Nicotinamide riboside

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

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Name
Nicotinamide riboside
Accession Number
DB14933
Type
Small Molecule
Groups
Investigational
Description

Nicotinamide riboside is under investigation in clinical trial NCT03432871 (Nicotinamide Riboside and Mitochondrial Biogenesis).

Structure
Thumb
Synonyms
Not Available
Categories
UNII
0I8H2M0L7N
CAS number
1341-23-7
Weight
Average: 255.2472
Monoisotopic: 255.0980966
Chemical Formula
C11H15N2O5
InChI Key
JLEBZPBDRKPWTD-TURQNECASA-O
InChI
InChI=1S/C11H14N2O5/c12-10(17)6-2-1-3-13(4-6)11-9(16)8(15)7(5-14)18-11/h1-4,7-9,11,14-16H,5H2,(H-,12,17)/p+1/t7-,8-,9-,11-/m1/s1
IUPAC Name
SMILES
NC(=O)C1=C[N+](=CC=C1)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O

Pharmacology

Indication
Not Available
Pharmacodynamics
Not Available
Mechanism of action
Not Available
Absorption
Not Available
Volume of distribution
Not Available
Protein binding
Not Available
Metabolism
Not Available
Route of elimination
Not Available
Half life
Not Available
Clearance
Not Available
Toxicity
Not Available
Affected organisms
Not Available
Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
Not Available
Food Interactions
Not Available

References

General References
Not Available
External Links
Human Metabolome Database
HMDB0000855
KEGG Compound
C03150
ChemSpider
388956
ChEBI
15927
ChEMBL
CHEMBL438497
HET
NNR
Wikipedia
Nicotinamide_riboside
PDB Entries
2qt0 / 2qt1 / 4qtn / 6gye

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
1, 2RecruitingTreatmentDiabetic Peripheral Neuropathy (DPN)1
1, 2RecruitingTreatmentMild Cognitive Impairment (MCI)1
2Not Yet RecruitingPreventionSmall Fibre Neuropathy1
2Not Yet RecruitingTreatmentBlood Pressures / Kidney Diseases / Oxidative Stress / Vascular Diseases1
2RecruitingTreatmentAging / High Blood Pressure (Hypertension)1
2RecruitingTreatmentBreast Cancer Metastatic / Chemotherapy-induced Peripheral Neuropathy (CIPN)1
3RecruitingTreatmentPeripheral Artery Disease (PAD)1
4RecruitingTreatmentHealthy Volunteers1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Predicted ADMET features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
SpectrumSpectrum TypeSplash Key
Predicted GC-MS Spectrum - GC-MSPredicted GC-MSNot Available
Predicted MS/MS Spectrum - 10V, Positive (Annotated)Predicted LC-MS/MSsplash10-0a4i-0090000000-e25d1beb47cb1fe9e4cb
Predicted MS/MS Spectrum - 20V, Positive (Annotated)Predicted LC-MS/MSsplash10-002b-3090000000-03687e9ef697eda1d6c8
Predicted MS/MS Spectrum - 40V, Positive (Annotated)Predicted LC-MS/MSsplash10-052g-9300000000-2755bde4df843d2227f2
Predicted MS/MS Spectrum - 10V, Negative (Annotated)Predicted LC-MS/MSsplash10-0udi-0090000000-809be1146b2a2c8d96a7
Predicted MS/MS Spectrum - 20V, Negative (Annotated)Predicted LC-MS/MSsplash10-0udi-1390000000-2fc72cf0619f182e044f
Predicted MS/MS Spectrum - 40V, Negative (Annotated)Predicted LC-MS/MSsplash10-0k96-9300000000-4d5b96b192f3484b1b8a

Taxonomy

Classification
Not classified

Drug created on May 20, 2019 08:36 / Updated on May 21, 2019 12:31