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Displaying drugs 1426 - 1450 of 2013 in total
DrugBank ID Name Weight StructureCategoriesTherapeutic Indication
DB01261
486460-32-6
Sitagliptin407.3136

C16H15F6N5O
ThumbAlimentary Tract and Metabolism / Azoles / Blood Glucose Lowering Agents / Blood Glucose Lowering Drugs, Excl. Insulins / Cytochrome P-450 CYP2C8 Substrates / Cytochrome P-450 CYP3A4 Substrates / DPP-IV Inhibitors / Dipeptidyl Peptidase 4 (dpp-4) Inhibitors / Dipeptidyl-Peptidase IV Inhibitors / Drugs Used in Diabetes / Enzyme Inhibitors / Heterocyclic Compounds / Heterocyclic Compounds, 1-Ring / Hormones / Hormones, Hormone Substitutes, and Hormone Antagonists / Hypoglycemic Agents / Incretins / P-glycoprotein/ABCB1 Substrates / Protease Inhibitors / Pyrazines / TriazolesFor use as an adjunct to diet and exercise to improve glycemic control in patients with type 2 diabetes mellitus. Also for use in patients with typ...
DB00831
117-89-5
Trifluoperazine407.496

C21H24F3N3S
ThumbAlpha1 Antagonists / Antiemetics / Antipsychotic Agents / Antipsychotic Agents (First Generation [Typical]) / Autonomic Agents / Central Nervous System Agents / Central Nervous System Depressants / Cytochrome P-450 CYP1A2 Substrates / Dopamine Agents / Dopamine Antagonists / Gastrointestinal Agents / Heterocyclic Compounds / Heterocyclic Compounds, 3-Ring / Inorganic Chemicals / Nervous System / Neurotransmitter Agents / Organic Chemicals / P-glycoprotein/ABCB1 Inhibitors / Peripheral Nervous System Agents / Phenothiazines / Phenothiazines With Piperazine Structure / Psycholeptics / Psychotropic Drugs / Sulfur Compounds / Tranquilizing AgentsFor the treatment of anxiety disorders, depressive symptoms secondary to anxiety and agitation.
DB09031
58066-85-6
Miltefosine407.576

C21H46NO4P
ThumbAlcohols / Amines / Amino Alcohols / Ammonium Compounds / Anti-Infective Agents / Antifungal Agents / Antineoplastic Agents / Antineoplastic and Immunomodulating Agents / Antiparasitic Agents / Antiprotozoals / Choline / Ethanol / Ethanolamines / Inorganic Chemicals / Nitrogen Compounds / Onium Compounds / Organic Chemicals / Quaternary Ammonium Compounds / Trimethyl Ammonium CompoundsFor the treatment of mucosal (caused by Leishmania braziliensis), cutaneous (caused by L. braziliensis, L. guyanensis, and L. panamensis), and visc...
DB00706
106133-20-4
Tamsulosin408.512

C20H28N2O5S
ThumbAdrenergic Agents / Adrenergic Antagonists / Adrenergic alpha-1 Receptor Antagonists / Adrenergic alpha-Antagonists / Alpha-Adrenoreceptor Antagonists / Alpha1 Antagonists / Amides / Cytochrome P-450 CYP2D6 Substrates / Cytochrome P-450 CYP3A4 Substrates / Drugs Used in Benign Prostatic Hypertrophy / Genito Urinary System and Sex Hormones / Hypotensive Agents / Inorganic Chemicals / Neurotransmitter Agents / Organic Chemicals / Sulfones / Sulfur Compounds / Urological Agents / UrologicalsUsed in the treatment of signs and symptoms of benign prostatic hyperplasia (reduction in urinary obstruction and relief of associated manifestatio...
DB02659
81-25-4
Cholic Acid408.5714

