Influenza A virus A/South Dakota/6/2007 (H1N1) live (attenuated) antigen

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Identification

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Name
Influenza A virus A/South Dakota/6/2007 (H1N1) live (attenuated) antigen
Accession Number
DB14446
Type
Biotech
Groups
Approved
Biologic Classification
Vaccines
Attenuated
Description

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence against future exposure to the virus, or "antigen". This defence includes the production of humoral immunity through the development of antibodies (through memory B cells) and of cell-mediated immunity through the production of T-lymphocytes. Upon re-exposure to infectious influenza virus, the immune system is prepared to identify and destroy the virus as there are circulating antibodies that recognize that particular component of the virus that it was previously exposed to.

There are two basic types of vaccines available: inactivated influenza vaccine (IIV) and live attenuated influenza vaccine (LAIV). Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed, or inactivated, through exposure to heat or chemicals such as formaldehyde 3. Inactivated virus cannot replicate, and therefore cannot cause disease from infection, even in immunocompromised individuals. In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated, or weakened, through various laboratory techniques. Live vaccines maintain their replicative ability.

Synonyms
  • Influenza a Virus A/south Dakota/6/2007 (H1n1) Live(attenuated) Antigen
  • Influenza a Virus A/south Dakota/6/2007(h1n1) Live(attenuated) Antigen
  • Influenza a Virus H1n1 Live Antigen, A
Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing End
FluMistInfluenza A virus A/South Dakota/6/2007 (H1N1) live (attenuated) antigen (10000000 1/0.2mL) + Influenza A virus A/Uruguay/716/2007(H3N2) live (attenuated) antigen (10000000 1/0.2mL) + Influenza B virus B/Brisbane/60/2008 live (attenuated) antigen (10000000 1/0.2mL)SprayNasalMed Immune, Llc2009-07-172010-04-19Us
Categories
Not Available
UNII
5POT1F3XH8
CAS number
Not Available

Pharmacology

Indication
Not Available
Pharmacodynamics
Not Available
Mechanism of action
Not Available
Absorption
Not Available
Volume of distribution
Not Available
Protein binding
Not Available
Metabolism
Not Available
Route of elimination
Not Available
Half life
Not Available
Clearance
Not Available
Toxicity
Not Available
Affected organisms
Not Available
Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

References

General References
Not Available
External Links
Not Available

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
1CompletedNot AvailableFlu caused by Influenza / Healthy Volunteers1
1CompletedNot AvailableMalignancies1
1CompletedBasic ScienceHealthy Volunteers1
1CompletedBasic ScienceInfluenza, Human1
1CompletedPreventionFlu caused by Influenza1
1CompletedPreventionHealthy Volunteers1
1CompletedPreventionMalignancies1
1, 2CompletedPreventionEgg Allergy / Eligible for Vaccination Against Influenza1
1, 2CompletedPreventionFlu caused by Influenza / Human Immunodeficiency Virus (HIV) Infections1
1, 2TerminatedPreventionInfluenza, Human1
2CompletedPreventionFlu caused by Influenza1
2CompletedPreventionHealthy Volunteers1
2CompletedTreatmentHealthy Volunteers2
2CompletedTreatmentInfluenza Vaccines1
2, 3CompletedPreventionHealthy or Stable Underlying Chronic Medical Condition1
3CompletedNot AvailableFlu caused by Influenza / Healthy Volunteers1
3CompletedPreventionFlu caused by Influenza3
3CompletedPreventionHealthy or Stable Chronic Illness1
3CompletedPreventionHealthy or Stable Underlying Chronic Medical Condition1
3CompletedTreatmentHealthy Volunteers2
4CompletedNot AvailableFlu caused by Influenza1
4CompletedNot AvailableHealthy Volunteers1
4CompletedBasic ScienceFlu caused by Influenza8
4CompletedBasic ScienceFlu caused by Influenza / Healthy Volunteers2
4CompletedBasic ScienceImmune Response to Influenza Vaccine / Influenza A Virus Infection / Influenza B Virus Infection1
4CompletedHealth Services ResearchInfluenza, Human / Pneumonia1
4CompletedPreventionAsthma1
4CompletedPreventionFlu caused by Influenza7
4CompletedPreventionFlu caused by Influenza / Healthy Volunteers1
4CompletedPreventionInfluenza Vaccines Efficacy and Safety1
4CompletedPreventionInfluenza Virus Infection / Influenza-like illness or flu-like symptoms / Respiratory Infections, Acute1
4CompletedTreatmentFlu caused by Influenza2
4CompletedTreatmentHealthy Volunteers1
4Not Yet RecruitingBasic ScienceFlu caused by Influenza2
4RecruitingPreventionImmune Response / Influenza, Human1
4TerminatedBasic ScienceFlu caused by Influenza2
4TerminatedPreventionFlu caused by Influenza1
4Unknown StatusBasic ScienceFlu caused by Influenza1
Not AvailableCompletedNot AvailableCentral Nervous System Neoplasms1
Not AvailableCompletedNot AvailableEgg Hypersensitivity1
Not AvailableCompletedNot AvailableFlu caused by Influenza / H1N1 / Human Immunodeficiency Virus Type 1 (HIV-1) Infection1
Not AvailableCompletedNot AvailableHealthy Volunteers2
Not AvailableCompletedBasic ScienceFlu caused by Influenza1
Not AvailableCompletedHealth Services ResearchImmune Response to Influenza Vaccination1
Not AvailableCompletedTreatmentFlu caused by Influenza1
Not AvailableEnrolling by InvitationPreventionTonsillitis, Hypertrophy1
Not AvailableRecruitingNot AvailableHabits / Influenza, Human / Respiratory Tract Infections (RTI) / Smoking1
Not AvailableRecruitingBasic ScienceHealthy Volunteers1
Not AvailableTerminatedBasic ScienceFlu caused by Influenza1
Not AvailableUnknown StatusNot AvailableCystic Fibrosis (CF)1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage forms
FormRouteStrength
SprayNasal
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available

Taxonomy

Classification
Not classified

Drug created on July 05, 2018 12:03 / Updated on December 02, 2019 10:12