Showing BioInteractions for Nafamostat (DB12598)
BioInteractor utilizes data on drug-target, -enzyme and -transporter associations to provide insight on drug-drug interactions. It allows you to identify, for instance, which drugs act similarly on the same target. Such drugs may have additive pharmacodynamic effects if given concomitantly. Conversely, two drugs may antagonize the beneficial effects of each other by having opposite actions on a specific drug target. BioInteractor uses ranked drug-enzyme association information to predict enzyme-mediated drug interactions that may be clinically relevant.
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Nafamostat is a Intercellular adhesion molecule 1 inhibitor | ||
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Nafamostat is a Trypsin-1 inhibitor | ||
| 1 | Trypsin-1 inhibitors | Camostat, Gabexate, RWJ-56423 |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Nafamostat is a Kallikrein-1 inhibitor | ||
| 1 | Kallikrein-1 inhibitors | Aluminium |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Nafamostat is a Prothrombin inhibitor | ||
| 1 | Prothrombin inhibitors | Antithrombin Alfa, Argatroban, Betrixaban, Bivalirudin, Conestat alfa, Dabigatran etexilate, Gabexate, Human C1-esterase inhibitor, Lepirudin, Suramin, Thrombomodulin Alfa, Ximelagatran |
| 2 | Prothrombin activators | Antihemophilic factor, human recombinant, Lonoctocog alfa, Menadione, Moroctocog alfa |
| 3 | Prothrombin agonists | Anti-inhibitor coagulant complex, Kappadione |
| 4 | Prothrombin substrates | Anti-inhibitor coagulant complex |
| 5 | Prothrombin binders | Turoctocog alfa, Turoctocog alfa pegol |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Nafamostat is a Coagulation factor X inhibitor | ||
| 1 | Coagulation factor X activators | Albutrepenonacog alfa, Antihemophilic factor human, Antihemophilic factor, human recombinant, Coagulation Factor IX (Recombinant), Coagulation Factor IX Human, Coagulation factor VII human, Emicizumab, Lonoctocog alfa, Moroctocog alfa, Turoctocog alfa, Turoctocog alfa pegol |
| 2 | Coagulation factor X inhibitors | Antithrombin Alfa, Apixaban, Betrixaban, Edoxaban, Enoxaparin, Fondaparinux, Heparin |
| 3 | Coagulation factor X antagonists | Bemiparin, Protein S human, Rivaroxaban |
| 4 | Coagulation factor X substrates | Prothrombin, Turoctocog alfa pegol |
| 5 | Coagulation factor X agonists | Anti-inhibitor coagulant complex, Kappadione, Nonacog beta pegol |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Nafamostat is a Coagulation factor XII inhibitor | ||
| 1 | Coagulation factor XII activators | Ethanolamine oleate |
| 2 | Coagulation factor XII inhibitors | Conestat alfa, Human C1-esterase inhibitor |