Cefiderocol

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

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Name
Cefiderocol
Accession Number
DB14879
Type
Small Molecule
Groups
Investigational
Description

Cefiderocol is under investigation in clinical trial NCT02321800 (A Study of Efficacy/Safety of Intravenous S-649266 Versus Imipenem/Cilastatin in Complicated Urinary Tract Infections).

Structure
Thumb
Synonyms
Not Available
External IDs
S-649266
Categories
UNII
SZ34OMG6E8
CAS number
1225208-94-5
Weight
Average: 752.21
Monoisotopic: 751.1497104
Chemical Formula
C30H34ClN7O10S2
InChI Key
DBPPRLRVDVJOCL-FQRUVTKNSA-N
InChI
InChI=1S/C30H34ClN7O10S2/c1-30(2,28(46)47)48-36-19(16-13-50-29(32)34-16)24(42)35-20-25(43)37-21(27(44)45)14(12-49-26(20)37)11-38(8-3-4-9-38)10-7-33-23(41)15-5-6-17(39)22(40)18(15)31/h5-6,13,20,26H,3-4,7-12H2,1-2H3,(H7-,32,33,34,35,36,39,40,41,42,44,45,46,47)/t20-,26-/m1/s1
IUPAC Name
SMILES
CC(C)(O\N=C(/C(=O)N[C@H]1[C@H]2SCC(C[N+]3(CCNC(=O)C4=C(Cl)C(O)=C(O)C=C4)CCCC3)=C(N2C1=O)C([O-])=O)C1=CSC(N)=N1)C(O)=O

Pharmacology

Indication
Not Available
Pharmacodynamics
Not Available
Mechanism of action
Not Available
Absorption
Not Available
Volume of distribution
Not Available
Protein binding
Not Available
Metabolism
Not Available
Route of elimination
Not Available
Half life
Not Available
Clearance
Not Available
Toxicity
Not Available
Affected organisms
Not Available
Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

References

General References
Not Available
External Links
ChemSpider
52084902
ChEMBL
CHEMBL3989974
Wikipedia
Cefiderocol

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
1RecruitingTreatmentPneumonia, Bacterial1
2CompletedTreatmentUrinary Tract Infections (UTIs)1
2Not Yet RecruitingTreatmentBloodstream Infections1
3Active Not RecruitingTreatmentBloodstream Infections (BSI) / Complicated Urinary Tract Infections (cUTIs) / Healthcare-associated Pneumonia (HCAP) / Hospital-acquired bacterial pneumonia / Sepsis / Ventilator-associated Bacterial Pneumonia1
3CompletedTreatmentHealthcare-associated Pneumonia (HCAP) / Hospital-acquired bacterial pneumonia / Ventilator-associated Bacterial Pneumonia1
Not AvailableAvailableNot AvailableBacterial Infections1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Predicted ADMET features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Not Available

Taxonomy

Classification
Not classified

Drug created on May 20, 2019 08:32 / Updated on September 02, 2019 20:24