Phosphate ion

Identification

Generic Name

Phosphate ion

DrugBank Accession Number

DB14523

Background

Not Available

Type

Small Molecule

Groups

Experimental

Structure

3D

Download

MOLSDF3D-SDFPDBSMILESInChI

Similar Structures

Structure for Phosphate ion (DB14523)

×

Close

Weight

Average: 94.9714
Monoisotopic: 94.95342

Chemical Formula

O₄P

Synonyms

• Orthophosphate
• Phosphate

Poor quality drug data slowing you down?

Unlock 38% more drug discovery time and eliminate decision-making doubts with this one-stop guide to quality drug data.

Download eBook

Poor quality drug data slowing you down?

Download eBook

Pharmacology

Indication

Not Available

Reduce drug development failure rates

Build, train, & validate machine-learning models
with evidence-based and structured datasets.

See how

Build, train, & validate predictive machine-learning models with structured datasets.

See how

Contraindications & Blackbox Warnings

Prevent Adverse Drug Events Today

Tap into our Clinical API for life-saving information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.

Learn more

Avoid life-threatening adverse drug events with our Clinical API

Learn more

Pharmacodynamics

Not Available

Mechanism of action

Not Available

Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism

Not Available

Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects

Improve decision support & research outcomes

With structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!

See the data

Improve decision support & research outcomes with our structured adverse effects data.

See a data sample

Toxicity

Not Available

Pathways

Not Available

Pharmacogenomic Effects/ADRs

Not Available

Interactions

Drug Interactions

This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.

• Approved
• Vet approved
• Nutraceutical
• Illicit
• Withdrawn
• Investigational
• Experimental
• All Drugs

Drug	Interaction
Integrate drug-drug interactions in your software
Aluminum hydroxide	Aluminum hydroxide can cause a decrease in the absorption of Phosphate ion resulting in a reduced serum concentration and potentially a decrease in efficacy.
Ferric ammonium citrate	Ferric ammonium citrate can cause a decrease in the absorption of Phosphate ion resulting in a reduced serum concentration and potentially a decrease in efficacy.
Ferric carboxymaltose	Ferric carboxymaltose can cause a decrease in the absorption of Phosphate ion resulting in a reduced serum concentration and potentially a decrease in efficacy.
Ferric cation	Ferric cation can cause a decrease in the absorption of Phosphate ion resulting in a reduced serum concentration and potentially a decrease in efficacy.
Ferric maltol	Ferric maltol can cause a decrease in the absorption of Phosphate ion resulting in a reduced serum concentration and potentially a decrease in efficacy.

Food Interactions

Not Available

Products

Drug product information from 10+ global regions

Our datasets provide approved product information including:
dosage, form, labeller, route of administration, and marketing period.

Access now

Access drug product information from over 10 global regions.

Access now

Over the Counter Products

Name	Dosage	Strength	Route	Labeller	Marketing Start	Marketing End	Region	Image
Liquidguard	Liquid	2.5 g/100mL	Topical	Nano Care Deutschland AG	2020-03-30	Not applicable

