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Displaying drugs 176 - 200 of 2018 in total
DrugBank ID Name Weight StructureCategoriesTherapeutic Indication
DB02300
112965-21-6
Calcipotriol412.6047

C27H40O3
ThumbAntineoplastic Agents / Antipsoriatics / Antipsoriatics for Topical Use / Cholecalciferol / Cholestanes / Cholestenes / Dermatologic Agents / Dermatologicals / Dihydroxycholecalciferols / Hydroxycholecalciferols / Lipids / Membrane Lipids / Polycyclic Compounds / Secosteroids / Steroids / Sterols / Vitamin D / Vitamin D and AnaloguesFor the treatment of moderate plaque psoriasis in adults.
DB00536
113-00-8
Guanidine59.0705

CH5N3
ThumbAmidines / Guanidines / Organic ChemicalsFor the reduction of the symptoms of muscle weakness and easy fatigability associated with the myasthenic syndrome of Eaton-Lambert. It is not indi...
DB00696
113-15-5
Ergotamine581.6615

C33H35N5O5
ThumbAdrenergic Agents / Adrenergic Agonists / Adrenergic alpha-1 Receptor Agonists / Adrenergic alpha-Agonists / Alkaloids / Alpha2 Agonists / Analgesics / Analgesics, Non-Narcotic / Antimigraine Preparations / Cardiovascular Agents / Central Nervous System Agents / Combined Inhibitors of CYP3A4 and P-glycoprotein / Cytochrome P-450 CYP1A2 Substrates / Cytochrome P-450 CYP3A Inhibitors / Cytochrome P-450 CYP3A4 Substrates / Ergot Alkaloids / Ergot Derivatives / Ergotamines / Heterocyclic Compounds / Heterocyclic Compounds with 4 or More Rings / Nervous System / Neurotransmitter Agents / Oxytocics / P-glycoprotein/ABCB1 Inhibitors / Peripheral Nervous System Agents / Reproductive Control Agents / Sensory System Agents / Serotonin 5-HT1 Receptor Agonists / Serotonin Agents / Serotonin Modulators / Serotonin Receptor Agonists / Vasoconstrictor AgentsFor use as therapy to abort or prevent vascular headache, e.g., migraine, migraine variants, or so called "histaminic cephalalgia".
DB00189
113-18-8
Ethchlorvynol144.599

C7H9ClO
ThumbAlcohols / Central Nervous System Agents / Central Nervous System Depressants / Chlorohydrins / Hypnotics and Sedatives / Nervous System / Organic Chemicals / PsycholepticsUsed for short-term hypnotic therapy in the management of insomnia for periods of up to one week in duration; however, this medication generally ha...
DB00353
113-42-8
Methylergometrine339.4314

C20H25N3O2
ThumbAlkaloids / Cytochrome P-450 CYP3A Inhibitors / Ergolines / Ergonovine / Ergot Alkaloids / Genito Urinary System and Sex Hormones / Heterocyclic Compounds / Heterocyclic Compounds with 4 or More Rings / Oxytocics / Reproductive Control Agents / UterotonicsFor the prevention and control of excessive bleeding following vaginal childbirth
DB00422
113-45-1
Methylphenidate233.3062

C14H19NO2
ThumbAcids, Carbocyclic / CYP2D6 Inhibitors (Weak) / Carboxylic Acids / Central Nervous System Agents / Central Nervous System Stimulants / Centrally Acting Sympathomimetics / Cytochrome P-450 CYP2D6 Inhibitors / Cytochrome P-450 CYP2D6 Inhibitors (weak) / Cytochrome P-450 CYP2D6 Substrates / Dopamine Agents / Dopamine Uptake Inhibitors / Heterocyclic Compounds / Heterocyclic Compounds, 1-Ring / Heterocyclic Compounds, 3-Ring / Membrane Transport Modulators / Nervous System / Neurotransmitter Agents / Neurotransmitter Uptake Inhibitors / Organic Chemicals / Phenylacetates / Piperidines / Psychoanaleptics / Psychostimulants, Agents Used for Adhd and NootropicsFor use as an integral part of a total treatment program which typically includes other remedial measures (psychological, educational, social) for ...
DB09167
113-53-1
Dosulepin295.44

