Pimodivir

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

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Name
Pimodivir
Accession Number
DB14974
Type
Small Molecule
Groups
Investigational
Description

Pimodivir is under investigation in clinical trial NCT02658825 (A Study to Evaluate the Effect of JNJ-63623872 on Cardiac Repolarization Interval in Healthy Participants).

Structure
Thumb
Synonyms
  • JNJ-63623872
Categories
Not Available
UNII
DFC121MXC3
CAS number
1629869-44-8
Weight
Average: 399.402
Monoisotopic: 399.150681198
Chemical Formula
C20H19F2N5O2
InChI Key
JGPXDNKSIXAZEQ-SBBZOCNPSA-N
InChI
InChI=1S/C20H19F2N5O2/c21-11-5-12-13(7-24-17(12)23-6-11)18-25-8-14(22)19(27-18)26-16-10-3-1-9(2-4-10)15(16)20(28)29/h5-10,15-16H,1-4H2,(H,23,24)(H,28,29)(H,25,26,27)/t9?,10?,15-,16-/m0/s1
IUPAC Name
SMILES
OC(=O)[C@H]1C2CCC(CC2)[C@@H]1NC1=C(F)C=NC(=N1)C1=CNC2=C1C=C(F)C=N2

Pharmacology

Indication
Not Available
Pharmacodynamics
Not Available
Mechanism of action
Not Available
Absorption
Not Available
Volume of distribution
Not Available
Protein binding
Not Available
Metabolism
Not Available
Route of elimination
Not Available
Half life
Not Available
Clearance
Not Available
Toxicity
Not Available
Affected organisms
Not Available
Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
Not Available
Food Interactions
Not Available

References

General References
Not Available
External Links
ChemSpider
58136671
BindingDB
50050712
ChEMBL
CHEMBL3318007

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
1CompletedNot AvailableHealthy Volunteers2
1CompletedOtherHealthy Volunteers1
1CompletedTreatmentHealthy Volunteers5
1CompletedTreatmentInfluenza A Virus1
1CompletedTreatmentInfluenza in Humans1
1Not Yet RecruitingOtherChronic Renal Failure (CRF)1
1RecruitingOtherHepatic Impairment1
2CompletedTreatmentInfluenza A Virus1
3RecruitingTreatmentInfluenza A Virus Infection2
Not AvailableAvailableNot AvailableH7N9 Subtype of Influenza A Virus1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Predicted ADMET features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Not Available

Taxonomy

Classification
Not classified

Drug created on May 20, 2019 08:38 / Updated on May 21, 2019 12:32