Sodium ascorbate
Identification
- Name
- Sodium ascorbate
- Accession Number
- DB14482 (DBSALT001764)
- Type
- Small Molecule
- Groups
- Approved, Nutraceutical
- Description
- Not Available
- Structure
- Synonyms
- Ascorbato sódico
- Ascorbic acid sodium salt
- L-Ascorbic acid sodium salt
- L-Ascorbic acid, monosodium salt
- Monosodium L-ascorbate
- Sodium ascorbate
- sodium L-ascorbate
- Vitamin C sodium
- Vitamin C, sodium salt
- Active Moieties
Name Kind UNII CAS InChI Key Ascorbic acid unknown PQ6CK8PD0R 50-81-7 CIWBSHSKHKDKBQ-JLAZNSOCSA-N Sodium cation ionic LYR4M0NH37 17341-25-2 FKNQFGJONOIPTF-UHFFFAOYSA-N - Prescription Products
Name Dosage Strength Route Labeller Marketing Start Marketing End Unlock Additional DataMega-C-sodium Inj 250mg/ml Solution Intravenous Kripps Pharmacy Ltd. 1981-12-31 Not applicable Canada Vitamin C Liquid 250 mg Intramuscular; Intravenous Sandoz Canada Incorporated 1989-12-31 Not applicable Canada Additional Data Available- Application NumberApplication Number
A unique ID assigned by the FDA when a product is submitted for approval by the labeller.
Learn more - Product CodeProduct Code
A governmentally-recognized ID which uniquely identifies the product within its regulatory market.
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- Over the Counter Products
Name Dosage Strength Route Labeller Marketing Start Marketing End Unlock Additional DataC Wafer 500 Chewable 500mg Wafer Oral Nu Life Nutrition Ltd. 1986-12-31 2000-05-23 Canada Natural Fruit Chew C 250mg Tangy Orange Flavour Tablet Oral Natural Factors Nutritional Products Ltd. 2001-01-01 2009-09-28 Canada Sodium Ascor Crystal 888.8mg/gm USP Powder Oral Vita Health Products Inc 1996-10-11 2002-07-31 Canada Tgi Tab 50mg Tablet Oral Seroyal International Inc. 1980-12-31 1996-09-10 Canada Vitamin C 60mg Tablet Oral Wn Pharmaceuticals Ltd. 1999-04-09 2008-07-17 Canada Additional Data Available- Application NumberApplication Number
A unique ID assigned by the FDA when a product is submitted for approval by the labeller.
Learn more - Product CodeProduct Code
A governmentally-recognized ID which uniquely identifies the product within its regulatory market.
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- Mixture Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Animal Shaped Chew Vit C Tab 250mg Sodium ascorbate (159 mg) + Ascorbic acid (110 mg) Tablet Oral Hall Laboratories, Ltd. 1982-12-31 2003-09-11 Canada Appedrine Sodium ascorbate (10 mg) + Benzocaine (3 mg) + Ferrous fumarate (3.33 mg) + Nicotinamide (3.33 mg) + Riboflavin (.4 mg) + Thiamine hydrochloride (.33 mg) + Vitamin A (1333 unit) + Vitamin D (133 unit) Tablet Oral Chattem, Inc. 1975-12-31 2004-07-08 Canada Ascorbex 500 Tab Sodium ascorbate (337.5 mg) + Ascorbic acid (200 mg) Tablet Oral SantÉ Naturelle (Ag) LtÉe 1988-12-31 2004-08-05 Canada Bugs Bunny and Friends Multiple Vitamins Sodium ascorbate (50 mg) + Cyanocobalamin (3 mcg) + Folic acid (0.1 mg) + Nicotinamide (15 mg) + Pyridoxine hydrochloride (1 mg) + Riboflavin (1.5 mg) + Thiamine mononitrate (1.5 mg) + Vitamin A (5000 unit) + Vitamin D (400 unit) Tablet Oral Bayer Inc Consumer Care 1996-12-31 2004-04-15 Canada Bugs Bunny Chew Multi Vit Plus Iron Sodium ascorbate (50 mg) + Cyanocobalamin (3 