Mixture Products

Name	Ingredients	Dosage	Route	Labeller	Marketing Start	Marketing End	Region	Image
NUTRIFLEX LIPID PLUS INFUZYONLUK EMULSIYON, 1250 ML	Phosphate ion (15 mmol) + Acetate (45 mmol) + Alanine (5.82 g) + Arginine (3.24 g) + Aspartic acid (1.8 g) + Calcium (4 mmol) + Calcium chloride dihydrate (0.588 g) + Chlorine (45 mmol) + D-glucose (150 g) + Glutamic acid (4.21 g) + Glycine (1.98 g) + Histidine (1.5 g) + Isoleucine (2.82 g) + Leucine (3.76 g) + Lysine (2.73 g) + Magnesium (4 mmol) + Magnesium acetate tetrahydrate (0.858 g) + Medium-chain triglycerides (25 g) + Methionine (2.35 g) + Phenylalanine (4.21 g) + Potassium (35 mmol) + Potassium acetate (3.434 g) + Proline (4.08 g) + Serine (3.6 g) + Sodium acetate trihydrate (0.277 g) + Sodium cation (50 mmol) + Sodium chloride (0.503 g) + Sodium hydroxide (0.976 g) + Sodium phosphate, monobasic, dihydrate (2.34 g) + Soybean oil (25 g) + Threonine (2.18 g) + Tryptophan (0.68 g) + Valine (3.12 g) + Zinc (0.03 mmol) + Zinc acetate dihydrate (6.58 mg)	Injection, emulsion	Intravenous	B.BRAUN MEDİKAL DIŞ TİC. A.Ş.	2005-11-16	2018-10-03
NUTRIFLEX LIPID PLUS INFUZYONLUK EMULSIYON, 1870 ML	Phosphate ion (22.5 mmol) + Acetate (67.5 mmol) + Alanine (8.73 g) + Arginine (4.86 g) + Aspartic acid (2.7 g) + Calcium (6 mmol) + Calcium chloride dihydrate (0.882 g) + Chlorine (67.5 mmol) + D-glucose (225 g) + Glutamic acid (6.32 g) + Glycine (2.97 g) + Histidine (2.25 g) + Isoleucine (4.23 g) + Leucine (5.64 g) + Lysine (4.1 g) + Magnesium (6 mmol) + Magnesium acetate tetrahydrate (1.287 g) + Medium-chain triglycerides (37.5 g) + Methionine (3.53 g) + Phenylalanine (6.32 g) + Potassium (52.5 mmol) + Potassium acetate (5.151 g) + Proline (6.12 g) + Serine (5.4 g) + Sodium acetate trihydrate (0.416 g) + Sodium cation (75 mmol) + Sodium chloride (0.755 g) + Sodium hydroxide (1.464 g) + Sodium phosphate, monobasic, dihydrate (3.51 g) + Soybean oil (37.5 g) + Threonine (3.27 g) + Tryptophan (1.02 g) + Valine (4.68 g) + Zinc (0.045 mmol) + Zinc acetate dihydrate (9.87 mg)	Injection, emulsion	Intravenous	B.BRAUN MEDİKAL DIŞ TİC. A.Ş.	2005-11-16	2018-10-03
NUTRIFLEX LIPID PLUS INFUZYONLUK EMULSIYON, 2500 ML	Phosphate ion (30 mmol) + Acetate (90 mmol) + Alanine (11.64 g) + Arginine (6.48 g) + Aspartic acid (3.6 g) + Calcium (8 mmol) + Calcium chloride dihydrate (1.176 g) + Chlorine (90 mmol) + D-glucose (300 g) + Glutamic acid (8.42 g) + Glycine (3.96 g) + Histidine (3 g) + Isoleucine (5.64 g) + Leucine (7.52 g) + Lysine (5.46 g) + Magnesium (8 mmol) + Magnesium acetate tetrahydrate (1.716 g) + Medium-chain triglycerides (50 g) + Methionine (4.7 g) + Phenylalanine (8.42 g) + Potassium (70 mmol) + Potassium acetate (6.868 g) + Proline (8.16 g) + Serine (7.2 g) + Sodium acetate trihydrate (0.554 g) + Sodium cation (100 mmol) + Sodium chloride (1.006 g) + Sodium hydroxide (1.952 g) + Sodium phosphate, monobasic, dihydrate (4.68 g) + Soybean oil (50 g) + Threonine (4.36 g) + Tryptophan (1.36 g) + Valine (6.24 g) + Zinc (0.06 mmol) + Zinc acetate dihydrate (13.16 mg)	Injection, emulsion	Intravenous	B.BRAUN MEDİKAL DIŞ TİC. A.Ş.	2020-08-14	2018-10-03
NUTRIFLEX LIPID SPECIAL INTRAVENOZ INFUZYONLUK EMULSIYON, 1250 ML	Phosphate ion (15 mmol) + Acetate (45 mmol) + Alanine (5.82 g) + Arginine (3.24 g) + Aspartic acid (1.8 g) + Calcium (4 mmol) + Calcium chloride dihydrate (0.588 g) + Chlorine (45 mmol) + D-glucose (150 g) + Glutamic acid (4.21 g) + Glutamic acid (1.98 g) + Histidine (2.03 g) + Isoleucine (2.82 g) + Leucine (3.76 g) + Lysine (2.73 g) + Magnesium (4 mmol) + Magnesium acetate tetrahydrate (0.858 g) + Medium-chain triglycerides (25 g) + Methionine (2.35 g) + Phenylalanine (4.21 g) + Potassium (35 mmol) + Potassium acetate (3.434 g) + Proline (4.08 g) + Serine (3.6 g) + Sodium acetate trihydrate (0.277 g) + Sodium cation (50 mmol) + Sodium chloride (0.503 g) + Sodium hydroxide (0.976 g) + Sodium phosphate, monobasic, dihydrate (2.34 g) + Soybean oil (25 g) + Threonine (2.18 g) + Tryptophan (0.68 g) + Valine (3.12 g) + Zinc (0.03 mmol) + Zinc acetate dihydrate (6.58 mg)	Emulsion	Intravenous	B.BRAUN MEDİKAL DIŞ TİC. A.Ş.	2007-07-03	2018-10-03
NUTRIFLEX LIPID SPECIAL INTRAVENOZ INFUZYONLUK EMULSIYON, 1875 ML	Phosphate ion (22.5 mmol) + Acetate (67.5 mmol) + Alanine (8.73 g) + Arginine (4.86 g) + Aspartic acid (2.7 g) + Calcium (6 mmol) + Calcium chloride dihydrate (0.882 g) + Chlorine (67.5 mmol) + D-glucose (225 g) + Glutamic acid (6.32 g) + Glutamic acid (2.97 g) + Histidine (3.05 g) + Isoleucine (4.23 g) + Leucine (5.64 g) + Lysine (4.1 g) + Magnesium (6 mmol) + Magnesium acetate tetrahydrate (1.287 g) + Medium-chain triglycerides (37.5 g) + Methionine (3.53 g) + Phenylalanine (6.32 g) + Potassium (52.5 mmol) + Potassium acetate (5.151 g) + Proline (6.12 g) + Serine (5.4 g) + Sodium acetate trihydrate (0.416 g) + Sodium cation (75 mmol) + Sodium chloride (0.755 g) + Sodium hydroxide (1.464 g) + Sodium phosphate, monobasic, dihydrate (3.51 g) + Soybean oil (37.5 g) + Threonine (3.27 g) + Tryptophan (1.02 g) + Valine (4.68 g) + Zinc (0.045 mmol) + Zinc acetate dihydrate (9.87 mg)	Emulsion	Intravenous	B.BRAUN MEDİKAL DIŞ TİC. A.Ş.	2007-07-03	2018-10-03

