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Displaying drugs 101 - 125 of 2019 in total
DrugBank ID Name Weight StructureCategoriesTherapeutic Indication
DB00337
137071-32-0
Pimecrolimus810.46

C43H68ClNO11
ThumbAgents for Dermatitis, Excluding Corticosteroids / Analgesics / Analgesics, Non-Narcotic / Anti-Inflammatory Agents / Anti-Inflammatory Agents, Non-Steroidal / Antirheumatic Agents / Calcineurin Inhibitors / Central Nervous System Agents / Cytochrome P-450 CYP3A4 Substrates / Dermatologic Agents / Dermatologicals / Enzyme Inhibitors / Immunologic Factors / Immunosuppressive Agents / Lactones / Macrocyclic Compounds / Macrolides / Organic Chemicals / Peptidylprolyl Isomerase, antagonists & inhibitors / Peripheral Nervous System Agents / Polycyclic Compounds / Polyketides / Sensory System AgentsFor treatment of mild to moderate atopic dermatitis.
DB01248
114977-28-5
Docetaxel807.8792

C43H53NO14
ThumbAntimitotic Agents / Antineoplastic Agents / Antineoplastic and Immunomodulating Agents / BCRP/ABCG2 Substrates / Cyclodecanes / Cycloparaffins / Cytochrome P-450 CYP3A Inhibitors / Cytochrome P-450 CYP3A4 Substrates / Diterpenes / Hydrocarbons / Hydrocarbons, Alicyclic / Hydrocarbons, Cyclic / Immunosuppressive Agents / Macrocyclic Compounds / Mitosis Modulators / Myelosuppressive Agents / Organic Chemicals / P-glycoprotein/ABCB1 Substrates / Polycyclic Compounds / Taxane Derivatives / Taxoids / Terpenes / Tubulin ModulatorsFor the treatment of patients with locally advanced or metastatic breast cancer after failure of prior chemotherapy. Also used as a single agent in...
DB09134
87771-40-2
Ioversol807.115

C18H24I3N3O9
ThumbAcids, Carbocyclic / Benzene Derivatives / Benzoates / Carboxylic Acids / Contrast Media / Diagnostic Uses of Chemicals / Hydrocarbons / Hydrocarbons, Aromatic / Hydrocarbons, Cyclic / Iodinated Contrast Agents / Iodobenzoates / Organic Chemicals / Watersoluble, Nephrotropic, Low Osmolar X-Ray Contrast Media / X-Ray Contrast Media, IodinatedOptiray 350 is indicated in adults for peripheral and coronary arteriography and left ventriculography. Optiray 350 is also indicated for contrast ...
DB00511
1111-39-3
Acetyldigitoxin806.9757

C43H66O14
ThumbAnti-Arrhythmia Agents / Carbohydrates / Cardanolides / Cardenolides / Cardiac Glycosides / Cardiac Therapy / Cardiotonic Agents / Cardiovascular Agents / Cardiovascular System / Digitalis Glycosides / Digitoxin / Enzyme Inhibitors / Glycosides / Polycyclic Compounds / Protective Agents / SteroidsUsed for fast digitalization in congestive heart failure.
DB00864
104987-11-3
Tacrolimus804.0182

C44H69NO12
ThumbAgents for Dermatitis, Excluding Corticosteroids / Antineoplastic and Immunomodulating Agents / Calcineurin Inhibitors / Combined Inhibitors of CYP3A4 and P-glycoprotein / Cytochrome P-450 CYP3A Inhibitors / Cytochrome P-450 CYP3A4 Substrates / Dermatologicals / Enzyme Inhibitors / Hyperglycemia-Associated Agents / Immunologic Factors / Immunosuppressive Agents / Lactones / Macrocyclic Compounds / Macrolides / Myelosuppressive Agents / Organic Chemicals / P-glycoprotein/ABCB1 Inducers / P-glycoprotein/ABCB1 Inhibitors / P-glycoprotein/ABCB1 Substrates / Polycyclic Compounds / PolyketidesFor use after allogenic organ transplant to reduce the activity of the patient's immune system and so the risk of organ rejection. It was first app...
DB09135
107793-72-6
Ioxilan791.116

C18H24I3N3O8
ThumbAcids, Carbocyclic / Benzene Derivatives / Benzoates / Carboxylic Acids / Contrast Media / Diagnostic Uses of Chemicals / Hydrocarbons / Hydrocarbons, Aromatic / Hydrocarbons, Cyclic / Iodinated Contrast Agents / Iodobenzoates / Organic Chemicals / Triiodobenzoic Acids / Watersoluble, Nephrotropic, Low Osmolar X-Ray Contrast Media / X-Ray Contrast Media, IodinatedWhen administered intra-arterially, Ioxilan is indicated for the following diagnostic tests: cerebral arteriography (300 mgI/mL), coronary arteri...
DB09156
73334-07-3
Iopromide791.1119

