Sodium 1,2-Dipalmitoyl-sn-glycero-3-phospho-(1'-rac-glycerol)

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Name
Sodium 1,2-Dipalmitoyl-sn-glycero-3-phospho-(1'-rac-glycerol)
Accession Number
DB14105
Description
Not Available
Type
Small Molecule
Groups
Approved, Experimental
Structure
Thumb
Weight
Average: 744.964
Monoisotopic: 744.49172986
Chemical Formula
C38H74NaO10P
Synonyms
  • 1,2-dipalmitoyl-sn-glycero-3-phosphorylglycerol sodium salt
  • L-DPPG-Na
  • R-DPPG-Na
External IDs
  • MG-6060LS

Pharmacology

Indication
Not Available
Contraindications & Blackbox Warnings
Learn about our commercial Contraindications & Blackbox Warnings data.
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Pharmacodynamics
Not Available
Mechanism of action
Not Available
Absorption
Not Available
Volume of distribution
Not Available
Protein binding
Not Available
Metabolism
Not Available
Route of elimination
Not Available
Half-life
Not Available
Clearance
Not Available
Adverse Effects
Learn about our commercial Adverse Effects data.
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Toxicity
Not Available
Affected organisms
Not Available
Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
No interactions found.

Products

Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
LumaSonSodium 1,2-Dipalmitoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (.19 mg/1mg) + 1,2-Distearoyllecithin (.19 mg/1mg) + Sulfur hexafluoride (60.7 mg/1mg)Intravenous; IntravesicalBracco Diagnostics Inc2015-01-15Not applicableUs
LumaSonSodium 1,2-Dipalmitoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (.19 mg/1mg) + 1,2-Distearoyllecithin (.19 mg/1mg) + Sulfur hexafluoride (60.7 mg/1mg)KitIntravenous; IntravesicalBracco Suisse SA2015-01-15Not applicableUs

Categories

Drug Categories
Not Available
Classification
Not classified

Chemical Identifiers

UNII
841B886EJ7
CAS number
200880-41-7
InChI Key
LDWIWSHBGAIIMV-ODZMYOIVSA-M
InChI
InChI=1S/C38H75O10P.Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-37(41)45-33-36(34-47-49(43,44)46-32-35(40)31-39)48-38(42)30-28-26-24-22-20-18-16-14-12-10-8-6-4-2;/h35-36,39-40H,3-34H2,1-2H3,(H,43,44);/q;+1/p-1/t35?,36-;/m1./s1
IUPAC Name
sodium (2R)-1-[(2,3-dihydroxypropyl phosphono)oxy]-3-(hexadecanoyloxy)propan-2-yl hexadecanoate
SMILES
[Na+].[H][C@@](COC(=O)CCCCCCCCCCCCCCC)(COP([O-])(=O)OCC(O)CO)OC(=O)CCCCCCCCCCCCCCC

References

General References
Not Available
ChemSpider
29763754
RxNav
1599275

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
4Enrolling by InvitationDiagnosticCrohn's Disease (CD)1
4RecruitingDiagnosticAbdominal Injuries / Accidental Fall / Motor Vehicle Injury / Physical Abuse1
4RecruitingDiagnosticRenal Malignant Tumor1
4RecruitingDiagnosticTrauma Abdomen1
4TerminatedDiagnosticLiver Biopsy1
4WithdrawnDiagnosticBone Marrow Transplant Complications / Sinusoidal Obstruction Syndrome / Stem Cell Transplant Complications / Veno Occlusive Disease, Hepatic1
4WithdrawnDiagnosticNeonatal Post-Hemorrhagic Hydrocephalus1
3CompletedDiagnosticCoronary Artery Disease (CAD)2
3TerminatedDiagnosticHeart Diseases1
2Active Not RecruitingBasic ScienceCarotid Artery Plaque1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
KitIntravenous; Intravesical
Prices
Not Available
Patents
Patent NumberPediatric ExtensionApprovedExpires (estimated)Region
US5686060No1997-11-112017-11-11Us
US10232061No2019-03-192038-07-06Us
US10335502No2019-07-022038-07-06Us
Additional Data Available
  • Filed On
    Filed On

    The date on which a patent was filed with the relevant government.

    Learn more

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility0.000119 mg/mLALOGPS
logP8.32ALOGPS
logP10.94ChemAxon
logS-6.8ALOGPS
pKa (Strongest Acidic)1.89ChemAxon
pKa (Strongest Basic)-3ChemAxon
Physiological Charge-1ChemAxon
Hydrogen Acceptor Count6ChemAxon
Hydrogen Donor Count2ChemAxon
Polar Surface Area151.65 Å2ChemAxon
Rotatable Bond Count40ChemAxon
Refractivity194.19 m3·mol-1ChemAxon
Polarizability88.81 Å3ChemAxon
Number of Rings0ChemAxon
Bioavailability0ChemAxon
Rule of FiveNoChemAxon
Ghose FilterNoChemAxon
Veber's RuleNoChemAxon
MDDR-like RuleNoChemAxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Not Available

Drug created on June 21, 2018 10:23 / Updated on June 12, 2020 10:53

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