Menaquinone

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

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Name
Menaquinone
Accession Number
DB15381
Type
Small Molecule
Groups
Investigational
Description

Menaquinone is under investigation in clinical trial NCT01533441 (Vitamin K2 Intervention in Patients With Vitamin K Antagonists).

Structure
Thumb
Synonyms
Not Available
Categories
UNII
12V8PA4WCH
CAS number
1182-68-9
Weight
Average: 512.778
Monoisotopic: 512.365430786
Chemical Formula
C36H48O2
InChI Key
HYPYXGZDOYTYDR-HAJWAVTHSA-N
InChI
InChI=1S/C36H48O2/c1-26(2)14-10-15-27(3)16-11-17-28(4)18-12-19-29(5)20-13-21-30(6)24-25-32-31(7)35(37)33-22-8-9-23-34(33)36(32)38/h8-9,14,16,18,20,22-24H,10-13,15,17,19,21,25H2,1-7H3/b27-16+,28-18+,29-20+,30-24+
IUPAC Name
SMILES
CC(C)=CCC\C(C)=C\CC\C(C)=C\CC\C(C)=C\CC\C(C)=C\CC1=C(C)C(=O)C2=C(C=CC=C2)C1=O

Pharmacology

Indication
Not Available
Pharmacodynamics
Not Available
Mechanism of action
Not Available
Absorption
Not Available
Volume of distribution
Not Available
Protein binding
Not Available
Metabolism
Not Available
Route of elimination
Not Available
Half life
Not Available
Clearance
Not Available
Toxicity
Not Available
Affected organisms
Not Available
Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
DrugInteraction
Alpha-1-proteinase inhibitorAlpha-1-proteinase inhibitor may increase the thrombogenic activities of Menaquinone.
Aminocaproic AcidAminocaproic Acid may increase the thrombogenic activities of Menaquinone.
Aminomethylbenzoic acidAminomethylbenzoic acid may increase the thrombogenic activities of Menaquinone.
Andexanet alfaMenaquinone may increase the thrombogenic activities of Andexanet alfa.
Anti-inhibitor coagulant complexMenaquinone may increase the thrombogenic activities of Anti-inhibitor coagulant complex.
Antihemophilic Factor (Recombinant), PEGylatedMenaquinone may increase the thrombogenic activities of Antihemophilic Factor (Recombinant), PEGylated.
Antihemophilic factor humanMenaquinone may increase the thrombogenic activities of Antihemophilic factor human.
Antihemophilic factor, human recombinantMenaquinone may increase the thrombogenic activities of Antihemophilic factor, human recombinant.
AprotininAprotinin may increase the thrombogenic activities of Menaquinone.
Beroctocog alfaMenaquinone may increase the thrombogenic activities of Beroctocog alfa.
Additional Data Available
  • Extended Description
    Extended Description

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  • Severity
    Severity

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  • Evidence Level
    Evidence Level

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  • Action
    Action

    An effect category for each drug interaction. Know how this interaction affects the subject drug.

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Food Interactions
Not Available

References

General References
Not Available
External Links
ChemSpider
32815523
Wikipedia
Vitamin_K2

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
2Unknown StatusTreatmentAtherosclerosis / Carotid Disease1
4CompletedTreatmentCalcifications, Vascular1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Predicted ADMET features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Not Available

Taxonomy

Classification
Not classified

Drug created on May 20, 2019 09:22 / Updated on May 21, 2019 12:41