C18H24I3N3O8
ThumbAcids, Carbocyclic / Benzene Derivatives / Benzoates / Carboxylic Acids / Contrast Media / Diagnostic Uses of Chemicals / Hydrocarbons / Hydrocarbons, Aromatic / Hydrocarbons, Cyclic / Iodinated Contrast Agents / Iodobenzoates / Organic Chemicals / Triiodobenzoic Acids / Watersoluble, Nephrotropic, Low Osmolar X-Ray Contrast Media / X-Ray Contrast Media, IodinatedIopromide, as the product Iovist, is indicated for use as an X-ray contrast agent in the following procedures: Intra-arterial digital subtraction ...
DB01578
31112-62-6
Metrizamide789.1

C18H22I3N3O8
ThumbAcids, Carbocyclic / Aminoglycosides / Benzene Derivatives / Benzoates / Carbohydrates / Carboxylic Acids / Contrast Media / Diagnostic Uses of Chemicals / Glycosides / Hydrocarbons / Hydrocarbons, Aromatic / Hydrocarbons, Cyclic / Iodobenzoates / Organic Chemicals / Triiodobenzoic Acids / Watersoluble, Nephrotropic, Low Osmolar X-Ray Contrast Media / X-Ray Contrast Media, IodinatedMetrizamide is used for lumbar, thoracic, cervical, and total columnar myelography to determine the presence of abnormalities in the spinal column,...
DB01220
80621-81-4
Rifaximin785.8785

C43H51N3O11
ThumbAlimentary Tract and Metabolism / Amides / Anti-Bacterial Agents / Anti-Infective Agents / Antibiotics for Topical Use / Antidiarrheals, Intestinal Antiinflammatory/antiinfective Agents / Cytochrome P-450 CYP3A Inducers / Dermatologicals / Enzyme Inhibitors / Gastrointestinal Agents / Heterocyclic Compounds / Heterocyclic Compounds with 4 or More Rings / Heterocyclic Compounds, 1-Ring / Intestinal Antiinfectives / Lactams / Lactams, Macrocyclic / Macrocyclic Compounds / Nucleic Acid Synthesis Inhibitors / Organic Chemicals / Polycyclic CompoundsRifaximin has multiple indications by the FDA: for the treatment of patients (≥12 years of age) with traveller's diarrhea caused by noninvasive str...
DB03147
146-14-5
Flavin adenine dinucleotide785.5497

C27H33N9O15P2
ThumbAdenine Nucleotides / Biological Factors / Carbohydrates / Coenzymes / Enzymes and Coenzymes / Flavins / Glycosides / Heterocyclic Compounds / Heterocyclic Compounds, 2-Ring / Heterocyclic Compounds, 3-Ring / Nucleic Acids, Nucleotides, and Nucleosides / Nucleotides / Pigments, Biological / Pteridines / Purine Nucleotides / Purines / Riboflavin / RibonucleotidesUsed to treat eye diseases caused by vitamin B2 deficiency, such as keratitis and blepharitis.
DB00390
20830-75-5
Digoxin780.9385

C41H64O14
ThumbAnti-Arrhythmia Agents / Bradycardia-Causing Agents / Carbohydrates / Cardanolides / Cardenolides / Cardiac Glycosides / Cardiac Therapy / Cardiotonic Agents / Cardiovascular Agents / Cardiovascular System / Cytochrome P-450 CYP3A4 Substrates / Digitalis Glycosides / Enzyme Inhibitors / Glycosides / OATP1B1/SLCO1B1 Substrates / P-glycoprotein/ABCB1 Inducers / P-glycoprotein/ABCB1 Inhibitors / P-glycoprotein/ABCB1 Substrates / Polycyclic Compounds / Protective Agents / SteroidsFor the treatment and management of congestive cardiac insufficiency, arrhythmias and heart failure.
DB00361
71486-22-1
Vinorelbine778.9323

