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Displaying drugs 176 - 200 of 2038 in total
DrugBank ID Name Weight StructureCategoriesTherapeutic Indication
DB00710
114084-78-5
Ibandronate319.2289

C9H23NO7P2
ThumbBone Density Conservation Agents / Bone Resorption / Diphosphonates / Drugs Affecting Bone Structure and Mineralization / Drugs for Treatment of Bone Diseases / Musculo-Skeletal System / Organophosphonates / Organophosphorus Compounds / QTc-Prolonging Agents (Indeterminate Risk and Risk Modifying)For the treatment and prevention of osteoporosis in postmenopausal women.
DB00678
114798-26-4
Losartan422.911

C22H23ClN6O
ThumbAgents Acting on the Renin-Angiotensin System / Angiotensin II Antagonists, Plain / Angiotensin II Type 1 Receptor Blockers / Angiotensin Receptor Antagonists / Anti-Arrhythmia Agents / Antihypertensive Agents / Benzene Derivatives / Biphenyl Compounds / Cardiovascular Agents / Cardiovascular System / Combined Inhibitors of CYP3A4 and P-glycoprotein / Cytochrome P-450 CYP1A2 Inhibitors / Cytochrome P-450 CYP1A2 Inhibitors (weak) / Cytochrome P-450 CYP2C19 Inhibitors / Cytochrome P-450 CYP2C8 Inhibitors / Cytochrome P-450 CYP2C8 Inhibitors (moderate) / Cytochrome P-450 CYP2C8 Substrates / Cytochrome P-450 CYP2C9 Inhibitors / Cytochrome P-450 CYP2C9 Inhibitors (moderate) / Cytochrome P-450 CYP2C9 Substrates / Cytochrome P-450 CYP3A Inhibitors / Cytochrome P-450 CYP3A4 Substrates / Hypotensive Agents / Imidazoles / P-glycoprotein/ABCB1 Inhibitors / P-glycoprotein/ABCB1 Substrates / TetrazolesMay be used as a first line agent to treat uncomplicated hypertension, isolated systolic hypertension and left ventricular hypertrophy. May be used...
DB00569
114870-03-0
Fondaparinux sodium1730.097

C31H45N3Na10O49S8
ThumbAnticoagulants / Carbohydrates / Factor X / Hematologic AgentsApproved for: (1) prophylaxis of VTE for up to one month post surgery in patients undergoing orthopedic surgery of the lower limbs such as hip frac...
DB05109
114899-77-3
Trabectedin761.837

C39H43N3O11S
ThumbAlkylating Agents / Antineoplastic Agents / Antineoplastic Agents, Alkylating / Antineoplastic and Immunomodulating Agents / Cytochrome P-450 CYP2C19 Substrates / Cytochrome P-450 CYP2C9 Substrates / Cytochrome P-450 CYP2D6 Substrates / Cytochrome P-450 CYP2E1 Substrates / Cytochrome P-450 CYP3A4 Substrates / Immunosuppressive Agents / Isoquinolines / Myelosuppressive Agents / Noxae / Toxic ActionsIndicated for treatment of advanced soft tissue sarcoma in patients refractory to or unsuitable to receive anthracycline or ifosfamide chemotherapy...
DB01248
114977-28-5
Docetaxel807.8792

C43H53NO14
ThumbAntimitotic Agents / Antineoplastic Agents / Antineoplastic and Immunomodulating Agents / BCRP/ABCG2 Substrates / Cyclodecanes / Cycloparaffins / Cytochrome P-450 CYP3A Inhibitors / Cytochrome P-450 CYP3A4 Substrates / Diterpenes / Immunosuppressive Agents / Mitosis Modulators / Myelosuppressive Agents / P-glycoprotein/ABCB1 Substrates / Taxane Derivatives / Taxoids / Terpenes / Tubulin ModulatorsFor the treatment of patients with locally advanced or metastatic breast cancer after failure of prior chemotherapy. Also used as a single agent in...
DB00849
115-38-8
Methylphenobarbital246.2619

