Magnesium phosphate

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Summary

Magnesium phosphate is a supplement indicated in the treatment of magnesium deficiency.

Generic Name
Magnesium phosphate
DrugBank Accession Number
DB13862
Background

Not Available

Type
Small Molecule
Groups
Experimental
Structure
Weight
Average: 262.858
Monoisotopic: 261.861965694
Chemical Formula
Mg3O8P2
Synonyms
  • Magnesium phosphate (3:2)
  • Magnesium phosphate anhydrous
  • Magnesium phosphate, tribasic
  • Magnesium phosphate, tribasic, anhydrous
  • Phosphoric acid, magnesium salt (2:3)
  • Tertiary magnesium phosphate
  • Trimagnesium phosphate
External IDs
  • E-343(III)
  • INS NO.343(III)
  • INS-343(III)

Pharmacology

Indication

Not Available

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Associated Conditions
Indication TypeIndicationCombined Product DetailsApproval LevelAge GroupPatient CharacteristicsDose Form
Used in combination to treatMagnesium deficiencyCombination Product in combination with: Magnesium citrate (DB11110)••• ••••••••••
Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
DrugInteraction
AtracuriumThe therapeutic efficacy of Atracurium can be increased when used in combination with Magnesium phosphate.
Atracurium besylateThe therapeutic efficacy of Atracurium besylate can be increased when used in combination with Magnesium phosphate.
Botulinum toxin type AThe therapeutic efficacy of Botulinum toxin type A can be increased when used in combination with Magnesium phosphate.
Botulinum toxin type BThe risk or severity of adverse effects can be increased when Magnesium phosphate is combined with Botulinum toxin type B.
CapreomycinThe risk or severity of neuromuscular blockade can be increased when Capreomycin is combined with Magnesium phosphate.
Food Interactions
Not Available

Products

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Product Ingredients
IngredientUNIICASInChI Key
Magnesium phosphate dibasic trihydrateHF539G9L3Q7782-75-4OKIWLDVQGKRUNR-UHFFFAOYSA-L
Magnesium phosphate pentahydrate453COF781710233-87-1QZYXGKYJDBUYES-UHFFFAOYSA-H
Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
BIOMAGNESINMagnesium phosphate dibasic trihydrate (265 mg/1) + Magnesium (42.9 mg/1)LozengeOral2006-07-01Not applicableGermany flag
BIOMAGNESINMagnesium phosphate dibasic trihydrate (265 mg/1) + Magnesium (42.9 mg/1)LozengeOral2006-07-01Not applicableGermany flag
BLACKMORES EXECUTIVE B TABLETMagnesium phosphate (175 mg) + Ascorbic acid (180 mg) + Biotin (50 µg) + Cyanocobalamin (10 µg) + Folic acid (200 mcg) + Nicotinamide (60 mg) + Pantothenic acid (20 mg) + Potassium sulfate (75 mg) + Pyridoxine hydrochloride (10 mg) + Riboflavin (8.5 mg) + Thiamine mononitrate (7.5 mg) + Zinc sulfate (15 mg)TabletOralBLACKMORES (MALAYSIA) SDN. BHD.2020-09-08Not applicableMalaysia flag

Categories

ATC Codes
B05XA10 — Magnesium phosphate
Drug Categories
Chemical TaxonomyProvided by Classyfire
Description
This compound belongs to the class of inorganic compounds known as alkaline earth metal phosphates. These are inorganic compounds in which the largest oxoanion is phosphate, and in which the heaviest atom not in an oxoanion is an alkaline earth metal.
Kingdom
Inorganic compounds
Super Class
Mixed metal/non-metal compounds
Class
Alkaline earth metal oxoanionic compounds
Sub Class
Alkaline earth metal phosphates
Direct Parent
Alkaline earth metal phosphates
Alternative Parents
Inorganic salts / Inorganic oxides
Substituents
Alkaline earth metal phosphate / Inorganic oxide / Inorganic salt
Molecular Framework
Not Available
External Descriptors
Not Available
Affected organisms
Not Available

Chemical Identifiers

UNII
XMK14ETW2D
CAS number
7757-87-1
InChI Key
GVALZJMUIHGIMD-UHFFFAOYSA-H
InChI
InChI=1S/3Mg.2H3O4P/c;;;2*1-5(2,3)4/h;;;2*(H3,1,2,3,4)/q3*+2;;/p-6
IUPAC Name
trimagnesium(2+) diphosphate
SMILES
[Mg++].[Mg++].[Mg++].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O

References

General References
  1. DIMDI Product Information: BIOMAGNESIN (magnesium citrate and magnesium phosphate ) oral lozenge [Link]
ChemSpider
22847
RxNav
29164
ChEMBL
CHEMBL2106873
Wikipedia
Magnesium_phosphate

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
LozengeOral
TabletOral
Prices
Not Available
Patents
Not Available

Properties

State
Solid
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
logP-1Chemaxon
pKa (Strongest Acidic)1.8Chemaxon
Physiological Charge-2Chemaxon
Hydrogen Acceptor Count4Chemaxon
Hydrogen Donor Count0Chemaxon
Polar Surface Area86.25 Å2Chemaxon
Rotatable Bond Count0Chemaxon
Refractivity11.29 m3·mol-1Chemaxon
Polarizability4.93 Å3Chemaxon
Number of Rings0Chemaxon
Bioavailability1Chemaxon
Rule of FiveYesChemaxon
Ghose FilterNoChemaxon
Veber's RuleNoChemaxon
MDDR-like RuleNoChemaxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Not Available
Chromatographic Properties
Collision Cross Sections (CCS)
AdductCCS Value (Å2)Source typeSource
[M-H]-105.5384532
predicted
DarkChem Lite v0.1.0

Drug created at June 26, 2017 20:08 / Updated at May 21, 2021 10:23