NAV

Stibophen

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name
Stibophen
DrugBank Accession Number
DB13236
Background

Stibophen is used in the treatment of schistosomiasis, a disease of parasitic flatworms.

Type
Small Molecule
Groups
Experimental
Structure
Similar Structures
Weight
Average: 895.2
Monoisotopic: 893.76483
Chemical Formula
C12H18Na5O23S4Sb
Synonyms
Not Available
External IDs
  • SDT-91
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Pharmacology

Indication

Not Available

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Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Categories

ATC Codes
P02BX03 — Stibophen
Drug Categories
Chemical TaxonomyProvided by Classyfire
Description
This compound belongs to the class of organic compounds known as benzenesulfonic acids and derivatives. These are organic compounds containing a sulfonic acid or a derivative thereof that is linked to a benzene ring.
Kingdom
Organic compounds
Super Class
Benzenoids
Class
Benzene and substituted derivatives
Sub Class
Benzenesulfonic acids and derivatives
Direct Parent
Benzenesulfonic acids and derivatives
Alternative Parents
Benzenesulfonyl compounds / 1-sulfo,2-unsubstituted aromatic compounds / Phenoxides / Sulfonyls / Organosulfonic acids / Organic antimony salts / Organooxygen compounds / Organic sodium salts / Organic oxides / Hydrocarbon derivatives
show 1 more
Substituents
1-sulfo,2-unsubstituted aromatic compound / Aromatic homomonocyclic compound / Arylsulfonic acid or derivatives / Benzenesulfonate / Benzenesulfonyl group / Hydrocarbon derivative / Organic alkali metal salt / Organic antimony salt / Organic cation / Organic metalloid salt
show 11 more
Molecular Framework
Not Available
External Descriptors
Not Available
Affected organisms
Not Available

Chemical Identifiers

UNII
6CM08O30EH
CAS number
15489-16-4
InChI Key
ZDDUXABBRATYFS-UHFFFAOYSA-F
InChI
InChI=1S/2C6H6O8S2.5Na.7H2O.Sb/c2*7-4-1-3(15(9,10)11)2-5(6(4)8)16(12,13)14;;;;;;;;;;;;;/h2*1-2,7-8H,(H,9,10,11)(H,12,13,14);;;;;;7*1H2;/q;;5*+1;;;;;;;;+3/p-8
IUPAC Name
antimony(3+) ion pentasodium bis(3,5-disulfobenzene-1,2-bis(olate)) heptahydrate
SMILES
O.O.O.O.O.O.O.[Na+].[Na+].[Na+].[Na+].[Na+].[Sb+3].[O-]C1=C([O-])C(=CC(=C1)S([O-])(=O)=O)S([O-])(=O)=O.[O-]C1=C([O-])C(=CC(=C1)S([O-])(=O)=O)S([O-])(=O)=O

References

General References
Not Available
ChemSpider
17615576
Wikipedia
Stibophen

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility0.919 mg/mLALOGPS
logP1.04ALOGPS
logP0.38Chemaxon
logS-2.8ALOGPS
pKa (Strongest Acidic)-3.5Chemaxon
pKa (Strongest Basic)-6.5Chemaxon
Physiological Charge-2Chemaxon
Hydrogen Acceptor Count8Chemaxon
Hydrogen Donor Count0Chemaxon
Polar Surface Area160.52 Å2Chemaxon
Rotatable Bond Count4Chemaxon
Refractivity70.12 m3·mol-1Chemaxon
Polarizability20.05 Å3Chemaxon
Number of Rings2Chemaxon
Bioavailability1Chemaxon
Rule of FiveNoChemaxon
Ghose FilterNoChemaxon
Veber's RuleNoChemaxon
MDDR-like RuleNoChemaxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Not Available
Chromatographic Properties
Collision Cross Sections (CCS)
AdductCCS Value (Å2)Source typeSource
[M-H]-160.9556464
predicted
DarkChem Lite v0.1.0
[M+H]+162.1310464
predicted
DarkChem Lite v0.1.0
[M+Na]+160.9989464
predicted
DarkChem Lite v0.1.0

Drug created at June 23, 2017 20:38 / Updated at June 12, 2020 16:53