Ginsenosides

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name
Ginsenosides
DrugBank Accession Number
DB14152
Background

Dammarane type triterpene saponins based mainly on the aglycones, protopanaxadiol and protopanaxatriol.

Type
Small Molecule
Groups
Experimental
Structure
Weight
Average: 444.744
Monoisotopic: 444.396730914
Chemical Formula
C30H52O2
Synonyms
  • Ginseng root-neutral saponins
  • Ginsenoside
  • Neutral saponins of panax ginseng root
External IDs
  • BM-RE60
  • KG 135

Pharmacology

Indication

Not Available

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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Products

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Over the Counter Products
NameDosageStrengthRouteLabellerMarketing StartMarketing EndRegionImage
Qwg-1000Liquid0.04 g/100mLTopicalInstitute of Quantum Bioscience2022-11-20Not applicableUS flag
Ruby Cell 4u Rg3 PureSoap0.7 g/100gTopicalDasan E&T Co., Ltd.2014-12-012017-12-01US flag
Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
Herbal Iron Brilliant Performance for Brightening and Wrinkle FreeGinsenosides (0.05 g/100mL) + Ginsenosides (0.05 g/100mL) + Ginsenosides (0.1 g/100mL) + Ginsenosides (0.1 g/100g) + Adenosine (0.04 g/100mL) + Adenosine (0.04 g/100mL) + Adenosine (0.04 g/100mL) + Adenosine (0.04 g/100g)KitTopicalBtgin Co.,Ltd2017-03-27Not applicableUS flag
Herbal Iron Brilliant Performance for Brightening and Wrinkle FreeGinsenosides (0.05 g/100mL) + Ginsenosides (0.05 g/100mL) + Ginsenosides (0.1 g/100mL) + Ginsenosides (0.1 g/100g) + Adenosine (0.04 g/100mL) + Adenosine (0.04 g/100mL) + Adenosine (0.04 g/100mL) + Adenosine (0.04 g/100g)KitTopicalBtgin Co.,Ltd2017-03-27Not applicableUS flag
Herbal Iron Brilliant Performance for Brightening and Wrinkle FreeGinsenosides (0.05 g/100mL) + Ginsenosides (0.05 g/100mL) + Ginsenosides (0.1 g/100mL) + Ginsenosides (0.1 g/100g) + Adenosine (0.04 g/100mL) + Adenosine (0.04 g/100mL) + Adenosine (0.04 g/100mL) + Adenosine (0.04 g/100g)KitTopicalBtgin Co.,Ltd2017-03-27Not applicableUS flag
Herbal Iron Brilliant Performance for Brightening and Wrinkle FreeGinsenosides (0.05 g/100mL) + Ginsenosides (0.05 g/100mL) + Ginsenosides (0.1 g/100mL) + Ginsenosides (0.1 g/100g) + Adenosine (0.04 g/100mL) + Adenosine (0.04 g/100mL) + Adenosine (0.04 g/100mL) + Adenosine (0.04 g/100g)KitTopicalBtgin Co.,Ltd2017-03-27Not applicableUS flag
HERBAL IRON Enriched MoistureGinsenosides (0.05 g/100mL) + Adenosine (0.04 g/100mL)EmulsionTopicalBtgin Co.,Ltd2017-03-162017-03-27US flag
Unapproved/Other Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
Herbal Iron Brilliant Performance for Brightening and Wrinkle FreeGinsenosides (0.05 g/100mL) + Ginsenosides (0.05 g/100mL) + Ginsenosides (0.1 g/100mL) + Ginsenosides (0.1 g/100g) + Adenosine (0.04 g/100mL) + Adenosine (0.04 g/100mL) + Adenosine (0.04 g/100mL) + Adenosine (0.04 g/100g)KitTopicalBtgin Co.,Ltd2017-03-27Not applicableUS flag
Herbal Iron Brilliant Performance for Brightening and Wrinkle FreeGinsenosides (0.05 g/100mL) + Ginsenosides (0.05 g/100mL) + Ginsenosides (0.1 g/100mL) + Ginsenosides (0.1 g/100g) + Adenosine (0.04 g/100mL) + Adenosine (0.04 g/100mL) + Adenosine (0.04 g/100mL) + Adenosine (0.04 g/100g)KitTopicalBtgin Co.,Ltd2017-03-27Not applicableUS flag
Herbal Iron Brilliant Performance for Brightening and Wrinkle FreeGinsenosides (0.05 g/100mL) + Ginsenosides (0.05 g/100mL) + Ginsenosides (0.1 g/100mL) + Ginsenosides (0.1 g/100g) + Adenosine (0.04 g/100mL) + Adenosine (0.04 g/100mL) + Adenosine (0.04 g/100mL) + Adenosine (0.04 g/100g)KitTopicalBtgin Co.,Ltd2017-03-27Not applicableUS flag
Herbal Iron Brilliant Performance for Brightening and Wrinkle FreeGinsenosides (0.05 g/100mL) + Ginsenosides (0.05 g/100mL) + Ginsenosides (0.1 g/100mL) + Ginsenosides (0.1 g/100g) + Adenosine (0.04 g/100mL) + Adenosine (0.04 g/100mL) + Adenosine (0.04 g/100mL) + Adenosine (0.04 g/100g)KitTopicalBtgin Co.,Ltd2017-03-27Not applicableUS flag
HERBAL IRON Enriched MoistureGinsenosides (0.05 g/100mL) + Adenosine (0.04 g/100mL)EmulsionTopicalBtgin Co.,Ltd2017-03-162017-03-27US flag