mcg) + Ferrous fumarate (12 mg) + Folic acid (.1 mg) + Nicotinamide (15 mg) + Pyridoxine hydrochloride (1 mg) + Riboflavin (1.5 mg) + Thiamine mononitrate (1.5 mg) + Vitamin A acetate (5000 unit) + Vitamin D (400 unit) Tablet Oral Miles Inc. Pharmaceutical Division 1983-12-31 1996-09-09 Canada Chewable Multiple Vitamins for Children Sodium ascorbate (50 mg) + Cyanocobalamin (3 mcg) + Folic acid (.1 mg) + Nicotinamide (15 mg) + Pyridoxine hydrochloride (1 mg) + Riboflavin (1.5 mg) + Thiamine mononitrate (1.5 mg) + Vitamin A acetate (5000 unit) + Vitamin D (400 unit) Tablet Oral Randle Pharmaceutical Inc. 1996-09-19 1999-09-03 Canada Chewable Multivitamins Sodium ascorbate (50 mg) + Cholecalciferol (400 unit) + Cyanocobalamin (3 mcg) + Folic acid (0.1 mg) + Nicotinamide (15 mg) + Pyridoxine hydrochloride (1 mg) + Riboflavin (1.5 mg) + Thiamine mononitrate (1.5 mg) + Vitamin A (5000 unit) Tablet Oral Wn Pharmaceuticals Ltd. 2002-05-31 2008-07-17 Canada Chewable Multivitamins Plus Iron Sodium ascorbate (50 mg) + Cholecalciferol (400 unit) + Cyanocobalamin (3 mcg) + Ferrous fumarate (4 mg) + Folic acid (0.1 mg) + Nicotinamide (15 mg) + Pyridoxine hydrochloride (1 mg) + Riboflavin (1.5 mg) + Thiamine mononitrate (1.5 mg) + Vitamin A (5000 unit) Tablet Oral Wn Pharmaceuticals Ltd. 2002-05-31 2007-08-07 Canada Chewable Vit C 100mg Sodium ascorbate (50 mg) + Ascorbic acid (50 mg) Tablet Oral Bioforce Canada Inc. 1994-12-31 1997-04-04 Canada Chewable Vitamin C 100mg - Tab Sodium ascorbate (79 mg) + Ascorbic acid (30 mg) Tablet Oral Vita Health Products Inc 1996-10-18 2002-07-31 Canada - Unapproved/Other Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Centratex Sodium ascorbate (200 mg/1) + Cupric sulfate (0.8 mg/1) + Cyanocobalamin (15 ug/1) + Folic acid (1 mg/1) + Iron (106 mg/1) + Magnesium sulfate (6.9 mg/1) + Manganese sulfate (1.3 mg/1) + Nicotinamide (30 mg/1) + Calcium pantothenate (10 mg/1) + Pyridoxine hydrochloride (5 mg/1) + Riboflavin (6 mg/1) + Thiamine mononitrate (10 mg/1) + Zinc sulfate, unspecified form (18.2 mg/1) Capsule Oral Centurion Labs 2009-06-14 Not applicable US Irospan 24/6 Sodium ascorbate (100 mg/1) + Sodium ascorbate (100 mg/1) + Biotin (300 ug/1) + Biotin (300 ug/1) + Calcium carbonate (100 mg/1) + Cyanocobalamin (10 ug/1) + Cyanocobalamin (10 ug/1) + Ferrous bisglycinate (65 mg/1) + Folic acid (1 mg/1) + Folic acid (1 mg/1) + Calcium formate (155 mg/1) + Iron Dextran (65 mg/1) + Niacin (25 mg/1) + Niacin (25 mg/1) + Calcium pantothenate (300 ug/1) + Calcium pantothenate (7 mg/1) + Pyridoxine hydrochloride (30 mg/1) + Pyridoxine hydrochloride (30 mg/1) + Riboflavin sodium (5 mg/1) + Riboflavin (5 mg/1) + Succinic acid (150 mg/1) + Thiamine hydrochloride (5 mg/1) + Thiamine hydrochloride (5 mg/1) Oral WOMENS CHOICE PHARMACEUTICALS LLC 2011-04-15 Not applicable US Irospan 24/6 Sodium ascorbate (100 mg/1) + Sodium ascorbate (100 mg/1) + Biotin (300 ug/1) + Biotin (300 ug/1) + Calcium carbonate (100 mg/1) + Cyanocobalamin (10 ug/1) + Cyanocobalamin (10 ug/1) + Ferrous bisglycinate (65 mg/1) + Folic acid (1 mg/1) + Folic acid (1 mg/1) + Calcium formate (155 mg/1) + Iron Dextran (65 mg/1) + Niacin (25 mg/1) + Niacin (25 mg/1) + Calcium pantothenate (300 ug/1) + Calcium pantothenate (7 