Potassium metabisulfite

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name

DrugBank Accession Number

DB15841

Background

Not Available

Type

Small Molecule

Groups

Experimental

Structure

Similar Structures

Weight: Average: 222.31
Monoisotopic: 221.84612843
Chemical Formula: K₂O₅S₂

Synonyms

Potassium disulfite
Potassium metabisulfite
Potassium metabisulphite
Potassium pentaoxodisulfate
Potassium pyrosulfite

External IDs

E-224
INS NO.224
INS-224

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Pharmacology

Indication: Not Available
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Pharmacodynamics: Not Available
Mechanism of action: Not Available
Absorption: Not Available
Volume of distribution: Not Available
Protein binding: Not Available
Metabolism: Not Available
Route of elimination: Not Available
Half-life: Not Available
Clearance: Not Available
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Toxicity: Not Available
Pathways: Not Available
Pharmacogenomic Effects/ADRs: Not Available

Interactions

Drug Interactions: This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions: Not Available

Products

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Mixture Products

Name	Ingredients	Dosage	Route	Labeller	Marketing Start	Marketing End	Region	Image
PROCALAMINE INJECTION	Potassium metabisulfite (<0.05 g/100 ml) + Alanine (0.21 g/100ml) + Arginine (0.29 g/100ml) + Calcium acetate (0.026 g/100ml) + Cysteine (<0.014 g/100 ml) + Glycerin (3 g/100ml) + Glycine (0.42 g/100ml) + Histidine (0.085 g/100ml) + Isoleucine (0.21 g/100ml) + Leucine (0.27 g/100ml) + Lysine acetate (0.22 g/100ml) + Magnesium acetate (0.054 g/100ml) + Methionine (0.16 g/100ml) + Phenylalanine (0.17 g/100ml) + Phosphoric acid (0.041 g/100ml) + Potassium chloride (0.15 g/100ml) + Proline (0.34 g/100ml) + Serine (0.18 g/100ml) + Sodium acetate (0.2 g/100ml) + Sodium chloride (0.12 g/100ml) + Threonine (0.12 g/100ml) + Tryptophan (0.046 g/100ml) + Valine (0.2 g/100ml)	Injection	Intravenous	B. BRAUN SINGAPORE PTE LTD	1995-06-29	Not applicable
PROCALAMINE SISE 1000 ML(SETSIZ)	Potassium metabisulfite (0.05 g/100ml) + Alanine (0.21 g/100ml) + Arginine (0.29 g/100ml) + Calcium acetate monohydrate (0.026 g/100ml) + Cysteine hydrochloride (0.02 g/100ml) + Glycerin (3 g/100ml) + Glycine (0.42 g/100ml) + Histidine (0.085 g/100ml) + Isoleucine (0.21 g/100ml) + Leucine (0.27 g/100ml) + Lysine (0.22 g/100ml) + Magnesium acetate tetrahydrate (0.054 g/100ml) + Methionine (0.16 g/100ml) + Phenylalanine (0.17 g/100ml) + Phosphoric acid (0.041 g/100ml) + Potassium chloride (0.149 g/100ml) + Proline (0.34 g/100ml) + Serine (0.18 g/100ml) + Sodium acetate trihydrate (0.204 g/100ml) + Sodium chloride (0.117 g/100ml) + Threonine (0.12 g/100ml) + Tryptophan (0.046 g/100ml) + Valine (0.2 g/100ml)	Solution	Parenteral	ECZACIBAŞI-BAXTER HASTANE ÜRÜNLERİ SAN.VE TİC. A.Ş.	1990-01-16	2017-11-02

