Meglumine antimoniate

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Name
Meglumine antimoniate
Accession Number
DB13732
Type
Small Molecule
Groups
Experimental, Investigational
Description
Not Available
Structure
Thumb
Synonyms
  • Antimoniato de meglumina
  • Meglumine antimonate
  • Meglumine antimoniate
Categories
UNII
75G4TW236W
CAS number
133-51-7
Weight
Average: 365.98
Monoisotopic: 365.00705
Chemical Formula
C7H18NO8Sb
InChI Key
XOGYVDXPYVPAAQ-SESJOKTNSA-M
InChI
InChI=1S/C7H17NO5.H2O.2O.Sb/c1-8-2-4(10)6(12)7(13)5(11)3-9;;;;/h4-13H,2-3H2,1H3;1H2;;;/q;;;;+1/p-1/t4-,5+,6+,7+;;;;/m0..../s1
IUPAC Name
(2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentol; oxostibinic acid
SMILES
O[Sb](=O)=O.CNC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO

Pharmacology

Indication
Not Available
Pharmacodynamics
Not Available
Mechanism of action
Not Available
Absorption
Not Available
Volume of distribution
Not Available
Protein binding
Not Available
Metabolism
Not Available
Route of elimination
Not Available
Half life
Not Available
Clearance
Not Available
Toxicity
Not Available
Affected organisms
Not Available
Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
Not Available
Food Interactions
Not Available

References

General References
Not Available
External Links
ChemSpider
58479
ChEMBL
CHEMBL239129
Wikipedia
Meglumine_antimoniate
ATC Codes
P01CB01 — Meglumine antimonate

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
2CompletedTreatmentLeishmaniasis / Leishmaniasis, Cutaneous / Leishmaniasis; American1
2RecruitingTreatmentLeishmaniasis1
2, 3CompletedTreatmentLeishmaniasis, Cutaneous2
2, 3RecruitingTreatmentMucocutaneous Leishmaniasis1
2, 3TerminatedTreatmentLeishmaniasis, Cutaneous1
3CompletedTreatmentLeishmaniasis, Cutaneous1
3TerminatedTreatmentLeishmaniasis, Cutaneous2
3Unknown StatusTreatmentLeishmaniasis, Cutaneous1
4CompletedTreatmentLeishmaniasis, Cutaneous1
4CompletedTreatmentLocalized Cutaneous Leishmaniasis1
4CompletedTreatmentVisceral Leishmaniasis1
Not AvailableCompletedTreatmentLeishmaniasis, Cutaneous1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility240.0 mg/mLALOGPS
logP-2.4ALOGPS
logP-3.4ChemAxon
logS0.09ALOGPS
pKa (Strongest Acidic)12.65ChemAxon
pKa (Strongest Basic)9.11ChemAxon
Physiological Charge1ChemAxon
Hydrogen Acceptor Count6ChemAxon
Hydrogen Donor Count6ChemAxon
Polar Surface Area113.18 Å2ChemAxon
Rotatable Bond Count6ChemAxon
Refractivity44.84 m3·mol-1ChemAxon
Polarizability19.52 Å3ChemAxon
Number of Rings0ChemAxon
Bioavailability1ChemAxon
Rule of FiveNoChemAxon
Ghose FilterNoChemAxon
Veber's RuleNoChemAxon
MDDR-like RuleNoChemAxon
Predicted ADMET features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
SpectrumSpectrum TypeSplash Key
Predicted MS/MS Spectrum - 10V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 20V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 40V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 10V, Negative (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 20V, Negative (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 40V, Negative (Annotated)Predicted LC-MS/MSNot Available

Taxonomy

Description
This compound belongs to the class of organic compounds known as hexoses. These are monosaccharides in which the sugar unit is a is a six-carbon containing moeity.
Kingdom
Organic compounds
Super Class
Organic oxygen compounds
Class
Organooxygen compounds
Sub Class
Carbohydrates and carbohydrate conjugates
Direct Parent
Hexoses
Alternative Parents
Organic antimonates / 1,3-aminoalcohols / Secondary alcohols / Organic antimony salts / 1,2-aminoalcohols / Polyols / Dialkylamines / Primary alcohols / Organopnictogen compounds / Organic oxides
show 1 more
Substituents
Hexose monosaccharide / Organic antimonate / 1,3-aminoalcohol / 1,2-aminoalcohol / Organic antimony salt / Secondary alcohol / Secondary aliphatic amine / Polyol / Organic metal salt / Secondary amine
show 11 more
Molecular Framework
Aliphatic acyclic compounds
External Descriptors
Not Available

Drug created on June 23, 2017 14:47 / Updated on November 05, 2018 17:50