mg/1) + Pyridoxine hydrochloride (30 mg/1) + Pyridoxine hydrochloride (30 mg/1) + Riboflavin sodium (5 mg/1) + Riboflavin (5 mg/1) + Succinic acid (150 mg/1) + Thiamine hydrochloride (5 mg/1) + Thiamine hydrochloride (5 mg/1) Oral WOMENS CHOICE PHARMACEUTICALS LLC 2011-04-15 Not applicable US Multi Vitamin with Fluoride Sodium ascorbate (36 mg/1) + Ascorbic acid (24 mg/1) + Cholecalciferol (400 [iU]/1) + Cyanocobalamin (4.5 ug/1) + DL-alpha tocopheryl acetate (15 [iU]/1) + Folic acid (0.3 mg/1) + Nicotinamide (13.5 mg/1) + Pyridoxine hydrochloride (1.05 mg/1) + Riboflavin (1.2 mg/1) + Sodium fluoride (1 mg/1) + Thiamine mononitrate (1.05 mg/1) + Vitamin A acetate (2500 [iU]/1) Tablet, chewable Oral Qualitest 2009-10-09 2014-12-31 US Multi Vitamin with Fluoride Sodium ascorbate (36 mg/1) + Ascorbic acid (24 mg/1) + Cholecalciferol (400 [iU]/1) + Cyanocobalamin (4.5 ug/1) + DL-alpha tocopheryl acetate (15 [iU]/1) + Folic acid (0.3 mg/1) + Nicotinamide (13.5 mg/1) + Pyridoxine hydrochloride (1.05 mg/1) + Riboflavin (1.2 mg/1) + Sodium fluoride (0.5 mg/1) + Thiamine mononitrate (1.05 mg/1) + Vitamin A acetate (2500 [iU]/1) Tablet, chewable Oral A S Medication Solutions 2009-10-09 Not applicable US Multi Vitamin with Fluoride Sodium ascorbate (36 mg/1) + Ascorbic acid (24 mg/1) + Cholecalciferol (400 [iU]/1) + Cyanocobalamin (4.5 ug/1) + DL-alpha tocopheryl acetate (15 [iU]/1) + Folic acid (0.3 mg/1) + Nicotinamide (13.5 mg/1) + Pyridoxine hydrochloride (1.05 mg/1) + Riboflavin (1.2 mg/1) + Sodium fluoride (0.5 mg/1) + Thiamine mononitrate (1.05 mg/1) + Vitamin A acetate (2500 [iU]/1) Tablet, chewable Oral Qualitest 2009-10-09 2014-12-31 US Multi Vitamin with Fluoride Sodium ascorbate (36 mg/1) + Ascorbic acid (24 mg/1) + Cholecalciferol (400 [iU]/1) + Cyanocobalamin (4.5 ug/1) + DL-alpha tocopheryl acetate (15 [iU]/1) + Folic acid (0.3 mg/1) + Nicotinamide (13.5 mg/1) + Pyridoxine hydrochloride (1.05 mg/1) + Riboflavin (1.2 mg/1) + Sodium fluoride (1 mg/1) + Thiamine mononitrate (1.05 mg/1) + Vitamin A acetate (2500 [iU]/1) Tablet, chewable Oral Physicians Total Care, Inc. 2003-06-04 2013-01-15 US Multi Vitamin with Fluoride Sodium ascorbate (36 mg/1) + Ascorbic acid (24 mg/1) + Cholecalciferol (400 [iU]/1) + Cyanocobalamin (4.5 ug/1) + DL-alpha tocopheryl acetate (15 [iU]/1) + Folic acid (0.3 mg/1) + Nicotinamide (13.5 mg/1) + Pyridoxine hydrochloride (1.05 mg/1) + Riboflavin (1.2 mg/1) + Sodium fluoride (0.25 mg/1) + Thiamine mononitrate (1.05 mg/1) + Vitamin A acetate (2500 [iU]/1) Tablet, chewable Oral Qualitest 2009-10-09 2014-08-31 US Multi Vitamin with Fluoride Sodium ascorbate (36 mg/1) + Ascorbic acid (24 mg/1) + Cholecalciferol (400 [iU]/1) + Cyanocobalamin (4.5 ug/1) + DL-alpha tocopheryl acetate (15 [iU]/1) + Folic acid (0.3 mg/1) + Nicotinamide (13.5 mg/1) + Pyridoxine hydrochloride (1.05 mg/1) + Riboflavin (1.2 mg/1) + Sodium fluoride (0.5 mg/1) + Thiamine mononitrate (1.05 mg/1) + Vitamin A acetate (2500 [iU]/1) Tablet, chewable Oral Physicians Total Care, Inc. 2003-09-08 2013-01-15 US Multi Vitamin with Fluoride Sodium ascorbate (36 mg/1) + Ascorbic acid (24 mg/1) + Cholecalciferol (400 [iU]/1) + Cyanocobalamin (4.5 ug/1) + DL-alpha tocopheryl acetate (15 [iU]/1) + Folic acid (0.3 mg/1) + Nicotinamide (13.5 mg/1) + Pyridoxine hydrochloride (1.05 mg/1) + Riboflavin (1.2 mg/1) + Sodium fluoride (0.25 mg/1) + Thiamine mononitrate (1.05 mg/1) + Vitamin A acetate (2500 [iU]/1) Tablet, chewable Oral Physicians Total Care, Inc. 2003-09-05 2013-01-15 US - Categories