C13H14N2O3
ThumbAnticonvulsants / Barbiturates / Central Nervous System Agents / Central Nervous System Depressants / Cytochrome P-450 CYP2B6 Substrates / Cytochrome P-450 CYP2C19 Inhibitors / Cytochrome P-450 CYP2C19 Substrates / GABA Agents / GABA Modulators / Hypnotics and Sedatives / Nervous System / Neurotransmitter Agents / Psycholeptics / Pyrimidines / PyrimidinonesFor the relief of anxiety, tension, and apprehension, also used as an anticonvulsant for the treatment of epilepsy.
DB00306
115-44-6
Talbutal224.2563

C11H16N2O3
ThumbBarbiturates, Plain / Hypnotics and Sedatives / Nervous System / Psycholeptics / Pyrimidines / PyrimidinonesFor use as a sedative and hypnotic.
DB00617
115-67-3
Paramethadione157.1671

C7H11NO3
ThumbAnticonvulsants / Cytochrome P-450 CYP2C8 Substrates / Cytochrome P-450 CYP2C9 Substrates / Cytochrome P-450 CYP2E1 Substrates / Cytochrome P-450 CYP3A4 Substrates / Nervous System / Oxazolidine DerivativesUsed for the control of absence (petit mal) seizures that are refractory to treatment with other medications.
DB00906
115103-54-3
Tiagabine375.548

C20H25NO2S2
ThumbAnticonvulsants / Central Nervous System Agents / Central Nervous System Depressants / Cytochrome P-450 CYP3A4 Substrates / Fatty Acid Derivatives / GABA Agents / GABA Agonists / Membrane Transport Modulators / Nervous System / Neuroprotective Agents / Neurotransmitter Agents / Neurotransmitter Uptake Inhibitors / PiperidinesFor the treatment of partial seizures
DB00204
115256-11-6
Dofetilide441.565

C19H27N3O5S2
ThumbAmides / Amines / Anti-Arrhythmia Agents / Antiarrhythmics, Class I and III / Antiarrhythmics, Class III / Cardiac Therapy / Cardiovascular Agents / Cardiovascular System / Cytochrome P-450 CYP3A4 Substrates / Ethylamines / Highest Risk QTc-Prolonging Agents / Membrane Transport Modulators / Potassium Channel Blockers / Sulfones / Sulfur CompoundsFor the maintenance of normal sinus rhythm (delay in time to recurrence of atrial fibrillation/atrial flutter [AF/AFl]) in patients with atrial fib...
DB00839
1156-19-0
Tolazamide311.4

C14H21N3O3S
ThumbAlimentary Tract and Metabolism / Blood Glucose Lowering Agents / Blood Glucose Lowering Drugs, Excl. Insulins / Drugs Used in Diabetes / Hypoglycemia-Associated Agents / Hypoglycemic Agents / Sulfones / Sulfonylurea Compounds / Sulfonylureas / Sulfur Compounds / UreaFor use as an adjunct to diet to lower the blood glucose in patients with non-insulin dependent diabetes mellitus (Type II) whose hyperglycemia can...
DB00757
115956-12-2
Dolasetron324.38

C19H20N2O3
ThumbAlimentary Tract and Metabolism / Antiemetics / Antiemetics Antagonists / Antiemetics and Antinauseants / Autonomic Agents / Central Nervous System Agents / Cytochrome P-450 CYP2C9 Substrates / Cytochrome P-450 CYP2D6 Inhibitors / Cytochrome P-450 CYP2D6 Inhibitors (weak) / Cytochrome P-450 CYP2D6 Substrates / Cytochrome P-450 CYP3A4 Substrates / Gastrointestinal Agents / Moderate Risk QTc-Prolonging Agents / Neurotransmitter Agents / Peripheral Nervous System Agents / Serotonin (5HT3) Antagonists / Serotonin Agents / Serotonin AntagonistsFor the prevention of nausea and vomiting associated with emetogenic cancer chemotherapy, including initial and repeat courses of chemotherapy. Als...
DB00476
116539-59-4
Duloxetine297.415

