NAV

Succinylsulfathiazole

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name
Succinylsulfathiazole
DrugBank Accession Number
DB13580
Background

Not Available

Type
Small Molecule
Groups
Experimental
Structure
3D
Similar Structures
Weight
Average: 355.38
Monoisotopic: 355.029662879
Chemical Formula
C13H13N3O5S2
Synonyms
  • Succinylsulfathiazole
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Pharmacology

Indication

Not Available

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Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
DrugInteraction
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interactions in your software
AcarboseThe therapeutic efficacy of Acarbose can be increased when used in combination with Succinylsulfathiazole.
AcetohexamideThe therapeutic efficacy of Acetohexamide can be increased when used in combination with Succinylsulfathiazole.
AlbiglutideThe therapeutic efficacy of Albiglutide can be increased when used in combination with Succinylsulfathiazole.
AlogliptinThe therapeutic efficacy of Alogliptin can be increased when used in combination with Succinylsulfathiazole.
BenzylpenicillinSuccinylsulfathiazole may decrease the excretion rate of Benzylpenicillin which could result in a higher serum level.
Food Interactions
Not Available

Products

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Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
แบคซีลา เม็ดSuccinylsulfathiazole (250 mg) + Diiodohydroxyquinoline (250 mg) + Furazolidone (50 mg) + Neomycin sulfate (50 mg)Tabletบริษัท ไบร์วู๊ดฟาร์มาซูติคอล จำกัด1986-03-072020-07-19Thailand flag

Categories

ATC Codes
A07AB04 — Succinylsulfathiazole
Drug Categories
Chemical TaxonomyProvided by Classyfire
Description
This compound belongs to the class of organic compounds known as benzenesulfonamides. These are organic compounds containing a sulfonamide group that is S-linked to a benzene ring.
Kingdom
Organic compounds
Super Class
Benzenoids
Class
Benzene and substituted derivatives
Sub Class
Benzenesulfonamides
Direct Parent
Benzenesulfonamides
Alternative Parents
Anilides / Benzenesulfonyl compounds / N-arylamides / Organosulfonamides / Fatty amides / Thiazoles / Aminosulfonyl compounds / Heteroaromatic compounds / Secondary carboxylic acid amides / Monocarboxylic acids and derivatives
show 6 more
Substituents
Aminosulfonyl compound / Anilide / Aromatic heteromonocyclic compound / Azacycle / Azole / Benzenesulfonamide / Benzenesulfonyl group / Carbonyl group / Carboxamide group / Carboxylic acid
show 21 more
Molecular Framework
Aromatic heteromonocyclic compounds
External Descriptors
1,3-thiazole (CHEBI:9309)
Affected organisms
Not Available

Chemical Identifiers

UNII
RSS8647O4S
CAS number
116-43-8
InChI Key
SKVLYVHULOWXTD-UHFFFAOYSA-N
InChI
InChI=1S/C13H13N3O5S2/c17-11(5-6-12(18)19)15-9-1-3-10(4-2-9)23(20,21)16-13-14-7-8-22-13/h1-4,7-8H,5-6H2,(H,14,16)(H,15,17)(H,18,19)
IUPAC Name
3-({4-[(1,3-thiazol-2-yl)sulfamoyl]phenyl}carbamoyl)propanoic acid
SMILES
OC(=O)CCC(=O)NC1=CC=C(C=C1)S(=O)(=O)NC1=NC=CS1

References

General References
Not Available
KEGG Compound
C11745
ChemSpider
5124
BindingDB
50238667
RxNav
37289
ChEBI
9309
ChEMBL
CHEMBL1484857
ZINC
ZINC000001532343
Wikipedia
Succinylsulfathiazole

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
Tablet
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility0.185 mg/mLALOGPS
logP0.99ALOGPS
logP0.87Chemaxon
logS-3.3ALOGPS
pKa (Strongest Acidic)3.36Chemaxon
pKa (Strongest Basic)0.59Chemaxon
Physiological Charge-2Chemaxon
Hydrogen Acceptor Count6Chemaxon
Hydrogen Donor Count3Chemaxon
Polar Surface Area125.46 Å2Chemaxon
Rotatable Bond Count6Chemaxon
Refractivity83.33 m3·mol-1Chemaxon
Polarizability33.41 Å3Chemaxon
Number of Rings2Chemaxon
Bioavailability1Chemaxon
Rule of FiveYesChemaxon
Ghose FilterYesChemaxon
Veber's RuleNoChemaxon
MDDR-like RuleNoChemaxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
SpectrumSpectrum TypeSplash Key
LC-MS/MS Spectrum - LC-ESI-qTof , PositiveLC-MS/MSsplash10-052g-2920000000-0aaf9a7c8753d2886e99
MS/MS Spectrum - , positiveLC-MS/MSsplash10-052g-2920000000-0aaf9a7c8753d2886e99
Predicted MS/MS Spectrum - 10V, Positive (Annotated)Predicted LC-MS/MSsplash10-000i-0219000000-c99015c072d24df8e894
Predicted MS/MS Spectrum - 10V, Negative (Annotated)Predicted LC-MS/MSsplash10-0udi-0059000000-cbb2deb424aeaf73f332
Predicted MS/MS Spectrum - 20V, Positive (Annotated)Predicted LC-MS/MSsplash10-052r-2396000000-5d196cb7d5c67441b399
Predicted MS/MS Spectrum - 20V, Negative (Annotated)Predicted LC-MS/MSsplash10-0udi-1392000000-f936ba504a39df7fc1d2
Predicted MS/MS Spectrum - 40V, Positive (Annotated)Predicted LC-MS/MSsplash10-006y-6911000000-ea9ffffa24fa4042001b
Predicted MS/MS Spectrum - 40V, Negative (Annotated)Predicted LC-MS/MSsplash10-00kf-9413000000-8f3e238d61e5f8f03bdb
Predicted 1H NMR Spectrum1D NMRNot Applicable
Predicted 13C NMR Spectrum1D NMRNot Applicable
Chromatographic Properties
Collision Cross Sections (CCS)
AdductCCS Value (Å2)Source typeSource
[M-H]-196.0078336
predicted
DarkChem Lite v0.1.0
[M-H]-169.21407
predicted
DeepCCS 1.0 (2019)
[M+H]+195.7988336
predicted
DarkChem Lite v0.1.0
[M+H]+171.57204
predicted
DeepCCS 1.0 (2019)
[M+Na]+178.28322
predicted
DeepCCS 1.0 (2019)

Drug created at June 23, 2017 20:44 / Updated at February 21, 2021 18:54