C19H21NS
ThumbAdrenergic Agents / Adrenergic Uptake Inhibitors / Antidepressive Agents / Antidepressive Agents, Tricyclic / Central Nervous System Agents / Dibenzothiepins / Heterocyclic Compounds / Heterocyclic Compounds, 1-Ring / Heterocyclic Compounds, 3-Ring / Inorganic Chemicals / Membrane Transport Modulators / Nervous System / Neurotransmitter Agents / Neurotransmitter Uptake Inhibitors / Non-Selective Monoamine Reuptake Inhibitors / Organic Chemicals / Psychoanaleptics / Psychotropic Drugs / Sulfur Compounds / ThiepinsNot Annotated
DB01239
113-59-7
Chlorprothixene315.86

C18H18ClNS
ThumbAntipsychotic Agents / Antipsychotic Agents (First Generation [Typical]) / Central Nervous System Agents / Central Nervous System Depressants / Dopamine Agents / Dopamine Antagonists / Heterocyclic Compounds / Heterocyclic Compounds, 3-Ring / Inorganic Chemicals / Nervous System / Neurotransmitter Agents / Organic Chemicals / P-glycoprotein/ABCB1 Inhibitors / Psycholeptics / Psychotropic Drugs / Sulfur Compounds / Thioxanthene Derivatives / Thioxanthenes / Tranquilizing Agents / XanthenesFor treatment of psychotic disorders (e.g. schizophrenia) and of acute mania occuring as part of bipolar disorders.
DB04840
1131-64-2
Debrisoquin175.2303

C10H13N3
ThumbAdrenergic Agents / Antiadrenergic Agents, Peripherally Acting / Antihypertensive Agents / Autonomic Agents / Cardiovascular Agents / Cardiovascular System / Cytochrome P-450 CYP2D6 Substrates / Guanidine Derivatives / Heterocyclic Compounds / Heterocyclic Compounds, 2-Ring / Isoquinolines / Neurotransmitter Agents / P-glycoprotein/ABCB1 Substrates / Peripheral Nervous System Agents / SympatholyticsFor the treatment of moderate and severe hypertension, either alone or as an adjunct, and for the treatment of renal hypertension.
DB09183
1132935-63-7
Dasabuvir493.58

C26H27N3O5S
ThumbAmides / Antiinfectives for Systemic Use / Antivirals for Systemic Use / BCRP/ABCG2 Inhibitors / Cytochrome P-450 CYP2C8 Substrates / Cytochrome P-450 CYP2D6 Substrates / Cytochrome P-450 CYP3A4 Substrates / Direct Acting Antivirals / Heterocyclic Compounds / Heterocyclic Compounds, 1-Ring / Inorganic Chemicals / Organic Chemicals / Pyrimidines / Pyrimidinones / Sulfones / Sulfur CompoundsDasabuvir, in combination with ombitasvir, paritaprevir, and ritonavir (as Viekira Pak) is indicated for the treatment of patients with genotype 1 ...
DB00181
1134-47-0
Baclofen213.661

C10H12ClNO2
ThumbAcids, Acyclic / Amino Acids / Amino Acids, Peptides, and Proteins / Aminobutyrates / Butyrates / Carboxylic Acids / Central Nervous System Agents / Central Nervous System Depressants / Fatty Acids / Fatty Acids, Volatile / GABA Agents / GABA Agonists / GABA-B Receptor Agonists / Lipids / Muscle Relaxants / Muscle Relaxants, Central / Muscle Relaxants, Centrally Acting Agents / Musculo-Skeletal System / Neuromuscular Agents / Neurotransmitter Agents / Organic Chemicals / Peripheral Nervous System Agents / gamma-Aminobutyric AcidFor the alleviation of signs and symptoms of spasticity resulting from multiple sclerosis, particularly for the relief of flexor spasms and concomi...
DB00743
113662-23-0
Gadobenic acid667.73

