Seltorexant

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

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Name
Seltorexant
Accession Number
DB14961
Type
Small Molecule
Groups
Investigational
Description

Seltorexant is under investigation in clinical trial NCT03494907 (A Study to Evaluate the Effects of Single-dose Seltorexant on Electrocardiogram Intervals in Healthy Adult Participants).

Structure
Thumb
Synonyms
  • JNJ-42847922
Categories
Not Available
UNII
AIS8N3O50B
CAS number
1452539-75-1
Weight
Average: 407.453
Monoisotopic: 407.186986519
Chemical Formula
C21H22FN7O
InChI Key
SQOCEMCKYDVLMM-IYBDPMFKSA-N
InChI
InChI=1S/C21H22FN7O/c1-13-8-14(2)26-21(25-13)28-11-15-9-27(10-16(15)12-28)20(30)19-17(22)4-3-5-18(19)29-23-6-7-24-29/h3-8,15-16H,9-12H2,1-2H3/t15-,16+
IUPAC Name
SMILES
CC1=CC(C)=NC(=N1)N1C[C@@H]2CN(C[C@@H]2C1)C(=O)C1=C(F)C=CC=C1N1N=CC=N1

Pharmacology

Indication
Not Available
Pharmacodynamics
Not Available
Mechanism of action
Not Available
Absorption
Not Available
Volume of distribution
Not Available
Protein binding
Not Available
Metabolism
Not Available
Route of elimination
Not Available
Half life
Not Available
Clearance
Not Available
Toxicity
Not Available
Affected organisms
Not Available
Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
Not Available
Food Interactions
Not Available

References

General References
Not Available
External Links
ChemSpider
34989176
BindingDB
50092814
ChEMBL
CHEMBL3586436
Wikipedia
Seltorexant

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
1CompletedOtherHealthy Volunteers2
1CompletedTreatmentHealthy Volunteers8
1CompletedTreatmentMajor Depressive Disorder (MDD)3
1CompletedTreatmentSleep Apnea, Obstructive1
1RecruitingOtherHealthy Volunteers1
2Active Not RecruitingTreatmentMajor Depressive Disorder (MDD)1
2CompletedTreatmentInsomnia Disorders1
2CompletedTreatmentMajor Depressive Disorder (MDD)1
2CompletedTreatmentSleeplessness1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Predicted ADMET features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Not Available

Taxonomy

Classification
Not classified

Drug created on May 20, 2019 08:38 / Updated on May 21, 2019 12:32