C45H54N4O8
ThumbAlkaloids / Antineoplastic Agents / Antineoplastic Agents, Phytogenic / Antineoplastic and Immunomodulating Agents / CYP2D6 Inhibitors (Weak) / Combined Inhibitors of CYP3A4 and P-glycoprotein / Cytochrome P-450 CYP2D6 Inhibitors / Cytochrome P-450 CYP2D6 Inhibitors (weak) / Cytochrome P-450 CYP2D6 Substrates / Cytochrome P-450 CYP3A Inhibitors / Cytochrome P-450 CYP3A4 Substrates / Heterocyclic Compounds / Heterocyclic Compounds, 2-Ring / Immunosuppressive Agents / Indole Alkaloids / Indoles / Myelosuppressive Agents / P-glycoprotein/ABCB1 Inhibitors / Radiation-Sensitizing Agents / Secologanin Tryptamine Alkaloids / Vinca Alkaloids / Vinca Alkaloids and AnaloguesFor the treatment of non-small-cell lung carcinoma.
DB08947
60166-93-0
Iopamidol777.0853

C17H22I3N3O8
ThumbAcids, Carbocyclic / Benzene Derivatives / Benzoates / Carboxylic Acids / Contrast Media / Diagnostic Uses of Chemicals / Hydrocarbons / Hydrocarbons, Aromatic / Hydrocarbons, Cyclic / Iodinated Contrast Agents / Iodobenzoates / Organic Chemicals / Triiodobenzoic Acids / Watersoluble, Nephrotropic, Low Osmolar X-Ray Contrast Media / X-Ray Contrast Media, Iodinated
DB00451
51-48-9
Levothyroxine776.87

C15H11I4NO4
ThumbAmino Acids / Amino Acids, Aromatic / Amino Acids, Cyclic / Amino Acids, Peptides, and Proteins / Cytochrome P-450 CYP2C8 Inhibitors / Cytochrome P-450 CYP3A4 Substrates / Hormones / Hormones, Hormone Substitutes, and Hormone Antagonists / P-glycoprotein/ABCB1 Inducers / Systemic Hormonal Preparations, Excl. Sex Hormones and Insulins / Thyroid Hormones / Thyroid Preparations / Thyroid Products / Thyroid TherapyFor use alone or in combination with antithyroid agents to treat hypothyroidism, goiter, chronic lymphocytic thyroiditis, myxedema coma, and stupor.
DB00509
51-49-0
Dextrothyroxine776.87

C15H11I4NO4
ThumbAmino Acids / Amino Acids, Aromatic / Amino Acids, Cyclic / Amino Acids, Peptides, and Proteins / Cardiovascular System / Hormones / Hormones, Hormone Substitutes, and Hormone Antagonists / Lipid Modifying Agents / Lipid Modifying Agents, Plain / Thyroid HormonesUsed to lower high cholesterol levels in the blood.
DB08818
9004-61-9
Hyaluronic acid776.6486

C28H44N2O23
ThumbAdjuvants, Immunologic / Carbohydrates / Cicatrizants / Dermatologicals / Glycosaminoglycans / Immunologic Factors / Lubricants / Musculo-Skeletal System / Nasal Preparations / Ophthalmologicals / Polysaccharides / Preparations for Treatment of Wounds and Ulcers / Protective Agents / Respiratory System / Sensory Organs / Surgical Aids / Viscoelastic Substances / ViscosupplementsUsed to treat knee pain in patients with joint inflammation (osteoarthritis). It is usually used in patients who have not responded to other treatm...
DB06441
163706-06-7
Cangrelor776.35

C17H25Cl2F3N5O12P3S2
ThumbAdenine Nucleotides / Blood and Blood Forming Organs / Carbohydrates / Fibrinolytic Agents / Glycosides / Hematologic Agents / Heterocyclic Compounds / Heterocyclic Compounds, 2-Ring / Neurotransmitter Agents / Nucleic Acids, Nucleotides, and Nucleosides / Nucleotides / Platelet Aggregation Inhibitors / Platelet Aggregation Inhibitors Excl. Heparin / Purine Nucleotides / Purinergic Agents / Purinergic Antagonists / Purinergic P2 Receptor Antagonists / Purinergic P2Y Receptor Antagonists / Purines / RibonucleotidesFor use as an adjunct to percutaneous coronary intervention (PCI) for reducing the risk of periprocedural myocardial infarction (MI), repeat corona...
DB09065
1004316-88-4
Cobicistat776.03

