Carbon monoxide

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Name
Carbon monoxide
Accession Number
DB11588
Type
Small Molecule
Groups
Approved, Investigational
Description

Carbon monoxide (CO) is a colorless, odorless, and tasteless gas that is slightly less dense than air. It is toxic to hemoglobic animals (including humans) when encountered in concentrations above about 35 ppm, although it is also produced in normal animal metabolism in low quantities, and is thought to have some normal biological functions.

Structure
Thumb
Synonyms
  • carbon(II) oxide
  • Carboneum oxygenisatum
  • CO
Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing End
Carbon Monox, Helium, Oxygen, Nitrogen L.D.M.Carbon monoxide (0.3 %) + Helium (10.5 %) + Nitrogen (67.7 %) + Oxygen (21.5 %)GasRespiratory (inhalation)Praxair, Inc.1993-12-31Not applicableCanada
Carbon Monoxide, Compressed Air Medical G.M.Carbon monoxide (0.3 %) + Medical air (99.7 %)GasRespiratory (inhalation)Praxair, Inc.1993-12-31Not applicableCanada
Co-HE-O2-N2 MixtureCarbon monoxide (0.3 %) + Helium (10.0 %) + Nitrogen (68.7 %) + Oxygen (21.0 %)GasRespiratory (inhalation)Linde Llc1995-12-31Not applicableCanada
Co-NE-O2-N2 MixtureCarbon monoxide (0.3 %) + Neon (0.5 %) + Nitrogen (78.2 %) + Oxygen (21.0 %)GasRespiratory (inhalation)Linde Llc1995-12-31Not applicableCanada
Lung Diffusion Test Mix No Ne CoCarbon monoxide (0.3 %) + Neon (0.5 %) + Nitrogen (78.2 %) + Oxygen (21 %)GasRespiratory (inhalation)Praxair, Inc.1968-12-31Not applicableCanada
Lung Diffusion Test Mix NohcoCarbon monoxide (.3 %) + Helium (10 %) + Nitrogen (68.7 %) + Oxygen (21 %)GasRespiratory (inhalation)Liquid Carbonic Inc.1968-12-311998-06-09Canada
Lung Diffusion Test MixtureCarbon monoxide (.5 %) + Helium (15 %) + Nitrogen (74 %) + Oxygen (23 %)GasRespiratory (inhalation)Matheson Gas Products Canada Inc.1982-12-311997-12-24Canada
Lung Diffusion Test MixtureCarbon monoxide (.4 %) + Medical air (99.99 %)GasRespiratory (inhalation)Matheson Gas Products Canada Inc.1982-12-311997-12-24Canada
Lung Diffusion Test Mixture GasCarbon monoxide (0.1 %) + Helium (10 %) + Nitrogen (68.9 %) + Oxygen (21 %)GasRespiratory (inhalation)Praxair, Inc.1997-05-02Not applicableCanada
Categories
UNII
7U1EE4V452
CAS number
630-08-0
Weight
Average: 28.01
Monoisotopic: 27.99491462
Chemical Formula
CO
InChI Key
UGFAIRIUMAVXCW-UHFFFAOYSA-N
InChI
InChI=1S/CO/c1-2
IUPAC Name
SMILES

Pharmacology

Indication
Not Available
Structured Indications
Not Available
Pharmacodynamics
Not Available
Mechanism of action
Not Available
Absorption
Not Available
Volume of distribution
Not Available
Protein binding
Not Available
Metabolism
Not Available
Route of elimination
Not Available
Half life
Not Available
Clearance
Not Available
Toxicity
Not Available
Affected organisms
Not Available
Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
Not Available
Food Interactions
Not Available

References

General References
Not Available
External Links
Human Metabolome Database
HMDB0001361
KEGG Drug
D09706
KEGG Compound
C00237
PubChem Compound
281
PubChem Substance
347827995
ChemSpider
275
ChEBI
17245
ChEMBL
CHEMBL1231840
HET
CMO
Wikipedia
Carbon_monoxide
PDB Entries
1a6g / 1a9w / 1abs / 1aj9 / 1ajg / 1ajh / 1bbb / 1bzr / 1cbm / 1cg8
show 331 more

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
1CompletedTreatmentRespiratory Distress Syndrome, Adult1
1RecruitingOtherEndothelial Dysfunction1
1TerminatedTreatmentHealthy Volunteers1
1, 2WithdrawnTreatmentPulmonary Hypertension (PH)1
2Active Not RecruitingTreatmentIdiopathic Pulmonary Fibrosis (IPF)1
2CompletedTreatmentPulmonary Disease, Chronic Obstructive1
2TerminatedTreatmentIleus1
3Active Not RecruitingTreatmentInfection, Human Immunodeficiency Virus I1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage forms
FormRouteStrength
GasRespiratory (inhalation)
Prices
Not Available
Patents
Not Available

Properties

State
Solid
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility6.37 mg/mLALOGPS
logP-0.06ALOGPS
logS-1.1ALOGPS
Physiological Charge0ChemAxon
Hydrogen Acceptor Count0ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area0 Å2ChemAxon
Rotatable Bond Count0ChemAxon
Refractivity26.23 m3·mol-1ChemAxon
Polarizability1.94 Å3ChemAxon
Number of Rings0ChemAxon
Bioavailability1ChemAxon
Rule of FiveNoChemAxon
Ghose FilterNoChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleNoChemAxon
Predicted ADMET features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
SpectrumSpectrum TypeSplash Key
Mass Spectrum (Electron Ionization)MSsplash10-004i-9000000000-dfbb2bd73fc3d527a340
Predicted MS/MS Spectrum - 10V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 20V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 40V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 10V, Negative (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 20V, Negative (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 40V, Negative (Annotated)Predicted LC-MS/MSNot Available

Taxonomy

Description
This compound belongs to the class of inorganic compounds known as homogeneous other non-metal compounds. These are inorganic non-metallic compounds in which the largest atom belongs to the class of 'other non-metals'.
Kingdom
Inorganic compounds
Super Class
Homogeneous non-metal compounds
Class
Homogeneous other non-metal compounds
Sub Class
Not Available
Direct Parent
Homogeneous other non-metal compounds
Alternative Parents
Not Available
Substituents
Homogeneous other non metal
Molecular Framework
Not Available
External Descriptors
one-carbon compound, carbon oxide (CHEBI:17245) / a small molecule (CARBON-MONOXIDE)

Drug created on April 28, 2016 12:59 / Updated on February 08, 2018 18:16