C22H28GdN3O11
ThumbAlcohols / Amino Sugars / Carbohydrates / Contrast Media / Diagnostic Uses of Chemicals / Gadolinium / Hexosamines / Magnetic Resonance Imaging Contrast Media / Moderate Risk QTc-Prolonging Agents / Organic Chemicals / Paramagnetic Contrast Media / Sorbitol / Sugar AlcoholsGadobenate Dimeglumine is an MRI contrast agent used primarily for MR imaging of the liver. It can also be used for MRI of the heart, as well as an...
DB00758
113665-84-2
Clopidogrel321.822

C16H16ClNO2S
ThumbBlood and Blood Forming Organs / CYP2C8 Inhibitors (Strong) / Cytochrome P-450 CYP1A2 Substrates / Cytochrome P-450 CYP2B6 Inhibitors / Cytochrome P-450 CYP2B6 Inhibitors (moderate) / Cytochrome P-450 CYP2B6 Substrates / Cytochrome P-450 CYP2C19 Substrates / Cytochrome P-450 CYP2C8 Inhibitors / Cytochrome P-450 CYP2C8 Inhibitors (strong) / Cytochrome P-450 CYP2C9 Inhibitors / Cytochrome P-450 CYP2C9 Substrates / Cytochrome P-450 CYP3A4 Substrates / Fibrinolytic Agents / Hematologic Agents / Heterocyclic Compounds / Heterocyclic Compounds, 1-Ring / Heterocyclic Compounds, 2-Ring / Inorganic Chemicals / Neurotransmitter Agents / Organic Chemicals / P-glycoprotein/ABCB1 Substrates / Platelet Aggregation Inhibitors / Platelet Aggregation Inhibitors Excl. Heparin / Purinergic Agents / Purinergic Antagonists / Purinergic P2 Receptor Antagonists / Purinergic P2Y Receptor Antagonists / Pyridines / Sulfur Compounds / Thienopyridines / ThiophenesFor the reduction of atherosclerotic events (myocardial infarction, stroke, and vascular death) in patients with atherosclerosis documented by rece...
DB00633
113775-47-6
Dexmedetomidine200.2795

C13H16N2
ThumbAdrenergic Agents / Adrenergic Agonists / Adrenergic alpha-2 Receptor Agonists / Adrenergic alpha-Agonists / Alpha2 Agonists / Analgesics / Analgesics, Non-Narcotic / Azoles / Bradycardia-Causing Agents / Central Nervous System Agents / Central Nervous System Depressants / Cytochrome P-450 CYP1A2 Inhibitors / Cytochrome P-450 CYP1A2 Inhibitors (weak) / Cytochrome P-450 CYP2D6 Inhibitors / Cytochrome P-450 CYP2E1 Substrates / Heterocyclic Compounds / Heterocyclic Compounds, 1-Ring / Hypnotics and Sedatives / Hypotensive Agents / Imidazoles / Nervous System / Neurotransmitter Agents / Peripheral Nervous System Agents / Psycholeptics / Sensory System AgentsFor sedation of initially intubated and mechanically ventilated patients during treatment in an intensive care setting, also used in pain relief; a...
DB00768
113806-05-6
Olopatadine337.4122

C21H23NO3
ThumbAnalgesics / Analgesics, Non-Narcotic / Anti-Allergic Agents / Anti-Inflammatory Agents / Anti-Inflammatory Agents, Non-Steroidal / Antiallergic Agents, Excl. Corticosteroids / Antirheumatic Agents / Central Nervous System Agents / Central Nervous System Depressants / Cytochrome P-450 CYP3A4 Substrates / Decongestants and Antiallergics / Dibenzoxepins / Heterocyclic Compounds / Heterocyclic Compounds, 3-Ring / Histamine Agents / Histamine Antagonists / Histamine H1 Antagonists / Histamine H1 Antagonists, Non-Sedating / Nasal Preparations / Neurotransmitter Agents / Ophthalmologicals / Peripheral Nervous System Agents / Respiratory System / Sensory Organs / Sensory System AgentsFor the treatment of ocular itching associated with allergic conjunctivitis.
DB00369
113852-37-2
Cidofovir279.187

