Tirzepatide

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

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Name
Tirzepatide
Accession Number
DB15171
Type
Biotech
Groups
Investigational
Description

Tirzepatide is under investigation in clinical trial NCT03311724 (A Study of Tirzepatide (LY3298176) in Participants With Type 2 Diabetes).

Synonyms
Not Available
External IDs
LY3298176
Categories
UNII
OYN3CCI6QE
CAS number
2023788-19-2

Pharmacology

Indication
Not Available
Pharmacodynamics
Not Available
Mechanism of action
Not Available
Absorption
Not Available
Volume of distribution
Not Available
Protein binding
Not Available
Metabolism
Not Available
Route of elimination
Not Available
Half life
Not Available
Clearance
Not Available
Toxicity
Not Available
Affected organisms
Not Available
Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
DrugInteraction
2,4-thiazolidinedioneThe risk or severity of hypoglycemia can be increased when 2,4-thiazolidinedione is combined with Tirzepatide.
5-(2-methylpiperazine-1-sulfonyl)isoquinolineThe therapeutic efficacy of Tirzepatide can be increased when used in combination with 5-(2-methylpiperazine-1-sulfonyl)isoquinoline.
7,8-Dichloro-1,2,3,4-tetrahydroisoquinoline7,8-Dichloro-1,2,3,4-tetrahydroisoquinoline may increase the hypoglycemic activities of Tirzepatide.
AcarboseThe risk or severity of hypoglycemia can be increased when Acarbose is combined with Tirzepatide.
AcebutololThe therapeutic efficacy of Tirzepatide can be increased when used in combination with Acebutolol.
AcetazolamideThe therapeutic efficacy of Tirzepatide can be increased when used in combination with Acetazolamide.
AcetohexamideThe risk or severity of hypoglycemia can be increased when Acetohexamide is combined with Tirzepatide.
Acetyl sulfisoxazoleThe therapeutic efficacy of Tirzepatide can be increased when used in combination with Acetyl sulfisoxazole.
Acetylsalicylic acidThe risk or severity of hypoglycemia can be increased when Acetylsalicylic acid is combined with Tirzepatide.
AgmatineThe risk or severity of hypoglycemia can be increased when Agmatine is combined with Tirzepatide.
Additional Data Available
  • Extended Description
    Extended Description

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  • Severity
    Severity

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  • Evidence Level
    Evidence Level

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  • Action
    Action

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Food Interactions
Not Available

References

General References
Not Available
External Links
Not Available

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
1Active Not RecruitingBasic ScienceHealthy Volunteers1
1CompletedBasic ScienceEnd Stage Renal Disease (ESRD) / Impaired kidney function1
1CompletedBasic ScienceHealthy Volunteers1
1CompletedBasic ScienceHealthy Volunteers / Type 2 Diabetes Mellitus1
1CompletedBasic ScienceType 2 Diabetes Mellitus1
1Not Yet RecruitingBasic ScienceBMI >30 kg/m21
1Not Yet RecruitingBasic ScienceHealthy Volunteers1
1Not Yet RecruitingBasic ScienceHepatic Insufficiency1
1Not Yet RecruitingBasic ScienceHypoglycemia / Type 2 Diabetes Mellitus1
1RecruitingBasic ScienceHealthy Volunteers1
1RecruitingBasic ScienceType 2 Diabetes Mellitus1
2CompletedTreatmentType 2 Diabetes Mellitus2
2RecruitingTreatmentNonalcoholic Steatohepatitis1
3Not Yet RecruitingTreatmentBMI >27 kg/m2 / BMI >30 kg/m21
3Not Yet RecruitingTreatmentType 2 Diabetes Mellitus1
3RecruitingTreatmentType 2 Diabetes Mellitus7

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available

Taxonomy

Classification
Not classified

Drug created on May 20, 2019 08:55 / Updated on November 02, 2019 03:30