This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Generic Name
- Ascorbyl phosphate
- DrugBank Accession Number
- DB11352
- Background
Ascorbyl phosphate is a synthetic form of Vitamin C and is found in different salt forms such as magnesium ascorbyl phosphate and sodium ascorbyl phosphate. These salts are present in cosmetic products at concentrations ranging from 0.001 % to 3% 1. As vitamin C is susceptible to breakdown of compound and discoloration in cosmetic formulations, ascorbyl phosphate, along with other Vitamin C derivatives, acts as an active and stable precursor of vitamin C that is readily absorbed into the skin with a hydrating effect on the skin 2. While ascorbyl phosphate salts provide a constant delivery of vitamin C into the skin, they also mediate an antioxidant action to act as a free radical scavenger and increases collagen production in vitro 2.
- Type
- Small Molecule
- Groups
- Approved
- Synonyms
- Not Available
Pharmacology
- Indication
Not Available
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Prevent Adverse Drug Events TodayTap into our Clinical API for life-saving information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.Avoid life-threatening adverse drug events with our Clinical API- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Drug Interaction Integrate drug-drug
interactions in your softwareDoxycycline The therapeutic efficacy of Doxycycline can be decreased when used in combination with Ascorbyl phosphate. Erythromycin The therapeutic efficacy of Erythromycin can be decreased when used in combination with Ascorbyl phosphate. Kanamycin The therapeutic efficacy of Kanamycin can be decreased when used in combination with Ascorbyl phosphate. Lincomycin The therapeutic efficacy of Lincomycin can be decreased when used in combination with Ascorbyl phosphate. Streptomycin The therapeutic efficacy of Streptomycin can be decreased when used in combination with Ascorbyl phosphate. - Food Interactions
- No interactions found.
Products
Drug product information from 10+ global regionsOur datasets provide approved product information including:dosage, form, labeller, route of administration, and marketing period.Access drug product information from over 10 global regions.- Product Ingredients
Ingredient UNII CAS InChI Key Magnesium ascorbyl phosphate 0R822556M5 113170-55-1 PBSRSWFGYPZDAU-FFIPNUABSA-H - Active Moieties
Name Kind UNII CAS InChI Key Ascorbic acid unknown PQ6CK8PD0R 50-81-7 CIWBSHSKHKDKBQ-JLAZNSOCSA-N - Over the Counter Products
Name Dosage Strength Route Labeller Marketing Start Marketing End Region Image ELCURE C Serum Liquid 500 mg/50mL Topical Elcure Co., Ltd. 2012-12-31 2017-04-20 US 
ELCURE Vitamin C Serum Liquid 1.5 g/50mL Topical Elcure Co., Ltd. 2011-08-22 2017-04-20 US K Oxiderm OP Post Procedure skin care bruise Cream 0.5 g/100mL Topical Ezekielcosmetic Co., Ltd 2017-08-17 Not applicable US - Mixture Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image Le-Blen Vitamin C Serum Magnesium ascorbyl phosphate (0.57 g/56.7g) + Sodium hyaluronate (2.84 g/56.7g) Lotion Topical LeBlen Beauty Inc 2018-04-24 Not applicable US - Unapproved/Other Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image ELCURE C Serum Magnesium ascorbyl phosphate (500 mg/50mL) Liquid Topical Elcure Co., Ltd. 2012-12-31 2017-04-20 US ELCURE Vitamin C Serum Magnesium ascorbyl phosphate (1.5 g/50mL) Liquid Topical Elcure Co., Ltd. 2011-08-22 2017-04-20 US K Oxiderm OP Post Procedure skin care bruise Magnesium ascorbyl phosphate (0.5 g/100mL) Cream Topical Ezekielcosmetic Co., Ltd 2017-08-17 Not applicable US Le-Blen Vitamin C Serum Magnesium ascorbyl phosphate (0.57 g/56.7g) + Sodium hyaluronate (2.84 g/56.7g) Lotion Topical LeBlen Beauty Inc 2018-04-24 Not applicable US
Categories
- Drug Categories
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- Not Available
- CAS number
- Not Available
- InChI Key
- Not Available
- InChI
- Not Available
- IUPAC Name
- Not Available
- SMILES
- Not Available
References
- General References
- Klock J, Ikeno H, Ohmori K, Nishikawa T, Vollhardt J, Schehlmann V: Sodium ascorbyl phosphate shows in vitro and in vivo efficacy in the prevention and treatment of acne vulgaris. Int J Cosmet Sci. 2005 Jun;27(3):171-6. doi: 10.1111/j.1467-2494.2005.00263.x. [Article]
- Telang PS: Vitamin C in dermatology. Indian Dermatol Online J. 2013 Apr;4(2):143-6. doi: 10.4103/2229-5178.110593. [Article]
- External Links
Clinical Trials
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Liquid Topical 500 mg/50mL Liquid Topical 1.5 g/50mL Cream Topical 0.5 g/100mL Lotion Topical - Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
- Not Available
- Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Not Available
- Chromatographic Properties
Collision Cross Sections (CCS)
Not Available
Drug created at December 03, 2015 16:52 / Updated at June 12, 2020 16:53