Influenza B virus B/Brisbane/9/2014 antigen (formaldehyde inactivated)

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

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Name
Influenza B virus B/Brisbane/9/2014 antigen (formaldehyde inactivated)
Accession Number
DB14456
Type
Biotech
Groups
Approved
Biologic Classification
Vaccines
Inactivated
Description

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence against future exposure to the virus, or "antigen". This defence includes the production of humoral immunity through the development of antibodies (through memory B cells) and of cell-mediated immunity through the production of T-lymphocytes. Upon re-exposure to infectious influenza virus, the immune system is prepared to identify and destroy the virus as there are circulating antibodies that recognize that particular component of the virus that it was previously exposed to.

There are two basic types of vaccines available: inactivated influenza vaccine (IIV) and live attenuated influenza vaccine (LAIV). Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed, or inactivated, through exposure to heat or chemicals such as formaldehyde 3. Inactivated virus cannot replicate, and therefore cannot cause disease from infection, even in immunocompromised individuals. In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated, or weakened, through various laboratory techniques. Live vaccines maintain their replicative ability.

Synonyms
Not Available
Active Moieties
NameKindUNIICASInChI Key
Influenza B virus B/Brisbane/9/2014 hemagglutinin antigen (formaldehyde inactivated)hemagglutininJLT4EPW55ANot AvailableNot applicable
Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing End
FluadInfluenza B virus B/Brisbane/9/2014 antigen (formaldehyde inactivated) (15 ug/0.5mL) + Influenza A virus A/California/7/2009 X-181 (H1N1) antigen (formaldehyde inactivated) (15 ug/0.5mL) + Influenza A virus A/Switzerland/9715293/2013 NIB-88 (H3N2) antigen (formaldehyde inactivated) (15 ug/0.5mL)Injection, suspensionIntramuscularNovartis Vaccines And Diagnostics, Inc.2015-11-242018-07-02Us
Categories
Not Available
UNII
NA2830I822
CAS number
Not Available

Pharmacology

Indication
Not Available
Pharmacodynamics
Not Available
Mechanism of action
Not Available
Absorption
Not Available
Volume of distribution
Not Available
Protein binding
Not Available
Metabolism
Not Available
Route of elimination
Not Available
Half life
Not Available
Clearance
Not Available
Toxicity
Not Available
Affected organisms
Not Available
Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

References

General References
Not Available
External Links
Not Available

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
2Active Not RecruitingPreventionFlu caused by Influenza1
2CompletedOtherFlu caused by Influenza1
2CompletedPreventionFlu caused by Influenza1
2CompletedPreventionImmunocompromised / Transplanted1
2CompletedPreventionProphylaxis of Avian Influenza Vaccine1
3CompletedPreventionChronic Heart Disease / Chronic Pulmonary Disease / Diabetes Mellitus / H1N1 Influenza Virus1
3CompletedPreventionFlu caused by Influenza1
3CompletedPreventionInfluenza Disease1
3CompletedPreventionInfluenza, Human1
4Active Not RecruitingBasic ScienceFlu caused by Influenza / Healthy Adults / Hepatitis A / Salmonella Typhi Infection1
4Active Not RecruitingBasic ScienceFlu caused by Influenza / Vaccine Response to Either FluadĀ® (MF59Flu) or FluzoneĀ® (HDFlu)1
4Active Not RecruitingBasic ScienceSafety Markers of Adjuvanted Influenza Vaccine1
4Active Not RecruitingPreventionFlu caused by Influenza / Influenza-like illness or flu-like symptoms1
4CompletedPreventionAdverse Drug Events / Injection Site Reactions / Pain / Quality of Life / Side Effect of Drug1
4CompletedPreventionChronic Kidney Disease (CKD) / Chronic Renal Failure (CRF) / Flu caused by Influenza1
4CompletedPreventionFlu caused by Influenza1
4CompletedPreventionFlu caused by Influenza / Streptococcus Pneumoniae1
4CompletedPreventionInfections, Pneumococcal / Influenza, Human1
4CompletedPreventionInfluenza Vaccines1
4Not Yet RecruitingBasic ScienceFlu caused by Influenza1
4Not Yet RecruitingPreventionInfluenza Vaccines / Transplantations1
4RecruitingNot AvailableFlu caused by Influenza1
4RecruitingTreatmentFlu caused by Influenza1
Not AvailableCompletedBasic ScienceHealthy Volunteers2
Not AvailableCompletedBasic ScienceImmune Response1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage forms
FormRouteStrength
Injection, suspensionIntramuscular
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available

Taxonomy

Classification
Not classified

Drug created on July 05, 2018 12:03 / Updated on February 02, 2020 03:12