Nickel sulfate

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name

Nickel sulfate

DrugBank Accession Number

DB14180

Background

Nickel sulfate is used in allergenic testing.

Type

Small Molecule

Groups

Approved, Experimental

Structure

Similar Structures

Weight: Average: 154.756
Monoisotopic: 153.8870771
Chemical Formula: NiO₄S

Synonyms

Nickel sulfate(1:1)
Nickel sulphate
nickel(II) sulfate

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Pharmacology

Indication: Not Available
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Pharmacodynamics: Not Available
Mechanism of action: Not Available
Absorption: Not Available
Volume of distribution: Not Available
Protein binding: Not Available
Metabolism: Not Available
Route of elimination: Not Available
Half-life: Not Available
Clearance: Not Available
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Toxicity: Not Available
Pathways: Not Available
Pharmacogenomic Effects/ADRs: Not Available

Interactions

Drug Interactions: This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions: No interactions found.

Products

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Product Ingredients

Ingredient	UNII	CAS	InChI Key
Nickel sulfate hexahydrate	JC9WZ4FK68	10101-97-0	RRIWRJBSCGCBID-UHFFFAOYSA-L

Active Moieties

Name	Kind	UNII	CAS	InChI Key
Nickel cation	ionic	OIS2CXW7AM	14701-22-5	VEQPNABPJHWNSG-UHFFFAOYSA-N