Unapproved/Other Products

Name	Ingredients	Dosage	Route	Labeller	Marketing Start	Marketing End
PROCALAMINE SISE 1000 ML(SETLI)	Potassium metabisulfite (0.05 g/100ml) + Alanine (0.21 g/100ml) + Arginine (0.29 g/100ml) + Calcium acetate monohydrate (0.026 g/100ml) + Cysteine hydrochloride (0.02 g/100ml) + Glycerin (3 g/100ml) + Glycine (0.42 g/100ml) + Histidine (0.085 g/100ml) + Isoleucine (0.21 g/100ml) + Leucine (0.27 g/100ml) + Lysine (0.22 g/100ml) + Magnesium acetate tetrahydrate (0.054 g/100ml) + Methionine (0.16 g/100ml) + Phenylalanine (0.17 g/100ml) + Phosphoric acid (0.041 g/100ml) + Potassium chloride (0.149 g/100ml) + Proline (0.34 g/100ml) + Serine (0.18 g/100ml) + Sodium acetate trihydrate (0.204 g/100ml) + Sodium chloride (0.117 g/100ml) + Threonine (0.12 g/100ml) + Tryptophan (0.046 g/100ml) + Valine (0.2 g/100ml)	Solution	Parenteral	ECZACIBAŞI-BAXTER HASTANE ÜRÜNLERİ SAN.VE TİC. A.Ş.	2013-01-29	2024-01-23
PROCALAMINE SISE 500 ML(SETLI)	Potassium metabisulfite (0.05 g/100ml) + Alanine (0.21 g/100ml) + Arginine (0.29 g/100ml) + Calcium acetate monohydrate (0.026 g/100ml) + Cysteine hydrochloride (0.02 g/100ml) + Glycerin (3 g/100ml) + Glycine (0.42 g/100ml) + Histidine (0.085 g/100ml) + Isoleucine (0.21 g/100ml) + Leucine (0.27 g/100ml) + Lysine (0.22 g/100ml) + Magnesium acetate tetrahydrate (0.054 g/100ml) + Methionine (0.16 g/100ml) + Phenylalanine (0.17 g/100ml) + Phosphoric acid (0.041 g/100ml) + Potassium chloride (0.149 g/100ml) + Proline (0.34 g/100ml) + Serine (0.18 g/100ml) + Sodium acetate trihydrate (0.204 g/100ml) + Sodium chloride (0.117 g/100ml) + Threonine (0.12 g/100ml) + Tryptophan (0.046 g/100ml) + Valine (0.2 g/100ml)	Solution	Parenteral	ECZACIBAŞI-BAXTER HASTANE ÜRÜNLERİ SAN.VE TİC. A.Ş.	2013-01-29	2024-01-23
PROCALAMINE SISE 500 ML(SETSIZ)	Potassium metabisulfite (0.05 g/100ml) + Alanine (0.21 g/100ml) + Arginine (0.29 g/100ml) + Calcium acetate monohydrate (0.026 g/100ml) + Cysteine hydrochloride (0.02 g/100ml) + Glycerin (3 g/100ml) + Glycine (0.42 g/100ml) + Histidine (0.085 g/100ml) + Isoleucine (0.21 g/100ml) + Leucine (0.27 g/100ml) + Lysine (0.22 g/100ml) + Magnesium acetate tetrahydrate (0.054 g/100ml) + Methionine (0.16 g/100ml) + Phenylalanine (0.17 g/100ml) + Phosphoric acid (0.041 g/100ml) + Potassium chloride (0.149 g/100ml) + Proline (0.34 g/100ml) + Serine (0.18 g/100ml) + Sodium acetate trihydrate (0.204 g/100ml) + Sodium chloride (0.117 g/100ml) + Threonine (0.12 g/100ml) + Tryptophan (0.046 g/100ml) + Valine (0.2 g/100ml)	Solution	Parenteral	ECZACIBAŞI-BAXTER HASTANE ÜRÜNLERİ SAN.VE TİC. A.Ş.	2013-01-29	2024-01-23

Chemical Identifiers

UNII: 65OE787Q7W
CAS number: 16731-55-8
InChI Key: RWPGFSMJFRPDDP-UHFFFAOYSA-L
InChI: InChI=1S/2K.H2O5S2/c;;1-6(2)7(3,4)5/h;;(H,1,2)(H,3,4,5)/q2*+1;/p-2
IUPAC Name: dipotassium sulfinatosulfonate
SMILES: [K+].[K+].[O-]S(=O)S([O-])(=O)=O

References

General References

Not Available

External Links

ChemSpider: 26061
RxNav: 1362899
ChEMBL: CHEMBL2106901
Wikipedia: Potassium_metabisulfite

Clinical Trials

Clinical Trials

Phase	Status	Purpose	Conditions	Count

Pharmacoeconomics

Manufacturers

Not Available

Packagers

Not Available

Dosage Forms

Form	Route	Strength
Injection	Intravenous	0.21 g/100ml
Solution	Parenteral

Prices

Not Available

Patents

Not Available

Properties

State

Not Available

Experimental Properties

Not Available

Predicted Properties

Property	Value	Source
logP	-1.6	Chemaxon
pKa (Strongest Acidic)	-2.7	Chemaxon
Physiological Charge	-2	Chemaxon
Hydrogen Acceptor Count	5	Chemaxon
Hydrogen Donor Count	0	Chemaxon
Polar Surface Area	97.33 Å²	Chemaxon
Rotatable Bond Count	1	Chemaxon
Refractivity	18.73 m³·mol^-1	Chemaxon
Polarizability	9.14 Å³	Chemaxon
Number of Rings	0	Chemaxon
Bioavailability	1	Chemaxon
Rule of Five	Yes	Chemaxon
Ghose Filter	No	Chemaxon
Veber's Rule	No	Chemaxon
MDDR-like Rule	No	Chemaxon

Predicted ADMET Features

Not Available

Spectra

Mass Spec (NIST)

Not Available

Spectra

Not Available

Chromatographic Properties

Collision Cross Sections (CCS)

Adduct	CCS Value (Å²)	Source type	Source
[M-H]-	114.64542	predicted	DeepCCS 1.0 (2019)
[M+H]+	116.954636	predicted	DeepCCS 1.0 (2019)
[M+Na]+	123.33378	predicted	DeepCCS 1.0 (2019)

Drug created at September 16, 2020 16:30 / Updated at September 16, 2020 21:10

Potassium metabisulfite

Identification

Structure for Potassium metabisulfite (DB15841)

Pharmacology

Interactions

Products

Categories

Chemical Identifiers

References

Clinical Trials

Pharmacoeconomics

Properties

Spectra

Collision Cross Sections (CCS)