C40H53N7O5S2
ThumbAcids, Acyclic / Anti-HIV Agents / Anti-Infective Agents / Anti-Retroviral Agents / Antiinfectives for Systemic Use / Antiviral Agents / Antivirals for Systemic Use / Azoles / BCRP/ABCG2 Inhibitors / Carbamates / Carboxylic Acids / Chemically-Induced Disorders / Cytochrome P-450 CYP2D6 Inhibitors / Cytochrome P-450 CYP2D6 Inhibitors (moderate) / Cytochrome P-450 CYP3A Inhibitors / Cytochrome P-450 CYP3A4 Inhibitors (strong) / Cytochrome P-450 Enzyme Inhibitors / Direct Acting Antivirals / Enzyme Inhibitors / Heterocyclic Compounds / Heterocyclic Compounds, 1-Ring / Inorganic Chemicals / Organic Chemicals / P-glycoprotein/ABCB1 Inhibitors / Sulfur Compounds / ThiazolesCobicistat is a CYP3A inhibitor indicated to increase systemic exposure of atazanavir or darunavir (once daily dosing regimen) in combination with ...
DB09161
109581-73-9
Technetium Tc-99m sestamibi775.96

C36H66N6O6Tc
ThumbCardiovascular System / Diagnostic Radiopharmaceuticals / Diagnostic Uses of Chemicals / Indicators and Reagents / Laboratory Chemicals / Nitriles / Organic Chemicals / Organometallic Compounds / Organotechnetium Compounds / P-glycoprotein/ABCB1 Substrates / Radiopharmaceuticals / Technetium (99Mtc) CompoundsTechnetium Tc 99m Sestamibi is indicated for: 1) detecting coronary artery disease by localizing myocardial ischemia (reversible defects) and infar...
DB09374
3599-32-4
Indocyanine green774.97

C43H47N2NaO6S2
ThumbColoring Agents / Heterocyclic Compounds / Heterocyclic Compounds, 2-Ring / IndolesNot Annotated
DB00183
5534-95-2
Pentagastrin767.9

C37H49N7O9S
ThumbAmino Acids, Peptides, and Proteins / Diagnostic Agents / Gastrins / Gastrointestinal Hormones / Hormones / Hormones, Hormone Substitutes, and Hormone Antagonists / Nerve Tissue Proteins / Neuropeptides / Oligopeptides / Peptide Hormones / Peptides / Proteins / Tests for Gastric SecretionUsed as a diagnostic aid for evaluation of gastric acid secretory function
DB11575
1350514-68-9
Grazoprevir766.903

C38H50N6O9S
ThumbHeterocyclic Compounds / Heterocyclic Compounds, 2-Ring / NS3/4A Protease Inhibitors / OATP1B1/SLCO1B1 Substrates / P-glycoprotein/ABCB1 SubstratesGrazoprevir is indicated in combination with elbasvir (as the fixed dose combination product Zepatier) with or without ribavirin for treatment of c...
DB09297
1216941-48-8
Paritaprevir765.89

C40H43N7O7S
ThumbAntiinfectives for Systemic Use / Antiviral Agents / Antivirals for Systemic Use / Cytochrome P-450 CYP3A4 Substrates / Direct Acting Antivirals / NS3/4A Protease Inhibitors / Polycyclic CompoundsWhen used within the fixed dose combination product of paritaprevir/ombitasvir/ritonavir (Technivie), paritaprevir is indicated in combination with...
DB01396
71-63-6
Digitoxin764.9391

C41H64O13
ThumbAnti-Arrhythmia Agents / Carbohydrates / Cardanolides / Cardenolides / Cardiac Glycosides / Cardiac Therapy / Cardiotonic Agents / Cardiovascular Agents / Cardiovascular System / Cytochrome P-450 CYP3A4 Substrates / Digitalis Glycosides / Enzyme Inhibitors / Glycosides / P-glycoprotein/ABCB1 Substrates / Polycyclic Compounds / Protective Agents / SteroidsFor the treatment and management of congestive cardiac insufficiency, arrhythmias and heart failure.
DB05109
114899-77-3
Trabectedin761.837

C39H43N3O11S
ThumbAlkylating Agents / Antineoplastic Agents / Antineoplastic Agents, Alkylating / Antineoplastic and Immunomodulating Agents / Cytochrome P-450 CYP2C19 Substrates / Cytochrome P-450 CYP2C9 Substrates / Cytochrome P-450 CYP2D6 Substrates / Cytochrome P-450 CYP2E1 Substrates / Cytochrome P-450 CYP3A4 Substrates / Heterocyclic Compounds / Heterocyclic Compounds, 1-Ring / Heterocyclic Compounds, 2-Ring / Immunosuppressive Agents / Isoquinolines / Myelosuppressive Agents / Noxae / Toxic ActionsIndicated for treatment of advanced soft tissue sarcoma in patients refractory to or unsuitable to receive anthracycline or ifosfamide chemotherapy...
Displaying drugs 101 - 125 of 2019 in total