Showing BioInteractions for Turoctocog alfa pegol (DB14738)
BioInteractor utilizes data on drug-target, -enzyme and -transporter associations to provide insight on drug-drug interactions. It allows you to identify, for instance, which drugs act similarly on the same target. Such drugs may have additive pharmacodynamic effects if given concomitantly. Conversely, two drugs may antagonize the beneficial effects of each other by having opposite actions on a specific drug target. BioInteractor uses ranked drug-enzyme association information to predict enzyme-mediated drug interactions that may be clinically relevant.
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Turoctocog alfa pegol is a Coagulation factor IX activator | ||
| 1 | Coagulation factor IX activators | Antihemophilic factor human, Coagulation factor VII human, Menadione, Turoctocog alfa |
| 2 | Coagulation factor IX cofactors | Antihemophilic factor, human recombinant, Emicizumab, Lonoctocog alfa, Moroctocog alfa |
| 3 | Coagulation factor IX substrates | Anti-inhibitor coagulant complex |
| 4 | Coagulation factor IX agonists | Kappadione |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Turoctocog alfa pegol is a Coagulation factor X activator | ||
| 1 | Coagulation factor X activators | Albutrepenonacog alfa, Antihemophilic factor human, Antihemophilic factor, human recombinant, Coagulation Factor IX (Recombinant), Coagulation Factor IX Human, Coagulation factor VII human, Emicizumab, Lonoctocog alfa, Moroctocog alfa, Turoctocog alfa |
| 2 | Coagulation factor X inhibitors | Antithrombin Alfa, Apixaban, Betrixaban, Edoxaban, Enoxaparin, Fondaparinux, Heparin, Nafamostat |
| 3 | Coagulation factor X antagonists | Bemiparin, Protein S human, Rivaroxaban |
| 4 | Coagulation factor X substrates | Prothrombin, Turoctocog alfa pegol |
| 5 | Coagulation factor X agonists | Anti-inhibitor coagulant complex, Kappadione, Nonacog beta pegol |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Turoctocog alfa pegol is a Prothrombin binder | ||
| 1 | Prothrombin inhibitors | Antithrombin Alfa, Argatroban, Betrixaban, Bivalirudin, Conestat alfa, Dabigatran etexilate, Gabexate, Human C1-esterase inhibitor, Lepirudin, Nafamostat, Suramin, Thrombomodulin Alfa, Ximelagatran |
| 2 | Prothrombin activators | Antihemophilic factor, human recombinant, Lonoctocog alfa, Menadione, Moroctocog alfa |
| 3 | Prothrombin agonists | Anti-inhibitor coagulant complex, Kappadione |
| 4 | Prothrombin substrates | Anti-inhibitor coagulant complex |
| 5 | Prothrombin binders | Turoctocog alfa |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Turoctocog alfa pegol is a Vitamin K-dependent protein C substrate | ||
| 1 | Vitamin K-dependent protein C inhibitors | Sodium tetradecyl sulfate |
| 2 | Vitamin K-dependent protein C activators | Menadione |
| 3 | Vitamin K-dependent protein C inactivators | Antihemophilic factor, human recombinant, Lonoctocog alfa, Moroctocog alfa |
| 4 | Vitamin K-dependent protein C cofactors | Protein S human |
| 5 | Vitamin K-dependent protein C substrates | Antihemophilic factor human |
| 6 | Vitamin K-dependent protein C agonists | Kappadione |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Turoctocog alfa pegol is a Coagulation factor X substrate | ||
| 1 | Coagulation factor X activators | Albutrepenonacog alfa, Antihemophilic factor human, Antihemophilic factor, human recombinant, Coagulation Factor IX (Recombinant), Coagulation Factor IX Human, Coagulation factor VII human, Emicizumab, Lonoctocog alfa, Moroctocog alfa, Turoctocog alfa, Turoctocog alfa pegol |
| 2 | Coagulation factor X inhibitors | Antithrombin Alfa, Apixaban, Betrixaban, Edoxaban, Enoxaparin, Fondaparinux, Heparin, Nafamostat |
| 3 | Coagulation factor X antagonists | Bemiparin, Protein S human, Rivaroxaban |
| 4 | Coagulation factor X substrates | Prothrombin |
| 5 | Coagulation factor X agonists | Anti-inhibitor coagulant complex, Kappadione, Nonacog beta pegol |