This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Summary
Aluminum subacetate is a medication used to prevent infection and treat irritation around the rectum.
- Generic Name
- Aluminum subacetate
- DrugBank Accession Number
- DB15679
- Background
Not Available
- Type
- Small Molecule
- Groups
- Approved, Experimental
- Structure
Structure for Aluminum subacetate (DB15679)
- Weight
- Average: 162.0769
Monoisotopic: 162.010886775 - Chemical Formula
- C4H7AlO5
- Synonyms
- Aluminum diaceate
- Aluminum diacetate
- Aluminum hydroxyacetate
- Aluminum subacetate
Pharmacology
- Indication
Not Available
Reduce drug development failure ratesBuild, train, & validate machine-learning modelswith evidence-based and structured datasets.Build, train, & validate predictive machine-learning models with structured datasets.- Associated Conditions
Indication Type Indication Combined Product Details Approval Level Age Group Patient Characteristics Dose Form Used in combination for symptomatic treatment of Hemorrhoids Combination Product in combination with: Lidocaine (DB00281), Hydrocortisone acetate (DB14539), Zinc oxide (DB09321) •••••••••••• ••••••••••• Used in combination for symptomatic treatment of Post operative pain Combination Product in combination with: Zinc oxide (DB09321), Lidocaine (DB00281), Hydrocortisone acetate (DB14539) •••••••••••• ••••••••••• Used in combination for symptomatic treatment of Proctitis Combination Product in combination with: Lidocaine (DB00281), Hydrocortisone acetate (DB14539), Zinc oxide (DB09321) •••••••••••• ••••••••••• Used in combination for symptomatic treatment of Pruritus ani Combination Product in combination with: Hydrocortisone acetate (DB14539), Zinc oxide (DB09321), Lidocaine (DB00281) •••••••••••• ••••••••••• Used in combination for symptomatic treatment of Mild anal fissures Combination Product in combination with: Zinc oxide (DB09321), Hydrocortisone acetate (DB14539), Lidocaine (DB00281) •••••••••••• ••••••••••• - Contraindications & Blackbox Warnings
Prevent Adverse Drug Events TodayTap into our Clinical API for life-saving information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.Avoid life-threatening adverse drug events with our Clinical API- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Products
Drug product information from 10+ global regionsOur datasets provide approved product information including:dosage, form, labeller, route of administration, and marketing period.Access drug product information from over 10 global regions.- Mixture Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image Buro Sol Antiseptic Powder Aluminum subacetate (0.35 %) + Benzethonium chloride (0.023 %) Powder Topical Glaxosmithkline Inc 1985-12-31 2016-12-06 Canada 
HEMORALGINE 40 GR POMAD Aluminum subacetate (0.4 g) + Bismuth subgallate (2 g) + Chlorhexidine hydrochloride (0.4 g) + Ephedrine hydrochloride (0.2 g) + Levomenthol (0.8 g) + Tetracaine hydrochloride (0.4 g) + Zinc oxide (3.2 g) Ointment Topical ATABAY İLAÇ FABRİKASI A.Ş. 1991-07-19 Not applicable Turkey 
Categories
- Drug Categories
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- FGL8577C9S
- CAS number
- 142-03-0
- InChI Key
- HQQUTGFAWJNQIP-UHFFFAOYSA-K
- InChI
- InChI=1S/2C2H4O2.Al.H2O/c2*1-2(3)4;;/h2*1H3,(H,3,4);;1H2/q;;+3;/p-3
- IUPAC Name
- (acetyloxy)(hydroxy)alumanyl acetate
- SMILES
- CC(=O)O[Al](O)OC(C)=O
References
- General References
- NPRA Product Information: Xyloproct (Aluminum subacetate / Hydrocortisone acetate / Lidocaine / Zinc oxide) rectal ointment/suppository [Link]
- External Links
- ChemSpider
- 8373332
- 235461
- ChEMBL
- CHEMBL1532734
Clinical Trials
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Lotion Topical 0.059 g Powder Topical Ointment Topical Ointment Suppository Rectal - Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 10.4 mg/mL ALOGPS logP 0.21 ALOGPS logP -0.4 Chemaxon logS -1.2 ALOGPS pKa (Strongest Acidic) 13.58 Chemaxon pKa (Strongest Basic) -3.4 Chemaxon Physiological Charge 0 Chemaxon Hydrogen Acceptor Count 3 Chemaxon Hydrogen Donor Count 1 Chemaxon Polar Surface Area 72.83 Å2 Chemaxon Rotatable Bond Count 4 Chemaxon Refractivity 26 m3·mol-1 Chemaxon Polarizability 13.6 Å3 Chemaxon Number of Rings 0 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Not Available
- Chromatographic Properties
Collision Cross Sections (CCS)
Not Available
Drug created at April 28, 2020 19:51 / Updated at May 14, 2021 01:07