Omidenepag isopropyl

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

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Name
Omidenepag isopropyl
Accession Number
DB15071
Type
Small Molecule
Groups
Investigational
Description

Omidenepag isopropyl is under investigation in clinical trial NCT02179008 (Multi-center Phase II Study Assessing the Safety and Efficacy of DE-117 Ophthalmic Solution in Subjects With Primary Open-angle Glaucoma or Ocular Hypertension).

Structure
Thumb
Synonyms
Not Available
External IDs
DE-117
Categories
Not Available
UNII
G0G0H52U6K
CAS number
1187451-19-9
Weight
Average: 520.61
Monoisotopic: 520.18927458
Chemical Formula
C26H28N6O4S
InChI Key
VIQCWEGEHRBLAC-UHFFFAOYSA-N
InChI
InChI=1S/C26H28N6O4S/c1-20(2)36-26(33)17-28-25-8-3-6-22(30-25)19-31(37(34,35)24-7-4-13-27-16-24)18-21-9-11-23(12-10-21)32-15-5-14-29-32/h3-16,20H,17-19H2,1-2H3,(H,28,30)
IUPAC Name
SMILES
CC(C)OC(=O)CNC1=CC=CC(CN(CC2=CC=C(C=C2)N2C=CC=N2)S(=O)(=O)C2=CC=CN=C2)=N1

Pharmacology

Indication
Not Available
Pharmacodynamics
Not Available
Mechanism of action
Not Available
Absorption
Not Available
Volume of distribution
Not Available
Protein binding
Not Available
Metabolism
Not Available
Route of elimination
Not Available
Half life
Not Available
Clearance
Not Available
Toxicity
Not Available
Affected organisms
Not Available
Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
Not Available
Food Interactions
Not Available

References

General References
Not Available
External Links
ChemSpider
57643658

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
1CompletedBasic ScienceHealthy Male Adults1
1, 2CompletedTreatmentGlaucoma and Ocular Hypertension1
2CompletedTreatmentOcular Hypertension / Open-angle Glaucoma (OAG)1
2CompletedTreatmentOpen-angle Glaucoma or Ocular Hypertension1
2, 3CompletedTreatmentGlaucoma, Primary Open Angle (POAG) / Ocular Hypertension1
3CompletedTreatmentOpen Angle Glaucoma or Ocular Hypertension2
3CompletedTreatmentPrimary Open Angle Glaucoma or Ocular Hypertension1
3RecruitingTreatmentGlaucoma and Ocular Hypertension2
3RecruitingTreatmentGlaucoma, Primary Open Angle (POAG) / Primary Open-angle Glaucoma and Ocular Hypertension / Primary Open-Angle Glaucoma, Ocular Hypertension1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Predicted ADMET features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Not Available

Taxonomy

Classification
Not classified

Drug created on May 20, 2019 08:47 / Updated on May 21, 2019 12:34