C18H19NOS
ThumbAnalgesics / Antidepressive Agents / Central Nervous System Agents / Cytochrome P-450 CYP1A2 Substrates / Cytochrome P-450 CYP2D6 Inhibitors / Cytochrome P-450 CYP2D6 Inhibitors (moderate) / Cytochrome P-450 CYP2D6 Substrates / Dopamine Agents / Membrane Transport Modulators / Nervous System / Neurotransmitter Agents / Neurotransmitter Uptake Inhibitors / Peripheral Nervous System Agents / Psychoanaleptics / Psychotropic Drugs / Selective Serotonin Reuptake Inhibitors / Sensory System Agents / Serotonin Modulators / Serotonin and Noradrenaline Reuptake Inhibitors / Serotonin/Norepinephrine Reuptake Inhibitors / Sulfur Compounds / ThiophenesFor the acute and maintenance treatment of major depressive disorder (MDD), as well as acute management of generalized anxiety disorder. Also used ...
DB01125
117-37-3
Anisindione252.2647

C16H12O3
ThumbIndans / IndenesFor the prophylaxis and treatment of venous thrombosis and its extension, the treatment of atrial fibrillation with embolization, the prophylaxis a...
DB00831
117-89-5
Trifluoperazine407.496

C21H24F3N3S
ThumbAlpha1 Antagonists / Antiemetics / Antipsychotic Agents / Antipsychotic Agents (First Generation [Typical]) / Autonomic Agents / Central Nervous System Agents / Central Nervous System Depressants / Cytochrome P-450 CYP1A2 Substrates / Dopamine Agents / Dopamine Antagonists / Gastrointestinal Agents / Nervous System / Neurotransmitter Agents / P-glycoprotein/ABCB1 Inhibitors / Peripheral Nervous System Agents / Phenothiazines / Phenothiazines With Piperazine Structure / Psycholeptics / Psychotropic Drugs / Sulfur Compounds / Tranquilizing AgentsFor the treatment of anxiety disorders, depressive symptoms secondary to anxiety and agitation.
DB00271
117-96-4
Diatrizoate613.9136

C11H9I3N2O4
ThumbAcids, Carbocyclic / Alcohols / Amino Sugars / Benzene Derivatives / Benzoates / Carbohydrates / Contrast Media / Diagnostic Uses of Chemicals / Diatrizoate / Hexosamines / Iodinated Contrast Agents / Iodobenzoates / Meglumine / Sorbitol / Sugar Alcohols / Triiodobenzoic Acids / Watersoluble, Nephrotropic, High Osmolar X-Ray Contrast Media / X-Ray Contrast Media, IodinatedUsed, alone or in combination, for a wide variety of diagnostic imaging methods, including angiography, urography, cholangiography, computed tomogr...
DB01129
117976-89-3
Rabeprazole359.443

C18H21N3O3S
Thumb2-Pyridinylmethylsulfinylbenzimidazoles / Acetates / Acids, Acyclic / Alimentary Tract and Metabolism / Anti-Ulcer Agents / BCRP/ABCG2 Inhibitors / Benzimidazoles / Cytochrome P-450 CYP1A2 Inducers / Cytochrome P-450 CYP2C19 Inhibitors / Cytochrome P-450 CYP2C19 Substrates / Cytochrome P-450 CYP2C8 Inhibitors / Cytochrome P-450 CYP2C8 Inhibitors (moderate) / Cytochrome P-450 CYP2C9 Inhibitors / Cytochrome P-450 CYP2D6 Inhibitors / Cytochrome P-450 CYP2D6 Inhibitors (weak) / Cytochrome P-450 CYP3A Inhibitors / Cytochrome P-450 CYP3A4 Substrates / Drugs for Acid Related Disorders / Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord) / Enzyme Inhibitors / Fatty Acids / Fatty Acids, Volatile / Gastrointestinal Agents / Hydroxy Acids / Lipids / Proton Pump Inhibitors / Pyrazoles / Pyrazolones / Pyridines / Sulfoxides / Sulfur CompoundsFor the treatment of acid-reflux disorders (GERD), peptic ulcer disease, H. pylori eradication, and prevention of gastroinetestinal bleeds with NSA...
DB01237
118-23-0
Bromodiphenhydramine334.251

