Showing BioInteractions for Cefiderocol (DB14879)
BioInteractor utilizes data on drug-target, -enzyme and -transporter associations to provide insight on drug-drug interactions. It allows you to identify, for instance, which drugs act similarly on the same target. Such drugs may have additive pharmacodynamic effects if given concomitantly. Conversely, two drugs may antagonize the beneficial effects of each other by having opposite actions on a specific drug target. BioInteractor uses ranked drug-enzyme association information to predict enzyme-mediated drug interactions that may be clinically relevant.
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Cefiderocol is a Penicillin-binding protein 3 inhibitor | ||
| 1 | Penicillin-binding protein 3 inhibitors | Cefepime, Ceftolozane, Cloxacillin, Doripenem |
| 2 | Penicillin-binding protein 3 antagonists | Doripenem |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Cefiderocol is a Penicillin-binding protein 1A inhibitor | ||
| 1 | Penicillin-binding protein 1A inhibitors | Cefoperazone, Cefpiramide |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Cefiderocol is a Penicillin-binding protein 1B inhibitor | ||
| 1 | Penicillin-binding protein 1B inhibitors | Cefoperazone, Cefpiramide, Ceftazidime, Ceftolozane |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Cefiderocol is a Penicillin-binding protein 2 inhibitor | ||
| 1 | Penicillin-binding protein 2 inhibitors | Cefepime, Ceftazidime |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Cefiderocol is a D-alanyl-D-alanine carboxypeptidase DacB inhibitor | ||
| 1 | D-alanyl-D-alanine carboxypeptidase DacB inhibitors | Cefonicid, Cefoperazone, Cefoxitin, Ertapenem, Latamoxef, Meropenem |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Cefiderocol is a MexAB-OprM efflux system substrate | ||
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Cefiderocol is a Catecholate siderophore receptor Fiu substrate | ||
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Cefiderocol is a Colicin I receptor substrate | ||
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Cefiderocol is a Putative outer membrane ferric siderophore receptor substrate | ||