C24H40O5
ThumbAlimentary Tract and Metabolism / BSEP/ABCB11 Inhibitors / Bile Acid Preparations / Bile Acids and Salts / Bile Therapy / Bile and Liver Therapy / Cholanes / Cholic Acids / OATP1B1/SLCO1B1 Substrates / P-glycoprotein/ABCB1 Inducers / Polycyclic Compounds / SteroidsOral cholic acid is indicated for: treatment of bile acid synthesis disorders due to single enzyme defects; and as adjunctive treatment of peroxiso...
DB06292
461432-26-8
Dapagliflozin408.873

C21H25ClO6
ThumbAlimentary Tract and Metabolism / Benzene Derivatives / Blood Glucose Lowering Agents / Blood Glucose Lowering Drugs, Excl. Insulins / Carbohydrates / Cytochrome P-450 CYP1A2 Substrates / Cytochrome P-450 CYP2A6 Substrates / Cytochrome P-450 CYP2C9 Substrates / Cytochrome P-450 CYP2D6 Substrates / Cytochrome P-450 CYP3A4 Substrates / Drugs Used in Diabetes / Glycosides / Hydrocarbons / Hydrocarbons, Aromatic / Hydrocarbons, Cyclic / Hypotensive Agents / Organic Chemicals / P-glycoprotein/ABCB1 Substrates / Sodium-Glucose Transport Proteins, antagonists & inhibitorsDapagliflozin is indicated for adjunct management of glycemic control in patients with type 2 diabetes mellitus, in combination with diet and exerc...
DB00381
88150-42-9
Amlodipine408.876

C20H25ClN2O5
ThumbACE Inhibitors and Calcium Channel Blockers / Agents Acting on the Renin-Angiotensin System / Angiotensin II Antagonists and Calcium Channel Blockers / Antianginal Agents / Antihypertensive Agents / CYP2D6 Inhibitors (Weak) / CYP3A4 Inhibitors (Weak) / Calcium Channel Blockers / Calcium Channel Blockers (Dihydropyridine) / Calcium Channel Blockers and Diuretics / Cardiovascular Agents / Cardiovascular System / Combined Inhibitors of CYP3A4 and P-glycoprotein / Cytochrome P-450 CYP1A2 Inhibitors / Cytochrome P-450 CYP1A2 Inhibitors (weak) / Cytochrome P-450 CYP2A6 Inhibitors / Cytochrome P-450 CYP2B6 Inhibitors / Cytochrome P-450 CYP2C8 Inhibitors / Cytochrome P-450 CYP2C9 Inhibitors / Cytochrome P-450 CYP2D6 Inhibitors / Cytochrome P-450 CYP2D6 Inhibitors (weak) / Cytochrome P-450 CYP3A Inhibitors / Cytochrome P-450 CYP3A4 Inhibitors (weak) / Cytochrome P-450 CYP3A4 Substrates / Dihydropyridine Derivatives / Dihydropyridines / Heterocyclic Compounds / Heterocyclic Compounds, 1-Ring / Hypotensive Agents / Lipid Modifying Agents / Membrane Transport Modulators / P-glycoprotein/ABCB1 Inhibitors / Pyridines / Renin-Inhibitors / Selective Calcium Channel Blockers With Mainly Vascular Effects / Vasodilator AgentsFor the treatment of hypertension and chronic stable angina.
DB09237
103129-82-4
Levamlodipine408.88

C20H25ClN2O5
ThumbAcids, Heterocyclic / Heterocyclic Compounds / Heterocyclic Compounds, 1-Ring / Nicotinic Acids / PyridinesFor the treatment of hypertension.
DB00240
67452-97-5
Alclometasone408.916

C22H29ClO5
ThumbAdrenal Cortex Hormones / Anti-Inflammatory Agents / Corticosteroids, Dermatological Preparations / Corticosteroids, Moderately Potent (Group II) / Corticosteroids, Plain / Cytochrome P-450 CYP3A Inducers / Cytochrome P-450 CYP3A4 Substrates / Dermatologicals / Glucocorticoids / Hormones / Hormones, Hormone Substitutes, and Hormone Antagonists / Ophthalmologicals / Polycyclic Compounds / Prednisolone / Pregnadienes / Pregnadienetriols / Pregnanes / Sensory Organs / SteroidsFor the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses.
DB00973
163222-33-1
Ezetimibe409.4252

