Showing BioInteractions for Protein S human (DB13149)
BioInteractor utilizes data on drug-target, -enzyme and -transporter associations to provide insight on drug-drug interactions. It allows you to identify, for instance, which drugs act similarly on the same target. Such drugs may have additive pharmacodynamic effects if given concomitantly. Conversely, two drugs may antagonize the beneficial effects of each other by having opposite actions on a specific drug target. BioInteractor uses ranked drug-enzyme association information to predict enzyme-mediated drug interactions that may be clinically relevant.
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Protein S human is a Coagulation factor V antagonist | ||
| 1 | Coagulation factor V binders | Copper |
| 2 | Coagulation factor V agonists | Anti-inhibitor coagulant complex |
| 3 | Coagulation factor V substrates | Anti-inhibitor coagulant complex |
| 4 | Coagulation factor V activators | Human thrombin, Thrombin, Thrombin alfa |
| 5 | Coagulation factor V inactivators | Protein C |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Protein S human is a Coagulation factor X antagonist | ||
| 1 | Coagulation factor X activators | Albutrepenonacog alfa, Antihemophilic factor human, Antihemophilic factor, human recombinant, Coagulation Factor IX (Recombinant), Coagulation Factor IX Human, Coagulation factor VII human, Emicizumab, Lonoctocog alfa, Moroctocog alfa, Turoctocog alfa, Turoctocog alfa pegol |
| 2 | Coagulation factor X inhibitors | Antithrombin Alfa, Apixaban, Betrixaban, Edoxaban, Enoxaparin, Fondaparinux, Heparin, Nafamostat |
| 3 | Coagulation factor X antagonists | Bemiparin, Rivaroxaban |
| 4 | Coagulation factor X substrates | Prothrombin, Turoctocog alfa pegol |
| 5 | Coagulation factor X agonists | Anti-inhibitor coagulant complex, Kappadione, Nonacog beta pegol |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Protein S human is a Vitamin K-dependent protein C cofactor | ||
| 1 | Vitamin K-dependent protein C inhibitors | Sodium tetradecyl sulfate |
| 2 | Vitamin K-dependent protein C activators | Menadione |
| 3 | Vitamin K-dependent protein C inactivators | Antihemophilic factor, human recombinant, Lonoctocog alfa, Moroctocog alfa |
| 4 | Vitamin K-dependent protein C substrates | Antihemophilic factor human, Turoctocog alfa pegol |
| 5 | Vitamin K-dependent protein C agonists | Kappadione |