Seribantumab

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

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Name
Seribantumab
Accession Number
DB11857
Type
Biotech
Groups
Investigational
Biologic Classification
Protein Based Therapies
Monoclonal antibody (mAb)
Description

Seribantumab has been used in trials studying the treatment of NSCLC, Heregulin, Adenocarcinoma, Colorectal Cancer, and Solid Tumor Cancers, among others.

Protein chemical formula
Not Available
Protein average weight
Not Available
Sequences
Not Available
Synonyms
Not Available
External IDs
MM-121
Categories
UNII
1N3L70MDFX
CAS number
1334296-12-6

Pharmacology

Indication
Not Available
Pharmacodynamics
Not Available
Mechanism of action
Not Available
Absorption
Not Available
Volume of distribution
Not Available
Protein binding
Not Available
Metabolism
Not Available
Route of elimination
Not Available
Half life
Not Available
Clearance
Not Available
Toxicity
Not Available
Affected organisms
Not Available
Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
DrugInteraction
AbciximabThe risk or severity of adverse effects can be increased when Abciximab is combined with Seribantumab.
AbituzumabThe risk or severity of adverse effects can be increased when Seribantumab is combined with Abituzumab.
AbrilumabThe risk or severity of adverse effects can be increased when Seribantumab is combined with Abrilumab.
AdalimumabThe risk or severity of adverse effects can be increased when Adalimumab is combined with Seribantumab.
AdecatumumabThe risk or severity of adverse effects can be increased when Adecatumumab is combined with Seribantumab.
AducanumabThe risk or severity of adverse effects can be increased when Seribantumab is combined with Aducanumab.
AfelimomabThe risk or severity of adverse effects can be increased when Afelimomab is combined with Seribantumab.
AlemtuzumabThe risk or severity of adverse effects can be increased when Alemtuzumab is combined with Seribantumab.
AlirocumabThe risk or severity of adverse effects can be increased when Alirocumab is combined with Seribantumab.
AmatuximabThe risk or severity of adverse effects can be increased when Seribantumab is combined with Amatuximab.
Additional Data Available
  • Extended Description
    Extended Description

    Extended description of the mechanism of action and particular properties of each drug interaction.

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  • Severity
    Severity

    A severity rating for each drug interaction, from minor to major.

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  • Evidence Level
    Evidence Level

    A rating for the strength of the evidence supporting each drug interaction.

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  • Action
    Action

    An effect category for each drug interaction. Know how this interaction affects the subject drug.

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Food Interactions
Not Available

References

General References
Not Available
External Links
PubChem Substance
347911251
Wikipedia
Seribantumab

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
1CompletedTreatmentAdvanced Solid Tumors1
1CompletedTreatmentColorectal Cancers / Lung Cancer Non-Small Cell Cancer (NSCLC) / Other Tumors With EGFR Dependence / Squamous Cell Head and Neck Cancer / Triple Negative Breast Cancer (TNBC)1
1CompletedTreatmentLocally Advanced/Metastatic Her2 Non Overexpressing Breast Cancer / Locally Advanced/Metastatic or Recurrent Ovarian Cancer, Fallopian Tube Cancer / Primary Peritoneal Cancer or Endometrial Cancer1
1CompletedTreatmentSolid Tumor Cancers1
1CompletedTreatmentTumors, Solid1
1RecruitingTreatmentColorectal Cancers / Lung Cancer Non-Small Cell Cancer (NSCLC) / Squamous Cell Carcinoma of the Head and Neck (SCCHN)1
1, 2CompletedTreatmentLung Cancer Non-Small Cell Cancer (NSCLC)1
2CompletedTreatmentER Positive, Her2 Negative Breast Cancer Patients / Triple Negative Breast Cancer Patients1
2CompletedTreatmentFallopian Tube Cancer / Malignant Peritoneal Neoplasm / Ovarian Epithelial Cancer1
2CompletedTreatmentHer2 Negative Breast Cancer Patients1
2RecruitingTreatmentAdenocarcinomas / Carcinoma, Large Cell / Heregulin / Lung Cancer Non-Small Cell Cancer (NSCLC) / Squamous Cell Carcinoma (SCC)1
2RecruitingTreatmentMetastatic Breast Cancer (MBC)1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available

Taxonomy

Description
Not Available
Kingdom
Organic Compounds
Super Class
Organic Acids
Class
Carboxylic Acids and Derivatives
Sub Class
Amino Acids, Peptides, and Analogues
Direct Parent
Peptides
Alternative Parents
Not Available
Substituents
Not Available
Molecular Framework
Not Available
External Descriptors
Not Available

Drug created on October 20, 2016 14:54 / Updated on June 04, 2019 07:28