Mebhydrolin

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Name
Mebhydrolin
Accession Number
DB13808
Type
Small Molecule
Groups
Experimental
Description
Not Available
Structure
Thumb
Synonyms
Not Available
Categories
UNII
9SUK9B7XVY
CAS number
524-81-2
Weight
Average: 276.383
Monoisotopic: 276.162648652
Chemical Formula
C19H20N2
InChI Key
FQQIIPAOSKSOJM-UHFFFAOYSA-N
InChI
InChI=1S/C19H20N2/c1-20-12-11-19-17(14-20)16-9-5-6-10-18(16)21(19)13-15-7-3-2-4-8-15/h2-10H,11-14H2,1H3
IUPAC Name
5-benzyl-2-methyl-1H,2H,3H,4H,5H-pyrido[4,3-b]indole
SMILES
CN1CCC2=C(C1)C1=CC=CC=C1N2CC1=CC=CC=C1

Pharmacology

Indication
Not Available
Pharmacodynamics
Not Available
Mechanism of action
Not Available
Absorption
Not Available
Volume of distribution
Not Available
Protein binding
Not Available
Metabolism
Not Available
Route of elimination
Not Available
Half life
Not Available
Clearance
Not Available
Toxicity
Not Available
Affected organisms
Not Available
Pathways
PathwayCategory
Mebhydrolin H1-Antihistamine ActionDrug action
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
DrugInteraction
DeoxyepinephrineThe therapeutic efficacy of Deoxyepinephrine can be increased when used in combination with Mebhydrolin.
DroxidopaThe therapeutic efficacy of Droxidopa can be increased when used in combination with Mebhydrolin.
EphedrineThe therapeutic efficacy of Ephedrine can be increased when used in combination with Mebhydrolin.
EpinephrineThe therapeutic efficacy of Epinephrine can be increased when used in combination with Mebhydrolin.
IbopamineThe therapeutic efficacy of Ibopamine can be increased when used in combination with Mebhydrolin.
LevonordefrinThe therapeutic efficacy of Levonordefrin can be increased when used in combination with Mebhydrolin.
NorepinephrineThe therapeutic efficacy of Norepinephrine can be increased when used in combination with Mebhydrolin.
ProtokylolThe therapeutic efficacy of Protokylol can be increased when used in combination with Mebhydrolin.
RacepinephrineThe therapeutic efficacy of Racepinephrine can be increased when used in combination with Mebhydrolin.
TheodrenalineThe therapeutic efficacy of Theodrenaline can be increased when used in combination with Mebhydrolin.
Additional Data Available
  • Extended Description
    Extended Description

    Extended description of the mechanism of action and particular properties of each drug interaction.

    Learn more
  • Severity
    Severity

    A severity rating for each drug interaction, from minor to major.

    Learn more
  • Evidence Level
    Evidence Level

    A rating for the strength of the evidence supporting each drug interaction.

    Learn more
  • Action
    Action

    An effect category for each drug interaction. Know how this interaction affects the subject drug.

    Learn more
Food Interactions
Not Available

References

General References
Not Available
External Links
Human Metabolome Database
HMDB0240237
ChemSpider
21129
RxNav
29411
ChEBI
135144
ChEMBL
CHEMBL1625607
ZINC
ZINC000000001651
Wikipedia
Mebhydrolin
ATC Codes
R06AX15 — Mebhydrolin

Clinical Trials

Clinical Trials
Not Available

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility0.0367 mg/mLALOGPS
logP3.69ALOGPS
logP3.69ChemAxon
logS-3.9ALOGPS
pKa (Strongest Basic)7.2ChemAxon
Physiological Charge1ChemAxon
Hydrogen Acceptor Count1ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area8.17 Å2ChemAxon
Rotatable Bond Count2ChemAxon
Refractivity88.49 m3·mol-1ChemAxon
Polarizability32.54 Å3ChemAxon
Number of Rings4ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleNoChemAxon
Predicted ADMET features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
SpectrumSpectrum TypeSplash Key
Predicted GC-MS Spectrum - GC-MSPredicted GC-MSNot Available
Predicted MS/MS Spectrum - 10V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 20V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 40V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 10V, Negative (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 20V, Negative (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 40V, Negative (Annotated)Predicted LC-MS/MSNot Available

Taxonomy

Description
This compound belongs to the class of organic compounds known as n-alkylindoles. These are compounds containing an indole moiety that carries an alkyl chain at the 1-position.
Kingdom
Organic compounds
Super Class
Organoheterocyclic compounds
Class
Indoles and derivatives
Sub Class
N-alkylindoles
Direct Parent
N-alkylindoles
Alternative Parents
3-alkylindoles / Aralkylamines / Substituted pyrroles / Benzene and substituted derivatives / Heteroaromatic compounds / Trialkylamines / Azacyclic compounds / Organopnictogen compounds / Hydrocarbon derivatives
Substituents
N-alkylindole / 3-alkylindole / Indole / Aralkylamine / Monocyclic benzene moiety / Substituted pyrrole / Benzenoid / Pyrrole / Heteroaromatic compound / Tertiary aliphatic amine
Molecular Framework
Aromatic heteropolycyclic compounds
External Descriptors
Not Available

Drug created on June 23, 2017 14:49 / Updated on June 12, 2020 10:53

Logo pink
Are you a
new drug developer?
Contact us to learn more about our customized products and solutions.
Logo pink
Stay in the know!
As part of our commitment to providing the most up-to-date drug information, we will be releasing #DrugBankUpdates with our newly added curated drug pages.
#DrugBankUpdates