NAV

Carbaryl

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Summary

Carbaryl is a medication used in shampoo to remove lice.

Generic Name
Carbaryl
DrugBank Accession Number
DB15930
Background

Not Available

Type
Small Molecule
Groups
Experimental
Structure
3D
Similar Structures
Weight
Average: 201.225
Monoisotopic: 201.078978598
Chemical Formula
C12H11NO2
Synonyms
  • Carbaril
  • Carbarilo
  • Carbarilum
  • Karbaryl
External IDs
  • 200-555-0
  • ENT-23969
  • NSC-27311
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Pharmacology

Indication

Not Available

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Associated Conditions
Indication TypeIndicationCombined Product DetailsApproval LevelAge GroupPatient CharacteristicsDose Form
Treatment ofHead lice infestation•••••••••••••••••••
Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
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DipyridamoleThe therapeutic efficacy of Carbaryl can be decreased when used in combination with Dipyridamole.
Food Interactions
Not Available

Products

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Categories

Drug Categories
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
R890C8J3N1
CAS number
63-25-2
InChI Key
CVXBEEMKQHEXEN-UHFFFAOYSA-N
InChI
InChI=1S/C12H11NO2/c1-13-12(14)15-11-8-4-6-9-5-2-3-7-10(9)11/h2-8H,1H3,(H,13,14)
IUPAC Name
naphthalen-1-yl N-methylcarbamate
SMILES
CNC(=O)OC1=C2C=CC=CC2=CC=C1

References

General References
  1. FDA Thailand: HAFIF (carbaryl) shampoo [Link]
KEGG Compound
C07491
ChemSpider
5899
BindingDB
50128572
RxNav
9724
ChEBI
3390
ChEMBL
CHEMBL46917
ZINC
ZINC000000001090
Wikipedia
Carbaryl

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
LotionTopical0.65 g
SolutionTopical0.65 g
ShampooTopical0.6 %w/v
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility0.0914 mg/mLALOGPS
logP2.45ALOGPS
logP2.46Chemaxon
logS-3.3ALOGPS
pKa (Strongest Acidic)14.77Chemaxon
Physiological Charge0Chemaxon
Hydrogen Acceptor Count1Chemaxon
Hydrogen Donor Count1Chemaxon
Polar Surface Area38.33 Å2Chemaxon
Rotatable Bond Count2Chemaxon
Refractivity57.21 m3·mol-1Chemaxon
Polarizability21.12 Å3Chemaxon
Number of Rings2Chemaxon
Bioavailability1Chemaxon
Rule of FiveYesChemaxon
Ghose FilterYesChemaxon
Veber's RuleYesChemaxon
MDDR-like RuleNoChemaxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
SpectrumSpectrum TypeSplash Key
Predicted MS/MS Spectrum - 10V, Positive (Annotated)Predicted LC-MS/MSsplash10-0a4j-9400000000-66b9b0cf2d3fe48c28ce
Predicted MS/MS Spectrum - 10V, Negative (Annotated)Predicted LC-MS/MSsplash10-0a4i-9400000000-2967e0467eeb90521a60
Predicted MS/MS Spectrum - 20V, Positive (Annotated)Predicted LC-MS/MSsplash10-0002-2900000000-17f03baccea3f7d1b5d7
Predicted MS/MS Spectrum - 20V, Negative (Annotated)Predicted LC-MS/MSsplash10-0006-1900000000-d2b9b21ed105ecb8b9e2
Predicted MS/MS Spectrum - 40V, Negative (Annotated)Predicted LC-MS/MSsplash10-0006-2900000000-05e17a30bbc8ec903f9a
Predicted MS/MS Spectrum - 40V, Positive (Annotated)Predicted LC-MS/MSsplash10-1003-9600000000-23a06db04f74922aa601
Predicted 1H NMR Spectrum1D NMRNot Applicable
Predicted 13C NMR Spectrum1D NMRNot Applicable
Chromatographic Properties
Collision Cross Sections (CCS)
AdductCCS Value (Å2)Source typeSource
[M-H]-150.3951121
predicted
DarkChem Lite v0.1.0
[M-H]-150.7878121
predicted
DarkChem Lite v0.1.0
[M-H]-138.35101
predicted
DeepCCS 1.0 (2019)
[M+H]+151.2608121
predicted
DarkChem Lite v0.1.0
[M+H]+151.2845121
predicted
DarkChem Lite v0.1.0
[M+H]+140.74658
predicted
DeepCCS 1.0 (2019)
[M+Na]+150.4973121
predicted
DarkChem Lite v0.1.0
[M+Na]+147.63121
predicted
DeepCCS 1.0 (2019)

Drug created at November 24, 2020 16:28 / Updated at May 07, 2021 21:08