Unapproved/Other Products

Name	Ingredients	Dosage	Route	Labeller	Marketing Start	Marketing End	Region	Image
Liquidguard	Phosphate ion (2.5 g/100mL)	Liquid	Topical	Nano Care Deutschland AG	2020-03-30	Not applicable

Categories

Drug Categories

• Acids
• Acids, Noncarboxylic
• Anions
• Electrolytes
• Ions
• Phosphate salts
• Phosphoric Acids
• Phosphorus Acids
• Phosphorus Compounds

Chemical TaxonomyProvided by Classyfire

Description

This compound belongs to the class of inorganic compounds known as non-metal phosphates. These are inorganic non-metallic compounds containing a phosphate as its largest oxoanion.

Kingdom

Inorganic compounds

Super Class

Homogeneous non-metal compounds

Class

Non-metal oxoanionic compounds

Sub Class

Non-metal phosphates

Direct Parent

Non-metal phosphates

Alternative Parents

Inorganic oxides

Substituents

Inorganic oxide / Non-metal phosphate

Molecular Framework

Not Available

External Descriptors

trivalent inorganic anion, phosphate ion (CHEBI:18367)

Affected organisms

Not Available

Chemical Identifiers

UNII

NK08V8K8HR

CAS number

14265-44-2

InChI Key

NBIIXXVUZAFLBC-UHFFFAOYSA-K

InChI

InChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)/p-3

IUPAC Name

phosphate

SMILES

[O-]P([O-])([O-])=O

References

General References

Not Available

External Links

Human Metabolome Database

HMDB0001429

ChemSpider

1032

BindingDB

50155537

RxNav

486961

ChEBI

18367

PDBe Ligand

PO4

Wikipedia

Phosphate

PDB Entries

117e / 13pk / 151l / 1914 / 1a2y / 1a40 / 1a6q / 1a7k / 1a9o / 1a9p …

show 7392 more

Clinical Trials

Clinical Trials

Phase	Status	Purpose	Conditions	Count
0	Suspended	Treatment	HHRH / Hypercalcinuria / Hypophosphatemia / Rickets / X-Linked Hypophosphatemia	1
Not Available	Completed	Other	Chronic Kidney Disease (CKD)	1

Pharmacoeconomics

Manufacturers

Not Available

Packagers

Not Available

Dosage Forms

Form	Route	Strength
Liquid	Topical	2.5 g/100mL
Injection, emulsion	Intravenous
Emulsion	Intravenous

Prices

Not Available

Patents

Not Available

Properties

State

Not Available

Experimental Properties

Not Available

Predicted Properties

Property	Value	Source
logP	-1	Chemaxon
pKa (Strongest Acidic)	1.8	Chemaxon
Physiological Charge	-2	Chemaxon
Hydrogen Acceptor Count	4	Chemaxon
Hydrogen Donor Count	0	Chemaxon
Polar Surface Area	86.25 Å2	Chemaxon
Rotatable Bond Count	0	Chemaxon
Refractivity	11.29 m3·mol-1	Chemaxon
Polarizability	4.93 Å3	Chemaxon
Number of Rings	0	Chemaxon
Bioavailability	1	Chemaxon
Rule of Five	Yes	Chemaxon
Ghose Filter	No	Chemaxon
Veber's Rule	No	Chemaxon
MDDR-like Rule	No	Chemaxon

Predicted ADMET Features

Not Available

Spectra

Mass Spec (NIST)

Not Available

Spectra

Not Available

Chromatographic Properties

Collision Cross Sections (CCS)

Adduct	CCS Value (Å2)	Source type	Source
[M-H]-	105.4805532	predicted	DarkChem Lite v0.1.0
[M-H]-	111.7231	predicted	DeepCCS 1.0 (2019)
[M-H]-	105.4805532	predicted	DarkChem Lite v0.1.0
[M-H]-	111.7231	predicted	DeepCCS 1.0 (2019)
[M+H]+	113.752655	predicted	DeepCCS 1.0 (2019)
[M+H]+	113.752655	predicted	DeepCCS 1.0 (2019)
[M+Na]+	122.13096	predicted	DeepCCS 1.0 (2019)
[M+Na]+	122.13096	predicted	DeepCCS 1.0 (2019)

×

Identify potential medication risks

Easily compare up to 40 drugs with our drug interaction checker.

Get severity rating, description, and management advice.

Learn more

Drug created at July 12, 2018 19:12 / Updated at June 12, 2020 16:53