Ferric oxide

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

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Name
Ferric oxide
Accession Number
DB11576
Type
Small Molecule
Groups
Experimental
Description

Iron(III) oxide or ferric oxide is the inorganic compound with the formula Fe2O3. It is one of the three main oxides of iron, the other two being iron(II) oxide (FeO) the rarer form, and iron(II,III) oxide (Fe3O4) which naturally as magnetite.

Structure
Thumb
Synonyms
  • Anhydrous Ferric Oxide
  • Anhydrous Iron (III) Oxide
  • Blood stone
  • Eisen(III)-oxid
  • Eisentrioxid
  • Ferric oxide red
  • Hematite
  • Indian red
  • Iron oxide
  • Iron oxide red
  • Iron oxide, red
  • Iron trioxide
  • Iron(III) oxide
External IDs
215-168-2 / E 172 Red
Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing End
Anti Monkey Butt Diaper RashFerric oxide (0.001 g/1g) + Zinc oxide (0.139 g/1g)CreamTopicalDse Healthcare Solutions, Llc.2012-04-18Not applicableUs
Anti Monkey Butt Diaper RashFerric oxide (0.001 g/1g) + Zinc oxide (0.139 g/1g)CreamTopicalDse Healthcare Solutions, Llc.2010-05-012012-04-16Us
Au Kah Chuen FugicalFerric oxide (0.05 g/100g) + Diphenhydramine hydrochloride (2 g/100g) + Zinc oxide (9.95 g/100g)CreamTopicalZhejiang Dingtai Pharmaceutical Co., Ltd2019-06-10Not applicableUs
Aveeno Anti Itch ConcentratedFerric oxide (0.6 mg/1mL) + Pramoxine hydrochloride (10 mg/1mL) + Zinc oxide (29.4 mg/1mL)LotionTopicalJohnson & Johnson Consumer Inc.2012-11-072023-12-01Us
Aveeno Anti-Itch ConcentratedFerric oxide (0.6 mg/1mL) + Pramoxine hydrochloride (10 mg/1mL) + Zinc oxide (29.4 mg/1mL)LotionTopicalJohnson & Johnson Consumer Inc.2019-03-01Not applicableUs
Aveeno Anti-itch LotionFerric oxide (3.0 %) + Pramoxine hydrochloride (1.0 %) + Zinc oxide (3.0 %)LotionTopicalJohnson & Johnson2000-05-01Not applicableCanada
Aveeno Calamine and Pramoxine Hydrochloride Anti ItchFerric oxide (0.6 mg/1g) + Pramoxine hydrochloride (10 mg/1g) + Zinc oxide (29.4 mg/1g)CreamTopicalJohnson & Johnson Consumer Inc.2013-06-202023-12-01Us
Baby Anti Monkey Butt Diaper RashFerric oxide (0.004 g/1g) + Zinc oxide (0.076 g/1g)PowderTopicalClarion Brands, Llc2016-01-01Not applicableUs
Baby Anti Monkey Butt Diaper RashFerric oxide (0.02 g/1g) + Zinc oxide (0.12 g/1g)CreamTopicalClarion Brands, Llc2016-03-01Not applicableUs
Baby Anti Monkey Butt Diaper RashFerric oxide (0.02 g/1g) + Zinc oxide (0.12 g/1g)CreamTopicalDenison Pharmaceuticals, Llc.2017-01-01Not applicableUs
Categories
UNII
1K09F3G675
CAS number
1309-37-1
Weight
Average: 159.687
Monoisotopic: 159.854616
Chemical Formula
Fe2O3
InChI Key
JEIPFZHSYJVQDO-UHFFFAOYSA-N
InChI
InChI=1S/2Fe.3O
IUPAC Name
oxo[(oxoferrio)oxy]iron
SMILES
O=[Fe]O[Fe]=O

Pharmacology

Indication
Not Available
Pharmacodynamics
Not Available
Mechanism of action
Not Available
Additional Data Available
Adverse Effects

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Additional Data Available
Contraindications

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Additional Data Available
Blackbox Warnings