C24H21F2NO3
ThumbAnticholesteremic Agents / Antimetabolites / Azetidines / Azetines / BCRP/ABCG2 Substrates / Cardiovascular System / Cytochrome P-450 CYP3A Inhibitors / Heterocyclic Compounds / Heterocyclic Compounds, 1-Ring / Hypolipidemic Agents / Lipid Modifying Agents / Lipid Modifying Agents, Plain / Lipid Regulating Agents / Noxae / OATP1B1/SLCO1B1 Substrates / P-glycoprotein/ABCB1 Substrates / Toxic ActionsFor use as adjunctive therapy to diet for the reduction of elevated total-C, LDL-C, and Apo B in patients with primary (heterozygous familial and n...
DB01415
97519-39-6
Ceftibuten410.425

C15H14N4O6S2
ThumbAmides / Anti-Bacterial Agents / Anti-Infective Agents / Antibacterials for Systemic Use / Antiinfectives for Systemic Use / Aza Compounds / Azabicyclo Compounds / Bicyclo Compounds / Bicyclo Compounds, Heterocyclic / Bridged Compounds / Heterocyclic Compounds / Heterocyclic Compounds, 1-Ring / Heterocyclic Compounds, 2-Ring / Heterocyclic Compounds, Bridged-Ring / Hydrocarbons / Hydrocarbons, Cyclic / Inorganic Chemicals / Lactams / Organic Chemicals / Polycyclic Compounds / Sulfur Compounds / Thiazines / Third-Generation Cephalosporins / beta-LactamsUsed to treat acute bacterial exacerbations of chronic bronchitis (ABECB), acute bacterial otitis media, pharyngitis, and tonsilitis.
DB00223
2557-49-5
Diflorasone410.4515

C22H28F2O5
ThumbAdrenal Cortex Hormones / Anti-Inflammatory Agents / Corticosteroids, Dermatological Preparations / Corticosteroids, Plain / Corticosteroids, Potent (Group III) / Dermatologicals / Glucocorticoids / Hormones / Hormones, Hormone Substitutes, and Hormone Antagonists / Polycyclic Compounds / Pregnadienes / Pregnadienetriols / Pregnanes / Steroids / Steroids, FluorinatedFor relief of the inflammatory and pruritic manifestations of corticosteroid responsive dermatoses.
DB00663
2135-17-3
Flumethasone410.458

C22H28F2O5
ThumbAdrenal Cortex Hormones / Anti-Inflammatory Agents / Corticosteroids, Dermatological Preparations / Corticosteroids, Moderately Potent (Group II) / Corticosteroids, Plain / Dermatologicals / Glucocorticoids / Hormones / Hormones, Hormone Substitutes, and Hormone Antagonists / Otologicals / Polycyclic Compounds / Pregnadienes / Pregnadienetriols / Pregnanes / Sensory Organs / Steroids / Steroids, FluorinatedFor the treatment of contact dermatitis, atopic dermatitis, exczema, psoriasis, diaper rash and other skin conditions
DB00734
106266-06-2
Risperidone410.4845

C23H27FN4O2
ThumbAlpha1 Antagonists / Alpha2 Agonists / Antipsychotic Agents / Antipsychotic Agents (Second Generation [Atypical]) / CYP2D6 Inhibitors (Weak) / Central Nervous System Agents / Central Nervous System Depressants / Cytochrome P-450 CYP2D6 Inhibitors / Cytochrome P-450 CYP2D6 Inhibitors (weak) / Cytochrome P-450 CYP2D6 Substrates / Cytochrome P-450 CYP3A Inhibitors / Cytochrome P-450 CYP3A4 Substrates / Dopamine Agents / Dopamine Antagonists / Heterocyclic Compounds / Heterocyclic Compounds, 1-Ring / Hyperglycemia-Associated Agents / Nervous System / Neurotransmitter Agents / P-glycoprotein/ABCB1 Substrates / Psycholeptics / Psychotropic Drugs / Pyrimidines / Pyrimidinones / QTc-Prolonging Agents (Indeterminate Risk and Risk Modifying) / Serotonin Agents / Serotonin Antagonists / Tranquilizing AgentsFor the treatment of schizophrenia in adults and in adolescents, ages 13 to 17, and for the short-term treatment of manic or mixed episodes of bipo...
DB00838
4828-27-7
Clocortolone410.907