Mixture Products

Name	Ingredients	Dosage	Route	Labeller	Marketing Start	Marketing End
High Potency Multivitamins & Minerals Caplets	Nickel sulfate (5 mcg) + Ascorbic acid (100 mg) + Beta carotene (2500 unit) + Biotin (45 mcg) + Calcium phosphate, dibasic (125 mg) + Calcium Phosphate (175 mg) + Cholecalciferol (400 unit) + Chromic chloride (50 mcg) + Cupric sulfate (2 mg) + Cyanocobalamin (9 mcg) + Ferrous fumarate (10 mg) + Folic acid (0.4 mg) + Magnesium oxide (100 mg) + Manganese sulfate (5 mg) + Nicotinamide (40 mg) + Pantothenic acid (10 mg) + Potassium Iodide (0.15 mg) + Potassium chloride (50 mg) + Potassium chloride (55 mg) + Pyridoxine hydrochloride (4 mg) + Riboflavin (3.4 mg) + Sodium selenate (50 mcg) + Silicon dioxide (0.01 mg) + Sodium metavanadate (10 mcg) + Sodium molybdate (50 mcg) + Stannous chloride (0.01 mg) + Thiamine mononitrate (3 mg) + Vitamin A acetate (3500 unit) + Zinc citrate (20 mg) + alpha-Tocopherol acetate (50 unit)	Tablet	Oral	Ashbury Research Corporation	Not applicable	Not applicable
Milltrium Senior Vitamin and Mineral Supplement	Nickel sulfate (5 mcg) + Ascorbic acid (60 mg) + Beta carotene (150 unit) + Biotin (30 mcg) + Calcium (200 mg) + Cholecalciferol (400 unit) + Chromium (100 mcg) + Copper (2 mg) + Cyanocobalamin (25 mcg) + Ferrous fumarate (9 mg) + Folic acid (0.2 mg) + Magnesium (100 mg) + Manganese (2.5 mg) + Nicotinamide (20 mg) + Pantothenic acid (10 mg) + Potassium (80 mg) + Potassium Iodide (0.15 mg) + Pyridoxine hydrochloride (3 mg) + Riboflavin (1.7 mg) + Sodium selenite (25 mcg) + Sodium metavanadate (10 mcg) + Sodium molybdate (25 mcg) + Thiamine hydrochloride (1.5 mg) + Vitamin A (5850 unit) + Zinc (15 mg) + alpha-Tocopherol acetate (45 unit)	Tablet	Oral	Garden State Nutritionals	Not applicable	Not applicable
Multivitamins and Minerals Tablets	Nickel sulfate (5 mcg) + Ascorbic acid (120 mg) + Beta carotene (1000 unit) + Biotin (40 mcg) + Calcium (162 mg) + Calcium Phosphate (125 mg) + Cholecalciferol (400 unit) + Chromic chloride (120 mcg) + Cupric sulfate (2 mg) + Cyanocobalamin (18 mcg) + Ferrous fumarate (15 mg) + Folic acid (0.4 mg) + Magnesium (50 mg) + Manganese (4 mg) + Nicotinamide (40 mg) + Calcium pantothenate (10 mg) + Potassium (80 mg) + Potassium Iodide (0.150 mg) + Potassium chloride (72 mg) + Pyridoxine hydrochloride (6 mg) + Riboflavin (5.1 mg) + Sodium selenite (70 mcg) + Silicon (4 mg) + Sodium metavanadate (10 mcg) + Sodium molybdate (50 mcg) + Stannous chloride (0.010 mg) + Thiamine mononitrate (4.5 mg) + Vitamin A (4000 unit) + Zinc (15 mg) + alpha-Tocopherol acetate (60 unit)	Tablet	Oral	Pharmetics (2011) Inc.	2004-06-03	2009-07-30
Spectrum Performa Multivitamins and Minerals Tablets	Nickel sulfate (5 mcg) + Ascorbic acid (120 mg) + Beta carotene (1000 unit) + Biotin (40 mcg) + Calcium (162 mg) + Calcium Phosphate (125 mg) + Cholecalciferol (400 unit) + Chromic chloride (120 mcg) + Cupric sulfate (2 mg) + Cyanocobalamin (18 mcg) + Ferrous fumarate (18 mg) + Folic acid (0.4 mg) + Magnesium (50 mg) + Manganese (4 mg) + Nicotinamide (40 mg) + Calcium pantothenate (10 mg) + Potassium (80 mg) + Potassium Iodide (0.15 mg) + Potassium chloride (72 mg) + Pyridoxine hydrochloride (6 mg) + Riboflavin (5.1 mg) + Sodium selenite (70 mcg) + Silicon (4 mg) + Sodium metavanadate (10 mcg) + Sodium molybdate (50 mcg) + Stannous chloride (0.01 mg) + Thiamine mononitrate (4.5 mg) + Vitamin A (4000 unit) + Zinc (15 mg) + alpha-Tocopherol acetate (60 unit)	Tablet	Oral	Pharmetics (2011) Inc.	2003-03-12	2009-07-30
T.R.U.E. Test Thin-Layer Rapid Use Patch Test	Nickel sulfate hexahydrate (36 ug/48h) + 2,2'-Dibenzothiazyl disulfide (20 ug/48h) + 2-mercaptobenzothiazole (61 ug/48h) + 4-(Isopropylamino)diphenylamine (10 ug/48h) + Bacitracin (486 ug/48h) + Balsam of Peru (648 ug/48h) + Benzocaine (378 ug/48h) + Benzylparaben (162 ug/48h) + Bisphenol A diglycidyl ether (32 ug/48h) + Bromothalonil (4 ug/48h) + Bronopol (203 ug/48h) + Budesonide (0.8 ug/48h) + Butylparaben (162 ug/48h) + Chlorquinaldol (77 ug/48h) + Cinchocaine hydrochloride (66 ug/48h) + Cinnamaldehyde (41 ug/48h) + Cinnamyl alcohol (63 ug/48h) + Clioquinol (77 ug/48h) + Cobalt chloride hexahydrate (4 ug/48h) + Diazolidinylurea (446 ug/48h) + Potassium dichromate (15.7 ug/48h) + Dipentamethylenethiuram disulfide (5.5 ug/48h) + Diphenylguanidine (68 ug/48h) + Disperse Blue 106 (41 ug/48h) + Disulfiram (5.5 ug/48h) + Ditiocarb zinc (68 ug/48h) + Ethyl hydroxybenzoate (162 ug/48h) + Ethylenediamine (18 ug/48h) + Eugenol (41 ug/48h) + Evernia prunastri (81 ug/48h) + Formaldehyde (146 ug/48h) + Geraniol (81 ug/48h) + Hydrocortisone butyrate (16 ug/48h) + Hydroxycitronellal (63 ug/48h) + Imidurea (486 ug/48h) + Isoeugenol (17 ug/48h) + Lanolin alcohols (810 ug/48h) + Methylchloroisothiazolinone (3 ug/48h) + Methylparaben (162 ug/48h) + Morpholinylmercaptobenzothiazole (20 ug/48h) + N,N'-diphenyl-1,4-phenylenediamine (25 ug/48h) + N-Cyclohexyl-N'-phenyl-1,4-phenylenediamine (25 ug/48h) + Neomycin sulfate (486 ug/48h) + Parthenolide (2 ug/48h) + Propylparaben (162 ug/48h) + Quaternium-15 (81 ug/48h) + Rosin (972 ug/48h) + Sodium aurotiosulfate (23 ug/48h) + Tetracaine hydrochloride (66 ug/48h) + Tetramethylthiuram monosulfide (5.5 ug/48h) + Thimerosal (6 ug/48h) + Thiohexam (20 ug/48h) + Thiram (5.5 ug/48h) + Tixocortol pivalate (2 ug/48h) + Zinc dibutyldithiocarbamate (68 ug/48h) + alpha-Amyl cinnamaldehyde (17 ug/48h) + p-Phenylenediamine (65 ug/48h) + p-tert-Butylphenol-formaldehyde resin (low molecular weight) (36 ug/48h)	Kit	Cutaneous	SmartPractice Denmark ApS	2012-03-01	Not applicable