Categories

Drug Categories
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
3K198YD54P
CAS number
74749-74-9
InChI Key
NLHQJXWYMZLQJY-SWIZOJJJSA-N
InChI
InChI=1S/C30H52O2/c1-20(2)10-9-16-30(8,32)22-13-18-28(6)21(22)11-12-24-27(5)17-15-25(31)26(3,4)23(27)14-19-29(24,28)7/h10,21-25,31-32H,9,11-19H2,1-8H3/t21?,22-,23-,24+,25-,27-,28+,29+,30?/m0/s1
IUPAC Name
(1S,3aR,3bR,5aR,7S,9aR,9bR)-1-(2-hydroxy-6-methylhept-5-en-2-yl)-3a,3b,6,6,9a-pentamethyl-hexadecahydro-1H-cyclopenta[a]phenanthren-7-ol
SMILES
[H][C@@]1(CC[C@]2(C)C1([H])CC[C@]1([H])[C@@]3(C)CC[C@]([H])(O)C(C)(C)[C@]3([H])CC[C@@]21C)C(C)(O)CCC=C(C)C

References

General References
Not Available
ChemSpider
2342730
RxNav
349656
Wikipedia
Ginsenoside

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
4CompletedTreatmentFatigue1
2Unknown StatusTreatmentNon-Small Cell Lung Cancer (NSCLC)1
Not AvailableCompletedNot AvailableAcute Lung Injury/Acute Respiratory Distress Syndrome (ARDS) / Apoptosis / Immunosuppression / Neutrophils / Pathogenesis1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
KitTopical
EmulsionTopical
LiquidTopical
LiquidTopical0.04 g/100mL
SoapTopical0.7 g/100g
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility0.000182 mg/mLALOGPS
logP6.39ALOGPS
logP6.84Chemaxon
logS-6.4ALOGPS
pKa (Strongest Acidic)19.49Chemaxon
pKa (Strongest Basic)-0.26Chemaxon
Physiological Charge0Chemaxon
Hydrogen Acceptor Count2Chemaxon
Hydrogen Donor Count2Chemaxon
Polar Surface Area40.46 Å2Chemaxon
Rotatable Bond Count4Chemaxon
Refractivity135.64 m3·mol-1Chemaxon
Polarizability55.91 Å3Chemaxon
Number of Rings4Chemaxon
Bioavailability1Chemaxon
Rule of FiveNoChemaxon
Ghose FilterNoChemaxon
Veber's RuleNoChemaxon
MDDR-like RuleNoChemaxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
SpectrumSpectrum TypeSplash Key
Predicted MS/MS Spectrum - 10V, Positive (Annotated)Predicted LC-MS/MSsplash10-0adj-4127900000-42fcebde6069aa61609d
Predicted MS/MS Spectrum - 10V, Negative (Annotated)Predicted LC-MS/MSsplash10-0006-0000900000-cce129f72ac44086ccea
Predicted MS/MS Spectrum - 20V, Positive (Annotated)Predicted LC-MS/MSsplash10-0f6x-9537200000-9b50503bc732b070f12f
Predicted MS/MS Spectrum - 20V, Negative (Annotated)Predicted LC-MS/MSsplash10-0006-0000900000-190c04c83febc959849c
Predicted MS/MS Spectrum - 40V, Negative (Annotated)Predicted LC-MS/MSsplash10-055f-0009800000-c37c60611c002c5927a9
Predicted MS/MS Spectrum - 40V, Positive (Annotated)Predicted LC-MS/MSsplash10-066r-4983100000-ee376a087ebee8362dfb
Predicted 1H NMR Spectrum1D NMRNot Applicable
Predicted 13C NMR Spectrum1D NMRNot Applicable
Chromatographic Properties
Collision Cross Sections (CCS)
Not Available

Drug created at June 28, 2018 21:54 / Updated at June 12, 2020 16:53