C22H28ClFO4
ThumbAdrenal Cortex Hormones / Anti-Inflammatory Agents / Corticosteroids, Dermatological Preparations / Corticosteroids, Moderately Potent (Group II) / Corticosteroids, Plain / Dermatologicals / Glucocorticoids / Hormones / Hormones, Hormone Substitutes, and Hormone Antagonists / Polycyclic Compounds / Pregnadienediols / Pregnadienes / Pregnanes / Steroids / Steroids, FluorinatedFor short-term topical treatment of the inflammatory and pruritic manifestations of moderate to severe corticosteroid-responsive dermatoses of the ...
DB01349
145733-36-4
Tasosartan411.4591

C23H21N7O
ThumbAgents Acting on the Renin-Angiotensin System / Angiotensin II Antagonists, Plain / Angiotensin II Type 1 Receptor Blockers / Angiotensin Receptor Antagonists / Azoles / Cardiovascular System / Cytochrome P-450 CYP3A4 Substrates / Heterocyclic Compounds / Heterocyclic Compounds, 1-RingTasosartan is infrequently in the treatment of hypertension and heart failure.
DB01095
93957-54-1
Fluvastatin411.4659

C24H26FNO4
ThumbAnticholesteremic Agents / Antimetabolites / Antioxidants / CYP2D6 Inhibitors (Weak) / Cardiovascular System / Cytochrome P-450 CYP1A2 Inhibitors / Cytochrome P-450 CYP1A2 Inhibitors (weak) / Cytochrome P-450 CYP2B6 Inducers / Cytochrome P-450 CYP2C19 Inhibitors / Cytochrome P-450 CYP2C8 Inhibitors / Cytochrome P-450 CYP2C8 Substrates / Cytochrome P-450 CYP2C9 Inducers / Cytochrome P-450 CYP2C9 Inhibitors / Cytochrome P-450 CYP2C9 Inhibitors (moderate) / Cytochrome P-450 CYP2C9 Substrates / Cytochrome P-450 CYP2D6 Inhibitors / Cytochrome P-450 CYP2D6 Inhibitors (weak) / Cytochrome P-450 CYP2D6 Substrates / Cytochrome P-450 CYP3A Inducers / Cytochrome P-450 CYP3A Inhibitors / Cytochrome P-450 CYP3A4 Substrates / Enzyme Inhibitors / Fatty Acids / Fatty Acids, Unsaturated / Heterocyclic Compounds / Heterocyclic Compounds, 2-Ring / Hydroxymethylglutaryl-CoA Reductase Inhibitors / Hypolipidemic Agents / Lipid Modifying Agents / Lipid Modifying Agents, Plain / Lipid Regulating Agents / Lipids / Noxae / Toxic ActionsTo be used as an adjunct to dietary therapy to prevent cardiovascular events. May be used as secondary prevention in patients with coronary heart d...
DB09292
149709-62-6
Sacubitril411.498

C24H29NO5
ThumbAcids, Acyclic / Agents Acting on the Renin-Angiotensin System / Amino Acids / Amino Acids, Peptides, and Proteins / Angiotensin Receptor Antagonists / Azoles / Butyrates / Carboxylic Acids / Cardiovascular System / Fatty Acids / Fatty Acids, Volatile / Heterocyclic Compounds / Heterocyclic Compounds, 1-Ring / Hypotensive Agents / