1,2-Distearoyllecithin

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Name
1,2-Distearoyllecithin
Accession Number
DB14099
Type
Small Molecule
Groups
Approved, Experimental
Description
Not Available
Structure
Thumb
Synonyms
  • 1,2-Distearoyl-sn-glycero-3-phosphocholine
  • 1,2-Distearoylphosphatidylcholine
  • Dioctadecanoyl phosphatidylcholine
  • Dioctadecanoyllecithin
  • Distearoyl-DL-phosphatidylcholine
Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing End
LumaSon1,2-Distearoyllecithin (.19 mg/1mg) + Sodium 1,2-Dipalmitoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (.19 mg/1mg) + Sulfur hexafluoride (60.7 mg/1mg)KitBracco Diagnostics, Inc2015-01-15Not applicableUs
Categories
UNII
EAG959U971
CAS number
4539-70-2
Weight
Average: 790.161
Monoisotopic: 789.624755796
Chemical Formula
C44H88NO8P
InChI Key
NRJAVPSFFCBXDT-UHFFFAOYSA-N
InChI
InChI=1S/C44H88NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-43(46)50-40-42(41-52-54(48,49)51-39-38-45(3,4)5)53-44(47)37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h42H,6-41H2,1-5H3
IUPAC Name
(2-{[2,3-bis(octadecanoyloxy)propyl phosphono]oxy}ethyl)trimethylazanium
SMILES
CCCCCCCCCCCCCCCCCC(=O)OCC(COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCCCCCCCCCCCCCCCC

Pharmacology

Indication
Not Available
Pharmacodynamics
Not Available
Mechanism of action
Not Available
Absorption
Not Available
Volume of distribution
Not Available
Protein binding
Not Available
Metabolism
Not Available
Route of elimination
Not Available
Half life
Not Available
Clearance
Not Available
Toxicity
Not Available
Affected organisms
Not Available
Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
Not Available
Food Interactions
Not Available

References

General References
Not Available
External Links
ChemSpider
58655
ChEMBL
CHEMBL113644

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
2Not Yet RecruitingDiagnosticAppendicitis Acute1
4Not Yet RecruitingDiagnosticVesico-Ureteral Reflux1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage forms
FormRouteStrength
Kit
Prices
Not Available
Patents
Patent NumberPediatric ExtensionApprovedExpires (estimated)
US5686060No1997-11-112017-11-11Us

Properties

State
Solid
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility2.16e-05 mg/mLALOGPS
logP5.92ALOGPS
logP9.89ChemAxon
logS-7.6ALOGPS
pKa (Strongest Acidic)1.86ChemAxon
pKa (Strongest Basic)-6.7ChemAxon
Physiological Charge0ChemAxon
Hydrogen Acceptor Count4ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area111.19 Å2ChemAxon
Rotatable Bond Count44ChemAxon
Refractivity234.27 m3·mol-1ChemAxon
Polarizability99.73 Å3ChemAxon
Number of Rings0ChemAxon
Bioavailability0ChemAxon
Rule of FiveNoChemAxon
Ghose FilterNoChemAxon
Veber's RuleNoChemAxon
MDDR-like RuleNoChemAxon
Predicted ADMET features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Not Available

Taxonomy

Classification
Not classified

Drug created on June 18, 2018 12:57 / Updated on November 02, 2018 07:50