- UNII
- S033EH8359
- CAS number
- 134-03-2
- Weight
- Average: 198.106
Monoisotopic: 198.01403223 - Chemical Formula
- C6H7NaO6
- InChI Key
- PPASLZSBLFJQEF-RXSVEWSESA-M
- InChI
- InChI=1S/C6H8O6.Na/c7-1-2(8)5-3(9)4(10)6(11)12-5;/h2,5,7-10H,1H2;/q;+1/p-1/t2-,5+;/m0./s1
- IUPAC Name
- sodium (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate
- SMILES
- [Na+].[H][C@@]1(OC(=O)C(O)=C1[O-])[C@@H](O)CO
Pharmacology
- Indication
- Not Available
- Associated Therapies
- Pharmacodynamics
- Not Available
- Mechanism of action
- Not Available
- Absorption
- Not Available
- Volume of distribution
- Not Available
- Protein binding
- Not Available
- Metabolism
- Not Available
- Route of elimination
- Not Available
- Half life
- Not Available
- Clearance
- Not Available
- Toxicity
- Not Available
- Affected organisms
- Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Comprehensive structured data on known drug adverse effects with statistical prevalence. MedDRA and ICD10 ids are provided for adverse effect conditions and symptoms.
Learn moreStructured data covering drug contraindications. Each contraindication describes a scenario in which the drug is not to be used. Includes restrictions on co-administration, contraindicated populations, and more.
Learn moreStructured data representing warnings from the black box section of drug labels. These warnings cover important and dangerous risks, contraindications, or adverse effects.
Learn moreInteractions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Drug Interaction Unlock Additional Data2,5-Dimethoxy-4-ethylamphetamine The serum concentration of 2,5-Dimethoxy-4-ethylamphetamine can be decreased when it is combined with Sodium ascorbate. 2,5-Dimethoxy-4-ethylthioamphetamine The serum concentration of 2,5-Dimethoxy-4-ethylthioamphetamine can be decreased when it is combined with Sodium ascorbate. 4-Bromo-2,5-dimethoxyamphetamine The serum concentration of 4-Bromo-2,5-dimethoxyamphetamine can be decreased when it is combined with Sodium ascorbate. Acetazolamide The risk or severity of adverse effects can be increased when Acetazolamide is combined with Sodium ascorbate. Aclidinium The therapeutic efficacy of Sodium ascorbate can be decreased when used in combination with Aclidinium. Agmatine The therapeutic efficacy of Sodium ascorbate can be decreased when used in combination with Agmatine. Alcuronium The therapeutic efficacy of Sodium ascorbate can be decreased when used in combination with Alcuronium. Alfentanil The therapeutic efficacy of Sodium ascorbate can be decreased when used in combination with Alfentanil. Alloin The risk or severity of adverse effects can be increased when Sodium ascorbate is combined with Alloin. Almasilate The therapeutic efficacy of Sodium ascorbate can be decreased when used in combination with Almasilate. Additional Data Available- Extended DescriptionExtended Description
Extended description of the mechanism of action and particular properties of each drug interaction.
