Magnesium stearate

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

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Name
Magnesium stearate
Accession Number
DB14077
Type
Small Molecule
Groups
Investigational
Description
Not Available
Structure
Thumb
Synonyms
  • Dibasic magnesium stearate
  • Magnesium distearate
  • Magnesium octadecanoate
  • Octadecanoic acid, magnesium salt
  • Stearic acid, magnesium salt
External IDs
SM 1000
Over the Counter Products
NameDosageStrengthRouteLabellerMarketing StartMarketing End
DayclingTablet5 mg/1VaginalIstk32017-10-24Not applicableUs
Additional Data Available
  • Application Number
    Application Number

    A unique ID assigned by the FDA when a product is submitted for approval by the labeller.

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  • Product Code
    Product Code

    A governmentally-recognized ID which uniquely identifies the product within its regulatory market.

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Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing End
Medi Megaton 2080Magnesium stearate (0.005 g/100g) + Glycerin (0.002 g/100g) + Saw palmetto (0.01 g/100g) + Silicon dioxide (0.01 g/100g) + Titanium dioxide (0.001 g/100g) + Zinc oxide (0.0146 g/100g)PowderTopicalMbg Inc (Korea Institute of Science Development)2016-10-162017-10-16Us
Medi Megaton 2080Magnesium stearate (0.005 g/100g) + Glycerin (0.002 g/100g) + Saw palmetto (0.01 g/100g) + Silicon dioxide (0.01 g/100g) + Titanium dioxide (0.001 g/100g) + Zinc oxide (0.0146 g/100g)PowderTopicalMbg Inc (Korea Institute of Science Development)2016-10-152017-10-15Us
Unapproved/Other Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing End
DayclingMagnesium stearate (5 mg/1)TabletVaginalIstk32017-10-24Not applicableUs
Medi Megaton 2080Magnesium stearate (0.005 g/100g) + Glycerin (0.002 g/100g) + Saw palmetto (0.01 g/100g) + Silicon dioxide (0.01 g/100g) + Titanium dioxide (0.001 g/100g) + Zinc oxide (0.0146 g/100g)PowderTopicalMbg Inc (Korea Institute of Science Development)2016-10-162017-10-16Us
Medi Megaton 2080Magnesium stearate (0.005 g/100g) + Glycerin (0.002 g/100g) + Saw palmetto (0.01 g/100g) + Silicon dioxide (0.01 g/100g) + Titanium dioxide (0.001 g/100g) + Zinc oxide (0.0146 g/100g)PowderTopicalMbg Inc (Korea Institute of Science Development)2016-10-152017-10-15Us
Categories
UNII
70097M6I30
CAS number
557-04-0
Weight
Average: 591.244
Monoisotopic: 590.512452626
Chemical Formula
C36H70MgO4
InChI Key
HQKMJHAJHXVSDF-UHFFFAOYSA-L
InChI
InChI=1S/2C18H36O2.Mg/c2*1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20;/h2*2-17H2,1H3,(H,19,20);/q;;+2/p-2
IUPAC Name
magnesium(2+) dioctadecanoate
SMILES
[Mg++].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O

Pharmacology

Indication
Not Available
Pharmacodynamics
Not Available
Mechanism of action
Not Available
Additional Data Available
Adverse Effects

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Additional Data Available
Contraindications

Structured data covering drug contraindications. Each contraindication describes a scenario in which the drug is not to be used. Includes restrictions on co-administration, contraindicated populations, and more.

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Additional Data Available
Blackbox Warnings

Structured data representing warnings from the black box section of drug labels. These warnings cover important and dangerous risks, contraindications, or adverse effects.

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Absorption
Not Available
Volume of distribution
Not Available
Protein binding
Not Available
Metabolism
Not Available
Route of elimination
Not Available
Half life
Not Available
Clearance
Not Available
Toxicity
Not Available
Affected organisms
Not Available
Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
Not Available
Food Interactions
Not Available

References

General References
Not Available
External Links
KEGG Drug
D02189
ChemSpider
10704
ChEBI
9254
ChEMBL
CHEMBL2106633
Wikipedia
Magnesium_stearate

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
1CompletedSupportive CareStable COPD Patients1
1CompletedTreatmentAsthma Bronchial / Chronic Obstructive Pulmonary Disease (COPD)1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage forms
FormRouteStrength
TabletVaginal5 mg/1
PowderTopical
Prices
Not Available
Patents
Not Available

Properties

State
Solid
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility1.13e-05 mg/mLALOGPS
logP10.89ALOGPS
logP7.15ChemAxon
logS-7.7ALOGPS
pKa (Strongest Acidic)4.95ChemAxon
Physiological Charge-1ChemAxon
Hydrogen Acceptor Count2ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area40.13 Å2ChemAxon
Rotatable Bond Count32ChemAxon
Refractivity97.12 m3·mol-1ChemAxon
Polarizability38.18 Å3ChemAxon
Number of Rings0ChemAxon
Bioavailability0ChemAxon
Rule of FiveNoChemAxon
Ghose FilterNoChemAxon
Veber's RuleNoChemAxon
MDDR-like RuleNoChemAxon
Predicted ADMET features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Not Available

Taxonomy

Classification
Not classified

Drug created on June 17, 2018 10:58 / Updated on November 02, 2018 07:50