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Absorption
Not Available
Volume of distribution
Not Available
Protein binding
Not Available
Metabolism
Not Available
Route of elimination
Not Available
Half life
Not Available
Clearance
Not Available
Toxicity
Not Available
Affected organisms
Not Available
Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
DrugInteraction
3-Aza-2,3-Dihydrogeranyl DiphosphateFerric oxide can cause a decrease in the absorption of 3-Aza-2,3-Dihydrogeranyl Diphosphate resulting in a reduced serum concentration and potentially a decrease in efficacy.
Alendronic acidFerric oxide can cause a decrease in the absorption of Alendronic acid resulting in a reduced serum concentration and potentially a decrease in efficacy.
AlmasilateAlmasilate can cause a decrease in the absorption of Ferric oxide resulting in a reduced serum concentration and potentially a decrease in efficacy.
AloglutamolAloglutamol can cause a decrease in the absorption of Ferric oxide resulting in a reduced serum concentration and potentially a decrease in efficacy.
AluminiumAluminium can cause a decrease in the absorption of Ferric oxide resulting in a reduced serum concentration and potentially a decrease in efficacy.
Aluminium acetoacetateAluminium acetoacetate can cause a decrease in the absorption of Ferric oxide resulting in a reduced serum concentration and potentially a decrease in efficacy.
Aluminium glycinateAluminium glycinate can cause a decrease in the absorption of Ferric oxide resulting in a reduced serum concentration and potentially a decrease in efficacy.
Aluminium phosphateAluminium phosphate can cause a decrease in the absorption of Ferric oxide resulting in a reduced serum concentration and potentially a decrease in efficacy.
Aluminum hydroxideAluminum hydroxide can cause a decrease in the absorption of Ferric oxide resulting in a reduced serum concentration and potentially a decrease in efficacy.
AsenapineAsenapine can cause a decrease in the absorption of Ferric oxide resulting in a reduced serum concentration and potentially a decrease in efficacy.
Additional Data Available
  • Extended Description
    Extended Description

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  • Severity
    Severity

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    Evidence Level

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  • Action
    Action

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Food Interactions
Not Available

References

General References
Not Available
External Links
KEGG Drug
D04168
KEGG Compound
C19424
ChemSpider
452497
ChEBI
50819
Wikipedia
Iron(III)_oxide
ATC Codes
V08CB03 — Iron oxide, nanoparticles

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
4CompletedTreatmentMelasma1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage forms
FormRouteStrength
CreamTopical
LotionTopical
PowderTopical
SuspensionTopical
Aerosol, sprayTopical
OintmentTopical
LiquidTopical
OintmentRectal; Topical
DressingTopical
PasteTopical
Prices
Not Available
Patents
Not Available

Properties

State
Solid
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
logP0.37ChemAxon
pKa (Strongest Basic)-3ChemAxon
Physiological Charge0ChemAxon
Hydrogen Acceptor Count2ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area43.37 Å2ChemAxon
Rotatable Bond Count2ChemAxon
Refractivity4.24 m3·mol-1ChemAxon
Polarizability7.03 Å3ChemAxon
Number of Rings0ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterNoChemAxon
Veber's RuleNoChemAxon
MDDR-like RuleNoChemAxon
Predicted ADMET features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
SpectrumSpectrum TypeSplash Key
Predicted MS/MS Spectrum - 10V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 20V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 40V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 10V, Negative (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 20V, Negative (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 40V, Negative (Annotated)Predicted LC-MS/MSNot Available

Taxonomy

Description
This compound belongs to the class of inorganic compounds known as transition metal oxides. These are inorganic compounds containing an oxygen atom of an oxidation state of -2, in which the heaviest atom bonded to the oxygen is a transition metal.
Kingdom
Inorganic compounds
Super Class
Mixed metal/non-metal compounds
Class
Transition metal organides
Sub Class
Transition metal oxides
Direct Parent
Transition metal oxides
Alternative Parents
Inorganic salts / Inorganic oxides
Substituents
Transition metal oxide / Inorganic oxide / Inorganic salt
Molecular Framework
Not Available
External Descriptors
iron oxide (CHEBI:50819)

Drug created on April 11, 2016 21:00 / Updated on July 13, 2019 00:57