash10-001i-9100000000-f788a5e19f6a3220a46e
LC-MS/MS Spectrum - LC-ESI-QQ , positiveLC-MS/MSsplash10-001i-9000000000-7de17409d6536653c15b
LC-MS/MS Spectrum - LC-ESI-QQ , positiveLC-MS/MSsplash10-001i-9000000000-350a42e41eabc5508387
LC-MS/MS Spectrum - LC-ESI-IT , positiveLC-MS/MSsplash10-0002-0900000000-60255f48f53b12ccabdb
LC-MS/MS Spectrum - LC-ESI-ITFT , positiveLC-MS/MSsplash10-000j-1900000000-2da87fbd4f02843b5ef7
LC-MS/MS Spectrum - LC-ESI-ITFT , positiveLC-MS/MSsplash10-000j-1900000000-e44f747bcdfd826b4ad6
LC-MS/MS Spectrum - LC-ESI-ITFT , positiveLC-MS/MSsplash10-000j-0900000000-288da60706864d3f5527
LC-MS/MS Spectrum - LC-ESI-ITFT , positiveLC-MS/MSsplash10-000j-1900000000-d3d107c198b8dab7e49e
LC-MS/MS Spectrum - LC-ESI-QTOF , positiveLC-MS/MSsplash10-014j-0690000000-48e612f30628ddbf2b65
LC-MS/MS Spectrum - LC-ESI-QTOF , positiveLC-MS/MSsplash10-0002-0900000000-7cc826d8b5efe0d89fd8
LC-MS/MS Spectrum - LC-ESI-QTOF , positiveLC-MS/MSsplash10-014i-0900000000-5579cdd6144259196f31
MS/MS Spectrum - , positiveLC-MS/MSsplash10-0002-0900000000-10207f4b099aa327e945

Taxonomy

Description
This compound belongs to the class of organic compounds known as 6-alkylaminopurines. These are compounds that contain an alkylamine group attached at the 6-position of a purine. Purine is a bicyclic aromatic compound made up of a pyrimidine ring fused to an imidazole ring.
Kingdom
Organic compounds
Super Class
Organoheterocyclic compounds
Class
Imidazopyrimidines
Sub Class
Purines and purine derivatives
Direct Parent
6-alkylaminopurines
Alternative Parents
Secondary alkylarylamines / Aminopyrimidines and derivatives / Imidolactams / Imidazoles / Heteroaromatic compounds / Furans / Oxacyclic compounds / Azacyclic compounds / Organopnictogen compounds / Organooxygen compounds
show 1 more
Substituents
6-alkylaminopurine / Aminopyrimidine / Secondary aliphatic/aromatic amine / Pyrimidine / Imidolactam / Azole / Furan / Imidazole / Heteroaromatic compound / Secondary amine
show 10 more
Molecular Framework
Aromatic heteropolycyclic compounds
External Descriptors
furans, 6-aminopurines (CHEBI:27407) / a small molecule (CPD-4609)

Drug created on December 03, 2015 09:52 / Updated on November 02, 2018 07:09