Ethenzamide

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Name
Ethenzamide
Accession Number
DB13544
Type
Small Molecule
Groups
Experimental
Description
Not Available
Structure
Thumb
Synonyms
  • Etenzamida
  • Etenzamide
  • Ethbenzamide
  • éthenzamide
  • Ethenzamide
  • Ethenzamidum
  • o-Ethoxybenzamide
External IDs
J3.352I / NSC-28787
Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing End
Penzal QEthenzamide (200 mg/1) + Acetaminophen (300 mg/1) + Caffeine (50 mg/1)TabletOralOASIS TRADING2018-11-20Not applicableUs
Categories
UNII
L929ZCK4BF
CAS number
938-73-8
Weight
Average: 165.192
Monoisotopic: 165.078978598
Chemical Formula
C9H11NO2
InChI Key
SBNKFTQSBPKMBZ-UHFFFAOYSA-N
InChI
InChI=1S/C9H11NO2/c1-2-12-8-6-4-3-5-7(8)9(10)11/h3-6H,2H2,1H3,(H2,10,11)
IUPAC Name
2-ethoxybenzene-1-carboximidic acid
SMILES
CCOC1=C(C=CC=C1)C(N)=O

Pharmacology

Indication
Not Available
Pharmacodynamics
Not Available
Mechanism of action
Not Available
Additional Data Available
Adverse Effects

Comprehensive structured data on known drug adverse effects with statistical prevalence. MedDRA and ICD10 ids are provided for adverse effect conditions and symptoms.

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Additional Data Available
Contraindications

Structured data covering drug contraindications. Each contraindication describes a scenario in which the drug is not to be used. Includes restrictions on co-administration, contraindicated populations, and more.

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Additional Data Available
Blackbox Warnings

Structured data representing warnings from the black box section of drug labels. These warnings cover important and dangerous risks, contraindications, or adverse effects.

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Absorption
Not Available
Volume of distribution
Not Available
Protein binding
Not Available
Metabolism
Not Available
Route of elimination
Not Available
Half life
Not Available
Clearance
Not Available
Toxicity
Not Available
Affected organisms
Not Available
Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
DrugInteraction
(R)-warfarinThe risk or severity of bleeding and hemorrhage can be increased when Ethenzamide is combined with (R)-warfarin.
(S)-WarfarinThe risk or severity of bleeding and hemorrhage can be increased when Ethenzamide is combined with (S)-Warfarin.
1-benzylimidazoleThe risk or severity of hypertension can be increased when 1-benzylimidazole is combined with Ethenzamide.
2,5-Dimethoxy-4-ethylamphetamineThe risk or severity of hypertension can be increased when 2,5-Dimethoxy-4-ethylamphetamine is combined with Ethenzamide.
2,5-Dimethoxy-4-ethylthioamphetamineThe risk or severity of hypertension can be increased when Ethenzamide is combined with 2,5-Dimethoxy-4-ethylthioamphetamine.
4-Bromo-2,5-dimethoxyamphetamineThe risk or severity of hypertension can be increased when 4-Bromo-2,5-dimethoxyamphetamine is combined with Ethenzamide.
4-hydroxycoumarinThe risk or severity of bleeding and hemorrhage can be increased when Ethenzamide is combined with 4-hydroxycoumarin.
4-MethoxyamphetamineThe risk or severity of hypertension can be increased when 4-Methoxyamphetamine is combined with Ethenzamide.
5-methoxy-N,N-dimethyltryptamineThe risk or severity of hypertension can be increased when Ethenzamide is combined with 5-methoxy-N,N-dimethyltryptamine.
AbacavirEthenzamide may decrease the excretion rate of Abacavir which could result in a higher serum level.
Additional Data Available
  • Extended Description
    Extended Description

    Extended description of the mechanism of action and particular properties of each drug interaction.

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  • Severity
    Severity

    A severity rating for each drug interaction, from minor to major.

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  • Evidence Level
    Evidence Level

    A rating for the strength of the evidence supporting each drug interaction.

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  • Action
    Action

    An effect category for each drug interaction. Know how this interaction affects the subject drug.

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Food Interactions
Not Available

References

General References
Not Available
External Links
KEGG Drug
D01466
ChemSpider
3167
RxNav
24468
ChEBI
31564
ChEMBL
CHEMBL1483877
ZINC
ZINC000000001384
Wikipedia
Ethenzamide
ATC Codes
N02BA07 — EthenzamideN02BA77 — Ethenzamide, combinations with psycholepticsN02BA57 — Ethenzamide, combinations excl. psycholeptics

Clinical Trials

Clinical Trials
Not Available

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage forms
FormRouteStrength
TabletOral
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility0.841 mg/mLALOGPS
logP1.06ALOGPS
logP1.61ChemAxon
logS-2.3ALOGPS
pKa (Strongest Acidic)7.9ChemAxon
pKa (Strongest Basic)6.2ChemAxon
Physiological Charge1ChemAxon
Hydrogen Acceptor Count3ChemAxon
Hydrogen Donor Count2ChemAxon
Polar Surface Area53.31 Å2ChemAxon
Rotatable Bond Count3ChemAxon
Refractivity57.28 m3·mol-1ChemAxon
Polarizability17.39 Å3ChemAxon
Number of Rings1ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleNoChemAxon
MDDR-like RuleNoChemAxon
Predicted ADMET features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
SpectrumSpectrum TypeSplash Key
GC-MS Spectrum - EI-BGC-MSsplash10-00di-1900000000-bcc16f34f2d38dc44482
GC-MS Spectrum - EI-BGC-MSsplash10-00dl-6900000000-8e77edbc0a9e88098d92
Predicted MS/MS Spectrum - 10V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 20V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 40V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 10V, Negative (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 20V, Negative (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 40V, Negative (Annotated)Predicted LC-MS/MSNot Available

Taxonomy

Description
This compound belongs to the class of organic compounds known as benzamides. These are organic compounds containing a carboxamido substituent attached to a benzene ring.
Kingdom
Organic compounds
Super Class
Benzenoids
Class
Benzene and substituted derivatives
Sub Class
Benzoic acids and derivatives
Direct Parent
Benzamides
Alternative Parents
Phenoxy compounds / Phenol ethers / Benzoyl derivatives / Alkyl aryl ethers / Primary carboxylic acid amides / Organopnictogen compounds / Organonitrogen compounds / Organic oxides / Hydrocarbon derivatives
Substituents
Benzamide / Phenoxy compound / Benzoyl / Phenol ether / Alkyl aryl ether / Carboxamide group / Primary carboxylic acid amide / Carboxylic acid derivative / Ether / Organic nitrogen compound
Molecular Framework
Aromatic homomonocyclic compounds
External Descriptors
Not Available

Drug created on June 23, 2017 14:44 / Updated on March 01, 2020 21:34

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