C8H14N3O6P
ThumbAnti-Infective Agents / Antiinfectives for Systemic Use / Antiviral Agents / Antivirals for Systemic Use / Direct Acting Antivirals / Heterocyclic Compounds / Heterocyclic Compounds, 1-Ring / Nucleosides and Nucleotides Excl. Reverse Transcriptase Inhibitors / OAT3 Substrates / Organic Chemicals / Organophosphorus Compounds / Pyrimidines / PyrimidinonesFor the treatment of CMV retinitis in patients with acquired immunodeficiency syndrome (AIDS)
DB00199
114-07-8
Erythromycin733.9268

C37H67NO13
ThumbAnti-Acne Preparations / Anti-Acne Preparations for Topical Use / Anti-Bacterial Agents / Anti-Infective Agents / Antibacterials for Systemic Use / Antiinfectives / Antiinfectives for Systemic Use / Antiinfectives for Treatment of Acne / Combined Inhibitors of CYP3A4 and P-glycoprotein / Cytochrome P-450 CYP1A2 Inhibitors / Cytochrome P-450 CYP2B6 Substrates / Cytochrome P-450 CYP3A Inhibitors / Cytochrome P-450 CYP3A4 Inhibitors (moderate) / Cytochrome P-450 CYP3A4 Substrates / Dermatologicals / Enzyme Inhibitors / Erythromycin / Gastrointestinal Agents / Gastroparesis / Lactones / Macrocyclic Compounds / Macrolide Antibiotics / Macrolides / Macrolides, Lincosamides and Streptogramins / Moderate Risk QTc-Prolonging Agents / Ophthalmologicals / Organic Chemicals / P-glycoprotein/ABCB1 Inducers / P-glycoprotein/ABCB1 Inhibitors / P-glycoprotein/ABCB1 Substrates / Polycyclic Compounds / Polyketides / Protein Synthesis Inhibitors / Sensory OrgansFor use in the treatment of infections caused by susceptible strains of microorganisms in the following diseases: respiratory tract infections (upp...
DB00914
114-86-3
Phenformin205.2596

C10H15N5
ThumbAcids, Heterocyclic / Alimentary Tract and Metabolism / Amidines / Biguanides / Blood Glucose Lowering Drugs, Excl. Insulins / Cytochrome P-450 CYP2D6 Substrates / Drugs Used in Diabetes / Guanidines / Heterocyclic Compounds / Heterocyclic Compounds, 2-Ring / Hypoglycemic Agents / Indoles / Organic ChemicalsFor the reatment of type II diabetes mellitus.
DB00710
114084-78-5
Ibandronate319.2289

C9H23NO7P2
ThumbBone Density Conservation Agents / Bone Resorption / Diphosphonates / Drugs Affecting Bone Structure and Mineralization / Drugs for Treatment of Bone Diseases / Musculo-Skeletal System / Organic Chemicals / Organophosphonates / Organophosphorus Compounds / QTc-Prolonging Agents (Indeterminate Risk and Risk Modifying)For the treatment and prevention of osteoporosis in postmenopausal women.
DB00678
114798-26-4
Losartan422.911

C22H23ClN6O
ThumbAgents Acting on the Renin-Angiotensin System / Angiotensin II Antagonists and Calcium Channel Blockers / Angiotensin II Antagonists and Diuretics / Angiotensin II Antagonists, Plain / Angiotensin II Type 1 Receptor Blockers / Angiotensin Receptor Antagonists / Anti-Arrhythmia Agents / Antihypertensive Agents / Azoles / Benzene Derivatives / Biphenyl Compounds / Cardiovascular Agents / Cardiovascular System / Combined Inhibitors of CYP3A4 and P-glycoprotein / Cytochrome P-450 CYP1A2 Inhibitors / Cytochrome P-450 CYP1A2 Inhibitors (weak) / Cytochrome P-450 CYP2C19 Inhibitors / Cytochrome P-450 CYP2C8 Inhibitors / Cytochrome P-450 CYP2C8 Inhibitors (moderate) / Cytochrome P-450 CYP2C8 Substrates / Cytochrome P-450 CYP2C9 Inhibitors / Cytochrome P-450 CYP2C9 Inhibitors (moderate) / Cytochrome P-450 CYP2C9 Substrates / Cytochrome P-450 CYP3A Inhibitors / Cytochrome P-450 CYP3A4 Substrates / Heterocyclic Compounds / Heterocyclic Compounds, 1-Ring / Hydrocarbons / Hydrocarbons, Aromatic / Hydrocarbons, Cyclic / Hypotensive Agents / Imidazoles / Organic Chemicals / P-glycoprotein/ABCB1 Inhibitors / P-glycoprotein/ABCB1 Substrates / TetrazolesMay be used as a first line agent to treat uncomplicated hypertension, isolated systolic hypertension and left ventricular hypertrophy. May be used...
DB00569
114870-03-0
Fondaparinux sodium1730.097

