Showing BioInteractions for D-alpha-Tocopherol acetate (DB14002)
BioInteractor utilizes data on drug-target, -enzyme and -transporter associations to provide insight on drug-drug interactions. It allows you to identify, for instance, which drugs act similarly on the same target. Such drugs may have additive pharmacodynamic effects if given concomitantly. Conversely, two drugs may antagonize the beneficial effects of each other by having opposite actions on a specific drug target. BioInteractor uses ranked drug-enzyme association information to predict enzyme-mediated drug interactions that may be clinically relevant.
| Interacting Group | Interacting Drugs | |
|---|---|---|
| D-alpha-Tocopherol acetate is a Glutathione S-transferase A2 inducer | ||
| 1 | Glutathione S-transferase A2 inhibitors | Chloroquine, Clofibrate, Etacrynic acid |
| 2 | Glutathione S-transferase A2 substrates | Azathioprine, Busulfan, Glutathione |
| 3 | Glutathione S-transferase A2 inducers | alpha-Tocopherol succinate, Vitamin E |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| D-alpha-Tocopherol acetate is a Glutathione S-transferase P inhibitor | ||
| 1 | Glutathione S-transferase P inhibitors | alpha-Tocopherol succinate, Clomipramine, Curcumin, Etacrynic acid, Exisulind, Vitamin E |
| 2 | Glutathione S-transferase P substrates | Acetaminophen, Busulfan, Carboplatin, Chlorambucil, Cisplatin, Etoposide, Oxaliplatin |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| D-alpha-Tocopherol acetate is a Glutathione S-transferase omega-1 inhibitor | ||
| 1 | Glutathione S-transferase omega-1 inhibitors | alpha-Tocopherol succinate, Vitamin E |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| D-alpha-Tocopherol acetate is a Glutathione S-transferase Mu 3 inducer | ||
| 1 | Glutathione S-transferase Mu 3 inducers | alpha-Tocopherol succinate, Vitamin E |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| D-alpha-Tocopherol acetate is a Glutamate--cysteine ligase catalytic subunit inducer | ||
| 1 | Glutamate--cysteine ligase catalytic subunit substrates | Glutamic acid |
| 2 | Glutamate--cysteine ligase catalytic subunit inducers | alpha-Tocopherol succinate, Vitamin E |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| D-alpha-Tocopherol acetate is a NAD(P)H dehydrogenase [quinone] 1 inducer | ||
| 1 | NAD(P)H dehydrogenase [quinone] 1 inhibitors | Cannabidiol, Dicoumarol |
| 2 | NAD(P)H dehydrogenase [quinone] 1 inducers | alpha-Tocopherol succinate, Vitamin E |
| 3 | NAD(P)H dehydrogenase [quinone] 1 substrates | Carboplatin, Cisplatin, Doxorubicin, Oxaliplatin, Phenytoin |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| D-alpha-Tocopherol acetate is a Heme oxygenase 1 inducer | ||
| 1 | Heme oxygenase 1 inducers | alpha-Tocopherol succinate, Polaprezinc, Vitamin E |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| D-alpha-Tocopherol acetate is a Superoxide dismutase [Cu-Zn] inducer | ||
| 1 | Superoxide dismutase [Cu-Zn] inducers | alpha-Tocopherol succinate, Polaprezinc, Vitamin E |
| 2 | Superoxide dismutase [Cu-Zn] substrates | Cisplatin, Oxaliplatin |
| 3 | Superoxide dismutase [Cu-Zn] inhibitors | Cannabidiol, Carboplatin, Medical Cannabis, Nabiximols |
| 4 | Superoxide dismutase [Cu-Zn] cofactors | Copper, Zinc chloride, Zinc sulfate, unspecified form |
| 5 | Superoxide dismutase [Cu-Zn] ligands | Zinc acetate |