Chemical Identifiers

UNII: 4FLT4T3WUN
CAS number: 7786-81-4
InChI Key: LGQLOGILCSXPEA-UHFFFAOYSA-L
InChI: InChI=1S/Ni.H2O4S/c;1-5(2,3)4/h;(H2,1,2,3,4)/q+2;/p-2
IUPAC Name: nickel(2+) sulfate
SMILES: [Ni++].[O-]S([O-])(=O)=O

References

General References

Not Available

External Links

ChemSpider: 22989
RxNav: 31738
ChEBI: 53001
ChEMBL: CHEMBL3990696
Wikipedia: Nickel(II)_sulfate

Clinical Trials

Clinical Trials

Phase	Status	Purpose	Conditions	Count

Pharmacoeconomics

Manufacturers

Not Available

Packagers

Not Available

Dosage Forms

Form	Route	Strength
Tablet	Oral
Kit	Cutaneous

Prices

Not Available

Patents

Not Available

Properties

State

Not Available

Experimental Properties

Not Available

Predicted Properties

Property	Value	Source
logP	-0.84	Chemaxon
pKa (Strongest Acidic)	-3	Chemaxon
Physiological Charge	-2	Chemaxon
Hydrogen Acceptor Count	4	Chemaxon
Hydrogen Donor Count	0	Chemaxon
Polar Surface Area	80.26 Å²	Chemaxon
Rotatable Bond Count	0	Chemaxon
Refractivity	11.53 m³·mol^-1	Chemaxon
Polarizability	5.81 Å³	Chemaxon
Number of Rings	0	Chemaxon
Bioavailability	1	Chemaxon
Rule of Five	Yes	Chemaxon
Ghose Filter	No	Chemaxon
Veber's Rule	No	Chemaxon
MDDR-like Rule	No	Chemaxon

Predicted ADMET Features

Not Available

Spectra

Mass Spec (NIST): Not Available
Spectra: Not Available
Chromatographic Properties: Collision Cross Sections (CCS)
Not Available

Drug created at July 03, 2018 15:18 / Updated at September 28, 2021 21:54

Nickel sulfate

Identification

Structure for Nickel sulfate (DB14180)

Pharmacology

Interactions

Products

Categories

Chemical Identifiers

References

Clinical Trials

Pharmacoeconomics

Properties

Spectra

Collision Cross Sections (CCS)