C31H45N3Na10O49S8
ThumbAnticoagulants / Carbohydrates / Factor X / Hematologic AgentsApproved for: (1) prophylaxis of VTE for up to one month post surgery in patients undergoing orthopedic surgery of the lower limbs such as hip frac...
DB05109
114899-77-3
Trabectedin761.837

C39H43N3O11S
ThumbAlkylating Agents / Antineoplastic Agents / Antineoplastic Agents, Alkylating / Antineoplastic and Immunomodulating Agents / Cytochrome P-450 CYP2C19 Substrates / Cytochrome P-450 CYP2C9 Substrates / Cytochrome P-450 CYP2D6 Substrates / Cytochrome P-450 CYP2E1 Substrates / Cytochrome P-450 CYP3A4 Substrates / Heterocyclic Compounds / Heterocyclic Compounds, 1-Ring / Heterocyclic Compounds, 2-Ring / Immunosuppressive Agents / Isoquinolines / Myelosuppressive Agents / Noxae / Toxic ActionsIndicated for treatment of advanced soft tissue sarcoma in patients refractory to or unsuitable to receive anthracycline or ifosfamide chemotherapy...
DB01248
114977-28-5
Docetaxel807.8792

C43H53NO14
ThumbAntimitotic Agents / Antineoplastic Agents / Antineoplastic and Immunomodulating Agents / BCRP/ABCG2 Substrates / Cyclodecanes / Cycloparaffins / Cytochrome P-450 CYP3A Inhibitors / Cytochrome P-450 CYP3A4 Substrates / Diterpenes / Hydrocarbons / Hydrocarbons, Alicyclic / Hydrocarbons, Cyclic / Immunosuppressive Agents / Macrocyclic Compounds / Mitosis Modulators / Myelosuppressive Agents / Organic Chemicals / P-glycoprotein/ABCB1 Substrates / Polycyclic Compounds / Taxane Derivatives / Taxoids / Terpenes / Tubulin ModulatorsFor the treatment of patients with locally advanced or metastatic breast cancer after failure of prior chemotherapy. Also used as a single agent in...
DB00849
115-38-8
Methylphenobarbital246.2619

C13H14N2O3
ThumbAnticonvulsants / Barbiturates / Barbiturates and Derivatives / Central Nervous System Agents / Central Nervous System Depressants / Cytochrome P-450 CYP2B6 Substrates / Cytochrome P-450 CYP2C19 Inhibitors / Cytochrome P-450 CYP2C19 Substrates / GABA Agents / GABA Modulators / Heterocyclic Compounds / Heterocyclic Compounds, 1-Ring / Hypnotics and Sedatives / Nervous System / Neurotransmitter Agents / Pyrimidines / PyrimidinonesFor the relief of anxiety, tension, and apprehension, also used as an anticonvulsant for the treatment of epilepsy.
DB00306
115-44-6
Talbutal224.2563

C11H16N2O3
ThumbBarbiturates, Plain / Heterocyclic Compounds / Heterocyclic Compounds, 1-Ring / Hypnotics and Sedatives / Nervous System / Psycholeptics / Pyrimidines / PyrimidinonesFor use as a sedative and hypnotic.
Displaying drugs 176 - 200 of 2018 in total