Pegzilarginase
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This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Generic Name
- Pegzilarginase
- DrugBank Accession Number
- DB14780
- Background
Pegzilarginase is under investigation in clinical trial NCT02488044 (A Phase 1/2 Study of AEB1102 in Patients With Arginase I Deficiency).
- Type
- Biotech
- Groups
- Investigational
- Synonyms
- AEB-1102
- AEB1102
- Co-ArgI-PEG
- Co-ArgI-PEG modified human arginase I
- Optimised human arginase I
- PEG-arginase
- Pegarginase
- Pegzilarginase
- External IDs
- AEB1102
Pharmacology
- Indication
Not Available
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- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
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- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Categories
- ATC Codes
- A16AB24 — Pegzilarginase
- Drug Categories
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- 4YV4KW88GD
- CAS number
- 1659310-95-8
References
- General References
- Not Available
- External Links
- Not Available
Clinical Trials
- Clinical Trials
Phase Status Purpose Conditions Count 3 Completed Treatment Arginase deficiency / Arginase I Deficiency 1 3 Terminated Treatment Arginase deficiency / Arginase I Deficiency 1 2 Completed Treatment Acute Myeloid Leukemia / Myelodysplastic Syndrome 1 2 Completed Treatment Arginase deficiency / Arginase I Deficiency 1 1, 2 Completed Treatment Advanced Malignant Neoplasm 1
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
- Not Available
- Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
Drug created at May 20, 2019 14:26 / Updated at April 20, 2023 07:02