C17H20BrNO
ThumbAmines / Aminoalkyl Ethers / Antihistamines for Systemic Use / Benzene Derivatives / Benzhydryl Compounds / Ethylamines / Respiratory SystemFor management of symptoms related to hay fever and other types of allergy and used to help bring up phlegm, thin secretions, and make a cough prod...
DB01611
118-42-3
Hydroxychloroquine335.872

C18H26ClN3O
ThumbAminoquinolines / Anti-Infective Agents / Antimalarials / Antiparasitic Agents / Antiparasitic Products, Insecticides and Repellents / Antiprotozoals / Antirheumatic Agents / Chloroquine / Cytochrome P-450 CYP2D6 Inhibitors / Enzyme Inhibitors / QuinolinesFor the suppressive treatment and treatment of acute attacks of malaria due to <i>Plasmodium vivax</i>, <i>P. malariae</i>, <i>P. ovale</i>, and su...
DB00399
118072-93-8
Zoledronic acid272.0896

C5H10N2O7P2
ThumbBone Density Conservation Agents / Diphosphonates / Drugs Affecting Bone Structure and Mineralization / Drugs for Treatment of Bone Diseases / Musculo-Skeletal System / Organophosphonates / Organophosphorus CompoundsFor the treatment of hypercalcemia of malignancy. Also for the treatment of patients with multiple myeloma and patients with documented bone metast...
DB00453
1181-54-0
Clomocycline508.906

C23H25ClN2O9
ThumbAntibacterials for Systemic Use / Antiinfectives for Systemic Use / Naphthacenes / TetracyclinesFor the treatment and management of Brucellosis, mycoplasma infection, acne vulgaris, chlamydial infection;Chronic bronchitis
DB00799
118292-40-3
Tazarotene351.462

C21H21NO2S
ThumbAntipsoriatics / Antipsoriatics for Topical Use / Cytochrome P-450 CYP2C8 Substrates / Dermatologic Agents / Dermatologicals / Keratolytic Agents / Noxae / Prodrugs / Pyridines / Retinoids / Teratogens / Toxic ActionsUsed to treat psoriasis, acne and sun damaged skin (photodamage).
DB04861
118457-14-0
Nebivolol405.435

C22H25F2NO4
ThumbAdrenergic Agents / Adrenergic Agonists / Adrenergic beta-1 Receptor Agonists / Adrenergic beta-Agonists / Alcohols / Amines / Amino Alcohols / Antihypertensive Agents / Benzopyrans / Beta Blocking Agents / Beta Blocking Agents and Thiazides / Beta Blocking Agents, Selective, and Thiazides / Beta-Blockers (Beta1 Selective) / Bradycardia-Causing Agents / Cardiovascular Agents / Cardiovascular System / Cytochrome P-450 CYP2D6 Substrates / Ethanol / Ethanolamines / Hypotensive Agents / Neurotransmitter Agents / Pyrans / Vasodilator AgentsFor the treatment of essential hypertension.
DB06775
1188-38-1
Carglumic Acid190.154

C6H10N2O5
ThumbAlimentary Tract and Metabolism / Amino Acids / Amino Acids and Derivatives / Amino Acids, Acidic / Amino Acids, Dicarboxylic / Amino Acids, Peptides, and ProteinsFor the treatment of acute and chronic hyperammonaemia in patients with N-acetylglutamate synthase (NAGS) deficiency. This enzyme is an important c...
DB00452
119-04-0
Framycetin614.6437

C23H46N6O13
ThumbAminoglycosides / Anti-Bacterial Agents / Anti-Infective Agents / Antiinfectives / Carbohydrates / Glycosides / Neomycin / Ophthalmologicals / Sensory OrgansFor the treatment of bacterial blepharitis, bacterial bonjunctivitis, corneal injuries, corneal ulcers and meibomianitis. For the prophylaxis of oc...
Displaying drugs 176 - 200 of 2038 in total