Learn more - Severity
- Evidence Level
- ActionAction
An effect category for each drug interaction. Know how this interaction affects the subject drug.
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- Food Interactions
- Not Available
References
- General References
- Not Available
- External Links
- KEGG Drug
- D05853
- ChemSpider
- 16736174
- ChEBI
- 113451
- ChEMBL
- CHEMBL591665
- PharmGKB
- PA166163262
- Wikipedia
- Sodium_ascorbate
- AHFS Codes
- 88:12.00 — Vitamin C
Clinical Trials
- Clinical Trials
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage forms
Form Route Strength Wafer Oral Solution Intravenous Kit Oral Powder, for solution Oral Tablet, chewable Oral Tablet Oral Tablet, film coated Oral Kit Intravenous Tablet Oral Liquid Oral Powder Oral Capsule, gelatin coated Oral Powder Oral Capsule Oral Tablet, coated Oral Liquid Intramuscular; Intravenous 250 mg Lozenge Oral - Prices
- Not Available
- Patents
Patent Number Pediatric Extension Approved Expires (estimated) Unlock Additional DataUS7169381 No 2007-01-30 2024-09-01 US US7658914 No 2010-02-09 2024-09-01 US US9326969 No 2016-05-03 2033-09-10 US US9592252 No 2017-03-14 2032-08-11 US US9707297 No 2017-07-18 2033-09-10 US US8999313 No 2015-04-07 2033-09-10 US US10016504 No 2018-07-10 2033-09-10 US Additional Data Available- Filed On
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 625.0 mg/mL ALOGPS logP -1.4 ALOGPS logP -1.9 ChemAxon logS 0.5 ALOGPS pKa (Strongest Acidic) 4.36 ChemAxon pKa (Strongest Basic) -3 ChemAxon Physiological Charge -1 ChemAxon Hydrogen Acceptor Count 5 ChemAxon Hydrogen Donor Count 3 ChemAxon Polar Surface Area 110.05 Å2 ChemAxon Rotatable Bond Count 2 ChemAxon Refractivity 47.58 m3·mol-1 ChemAxon Polarizability 14.51 Å3 ChemAxon Number of Rings 1 ChemAxon Bioavailability 1 ChemAxon Rule of Five Yes ChemAxon Ghose Filter No ChemAxon Veber's Rule No ChemAxon MDDR-like Rule No ChemAxon - Predicted ADMET features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Not Available
Taxonomy
- Description
- This compound belongs to the class of organic compounds known as butenolides. These are dihydrofurans with a carbonyl group at the C2 carbon atom.
- Kingdom
- Organic compounds
- Super Class
- Organoheterocyclic compounds
- Class
- Dihydrofurans
- Sub Class
- Furanones
- Direct Parent
- Butenolides
- Alternative Parents
- Vinylogous acids / Enoate esters / Secondary alcohols / Lactones / 1,2-diols / Oxacyclic compounds / Monocarboxylic acids and derivatives / Primary alcohols / Organic zwitterions / Organic sodium salts show 3 more
- Substituents
- 2-furanone / Enoate ester / Alpha,beta-unsaturated carboxylic ester / Vinylogous acid / 1,2-diol / Carboxylic acid ester / Lactone / Secondary alcohol / Monocarboxylic acid or derivatives / Carboxylic acid derivative show 13 more
- Molecular Framework
- Aliphatic heteromonocyclic compounds
- External Descriptors
- Not Available
Drug created on July 06, 2018 16:02 / Updated on December 09, 2019 19:34