Flotetuzumab

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name
Flotetuzumab
DrugBank Accession Number
DB15223
Background

Flotetuzumab is under investigation in clinical trial NCT02152956 (Safety Study of MGD006 in Relapsed/Refractory Acute Myeloid Leukemia (AML) or Intermediate-2/High Risk MDS).

Type
Biotech
Groups
Investigational
Synonyms
  • Flotetuzumab

Pharmacology

Indication

Not Available

Reduce drug development failure rates
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Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Categories

Drug Categories
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
0AHT0IC02G
CAS number
1664355-28-5

References

General References
Not Available
Wikipedia
Flotetuzumab

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
2RecruitingTreatmentRelapsed Acute Myelogenous Leukemia (AML)1
2WithdrawnTreatmentAcute Biphenotypic Leukemia (ABL) / Acute Leukemia / Hairy Cell Leukemia (HCL) / Interleukin-3 Receptor Subunit Alpha Positive / Philadelphia Chromosome Positive (Ph+) Chronic Myeloid Leukemia (CML) / Recurrent Acute Lymphoblastic Leukemia (ALL) / Recurrent Blastic Plasmacytoid Dendritic Cell Neoplasm / Recurrent Chronic Myelogenous Leukemia, BCR-ABL1 Positive / Recurrent Hematologic Malignancy / Recurrent Hodgkin Lymphoma / Refractory Acute Lymphoblastic Leukemia (ALL) / Refractory Blastic Plasmacytoid Dendritic Cell Neoplasm / Refractory Hematologic Malignancy / Refractory Hodgkin Lymphoma / Systemic Mastocytosis1
2WithdrawnTreatmentAcute Myeloid Leukemia1
1Active Not RecruitingTreatmentRecurrent Acute Leukemia / Recurrent B Acute Lymphoblastic Leukemia / Recurrent Blastic Plasmacytoid Dendritic Cell Neoplasm / Recurrent Chronic Myelogenous Leukemia, BCR-ABL1 Positive / Recurrent Hairy Cell Leukemia / Recurrent Hematologic Malignancy / Recurrent Hodgkin Lymphoma / Recurrent T-cell Acute Lymphoblastic Leukemia / Refractory Acute Leukemia / Refractory B Cell Acute Lymphoblastic Leukemia (ALL) / Refractory Blastic Plasmacytoid Dendritic Cell Neoplasm / Refractory Chronic Myelogenous Leukemia, BCR-ABL1 Positive / Refractory Hairy Cell Leukemia / Refractory Hematologic Malignancy / Refractory Hodgkin Lymphoma / Refractory T-cell Acute Lymphoblastic Leukemia / Systemic Mastocytosis1
1Active Not RecruitingTreatmentRecurrent Acute Myeloid Leukemia / Refractory Acute Myeloid Leukemia (AML)1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available

Drug created at May 20, 2019 15:01 / Updated at February 21, 2021 18:55