Radium Ra-223

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

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Name
Radium Ra-223
Accession Number
DB12813
Type
Small Molecule
Groups
Investigational
Description

Radium 223 is under investigation in clinical trial NCT02463799 (Ph 2 Study of Sipuleucel-T W/ or W/O Radium-223 in Men With Asymptomatic or Minimally Symptomatic Bone-MCRPC).

Structure
Thumb
Synonyms
  • Radium-223
Categories
Not Available
UNII
8BR2SOL3L1
CAS number
15623-45-7
Weight
Average: 223.0185
Monoisotopic: 223.01849714
Chemical Formula
Ra
InChI Key
HCWPIIXVSYCSAN-OIOBTWANSA-N
InChI
InChI=1S/Ra/i1-3
IUPAC Name
(223Ra)radium
SMILES
[223Ra]

Pharmacology

Indication
Not Available
Pharmacodynamics
Not Available
Mechanism of action
Not Available
Absorption
Not Available
Volume of distribution
Not Available
Protein binding
Not Available
Metabolism
Not Available
Route of elimination
Not Available
Half life
Not Available
Clearance
Not Available
Toxicity
Not Available
Affected organisms
Not Available
Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
Not Available
Food Interactions
Not Available

References

General References
Not Available
External Links
PubChem Compound
6335825
PubChem Substance
347828986
ChemSpider
4891413

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
0TerminatedTreatmentTransitional Cell Carcinoma1
2Active Not RecruitingSupportive CareMetastatic Hormone Refractory Prostate Cancer / Pain NOS1
2RecruitingTreatmentMetastatic Castration Resistant Prostate Cancer1
3RecruitingTreatmentProstate Cancer1
Not AvailableActive Not RecruitingNot AvailableAdvanced Prostate Cancer / Castration resistant / Prostate Cancer / Radium 2231
Not AvailableActive Not RecruitingNot AvailableMetastatic Castration-Resistant Prostate Cancer (mCRPC)1
Not AvailableCompletedNot AvailableProstatic Neoplasms, Castration-Resistant1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
logP0ChemAxon
Physiological Charge0ChemAxon
Hydrogen Acceptor Count0ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area0 Å2ChemAxon
Rotatable Bond Count0ChemAxon
Refractivity0 m3·mol-1ChemAxon
Polarizability1.78 Å3ChemAxon
Number of Rings0ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterNoChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleNoChemAxon
Predicted ADMET features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
SpectrumSpectrum TypeSplash Key
Predicted MS/MS Spectrum - 10V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 20V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 40V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 10V, Negative (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 20V, Negative (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 40V, Negative (Annotated)Predicted LC-MS/MSNot Available

Taxonomy

Description
This compound belongs to the class of inorganic compounds known as homogeneous alkaline earth metal compounds. These are inorganic compounds containing only metal atoms,with the largest atom being a alkaline earth metal atom.
Kingdom
Inorganic compounds
Super Class
Homogeneous metal compounds
Class
Homogeneous alkaline earth metal compounds
Sub Class
Not Available
Direct Parent
Homogeneous alkaline earth metal compounds
Alternative Parents
Not Available
Substituents
Homogeneous alkaline earth metal
Molecular Framework
Not Available
External Descriptors
Not Available

Drug created on October 20, 2016 18:26 / Updated on June 04, 2019 07:43