Nemorexant

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

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Name
Nemorexant
Accession Number
DB15031
Type
Small Molecule
Groups
Investigational
Description

Nemorexant is under investigation in clinical trial NCT03101189 (A Study of ACT-541468 in Healthy Japanese and Caucasian Subjects).

Structure
Thumb
Synonyms
  • ACT-541468
Categories
Not Available
UNII
LMQ24G57E9
CAS number
1505484-82-1
Weight
Average: 450.93
Monoisotopic: 450.1571017
Chemical Formula
C23H23ClN6O2
InChI Key
NBGABHGMJVIVBW-QHCPKHFHSA-N
InChI
InChI=1S/C23H23ClN6O2/c1-14-17(24)6-7-18-20(14)28-22(27-18)23(2)9-4-12-29(23)21(31)16-13-15(32-3)5-8-19(16)30-25-10-11-26-30/h5-8,10-11,13H,4,9,12H2,1-3H3,(H,27,28)/t23-/m0/s1
IUPAC Name
SMILES
COC1=CC(C(=O)N2CCC[C@@]2(C)C2=NC3=C(N2)C=CC(Cl)=C3C)=C(C=C1)N1N=CC=N1

Pharmacology

Indication
Not Available
Pharmacodynamics
Not Available
Mechanism of action
Not Available
Absorption
Not Available
Volume of distribution
Not Available
Protein binding
Not Available
Metabolism
Not Available
Route of elimination
Not Available
Half life
Not Available
Clearance
Not Available
Toxicity
Not Available
Affected organisms
Not Available
Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
Not Available
Food Interactions
Not Available

References

General References
Not Available
External Links
ChemSpider
64854514
Wikipedia
Nemorexant

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
1Active Not RecruitingOtherHepatic Impairment1
1CompletedOtherHealthy Volunteers7
1CompletedTreatmentHealthy Volunteers1
1Not Yet RecruitingTreatmentHepatic Impairment1
1RecruitingOtherHealthy Volunteers1
1RecruitingTreatmentChronic Obstructive Pulmonary Disease (COPD)1
1RecruitingTreatmentHealthy Recreational Drug Users1
1RecruitingTreatmentObstructive Sleep Apnea (OSA)1
2CompletedTreatmentInsomnia Disorder2
3RecruitingTreatmentInsomnia Disorder3

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Predicted ADMET features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Not Available

Taxonomy

Classification
Not classified

Drug created on May 20, 2019 08:43 / Updated on May 21, 2019 12:34