Sodium bisulfite

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Logo pink
Are you a
new drug developer?
Contact us to learn more about our customized products and solutions.
Name
Sodium bisulfite
Accession Number
DB14015
Type
Small Molecule
Groups
Approved
Description

Sodium bisulfite has been used externally for parasitic skin diseases and as gastrointestinal antiseptic.

Structure
Thumb
Synonyms
  • Bisulfite de sodium
  • Natriumbisulfit
  • Natriumhydrogensulfit
  • primäres Natriumsulfit
  • saures Natriumsulfit
  • sodium bisulphite
  • sodium hydrogen sulfite
  • sodium hydrogensulfite
External IDs
E222
Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing End
Nephramine Liq IVSodium bisulfite (40 mg) + Histidine (250 mg) + Isoleucine (560 mg) + L-Cysteine (13 mg) + L-Leucine (880 mg) + L-Lysine (640 mg) + L-Phenylalanine (880 mg) + L-Threonine (400 mg) + L-Tryptophan (200 mg) + L-Valine (640 mg) + Racemethionine (880 mg)SolutionIntravenousB. Braun Medical Inc.1993-12-31Not applicableCanada
Categories
UNII
TZX5469Z6I
CAS number
7631-90-5
Weight
Average: 104.061
Monoisotopic: 103.954409263
Chemical Formula
HNaO3S
InChI Key
DWAQJAXMDSEUJJ-UHFFFAOYSA-M
InChI
InChI=1S/Na.H2O3S/c;1-4(2)3/h;(H2,1,2,3)/q+1;/p-1
IUPAC Name
sodium hydrogen sulfite
SMILES
[Na+].OS([O-])=O

Pharmacology

Indication
Not Available
Associated Therapies
Pharmacodynamics
Not Available
Mechanism of action
Not Available
Additional Data Available
Adverse Effects

Comprehensive structured data on known drug adverse effects with statistical prevalence. MedDRA and ICD10 ids are provided for adverse effect conditions and symptoms.

Learn more
Additional Data Available
Contraindications

Structured data covering drug contraindications. Each contraindication describes a scenario in which the drug is not to be used. Includes restrictions on co-administration, contraindicated populations, and more.

Learn more
Additional Data Available
Blackbox Warnings

Structured data representing warnings from the black box section of drug labels. These warnings cover important and dangerous risks, contraindications, or adverse effects.

Learn more
Absorption
Not Available
Volume of distribution
Not Available
Protein binding
Not Available
Metabolism
Not Available
Route of elimination
Not Available
Half life
Not Available
Clearance
Not Available
Toxicity
Not Available
Affected organisms
Not Available
Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
DrugInteraction
CisplatinThe therapeutic efficacy of Cisplatin can be decreased when used in combination with Sodium bisulfite.
Additional Data Available
  • Extended Description
    Extended Description

    Extended description of the mechanism of action and particular properties of each drug interaction.

    Learn more
  • Severity
    Severity

    A severity rating for each drug interaction, from minor to major.

    Learn more
  • Evidence Level
    Evidence Level

    A rating for the strength of the evidence supporting each drug interaction.

    Learn more
  • Action
    Evidence Level

    An effect category for each drug interaction. Know how this interaction affects the subject drug.

    Learn more
Food Interactions
Not Available

References

General References
Not Available
External Links
ChemSpider
571016
ChEBI
26709
ChEMBL
CHEMBL1689285
Wikipedia
Sodium_bisulfite

Clinical Trials

Clinical Trials
Not Available

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage forms
FormRouteStrength
SolutionIntravenous
Prices
Not Available
Patents
Not Available

Properties

State
Solid
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
logP-1.2ChemAxon
pKa (Strongest Acidic)1.7ChemAxon
Physiological Charge-1ChemAxon
Hydrogen Acceptor Count3ChemAxon
Hydrogen Donor Count1ChemAxon
Polar Surface Area60.36 Å2ChemAxon
Rotatable Bond Count0ChemAxon
Refractivity11.21 m3·mol-1ChemAxon
Polarizability5.43 Å3ChemAxon
Number of Rings0ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterNoChemAxon
Veber's RuleNoChemAxon
MDDR-like RuleNoChemAxon
Predicted ADMET features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Not Available

Taxonomy

Classification
Not classified

Drug created on April 25, 2018 16:30 / Updated on May 01, 2019 11:55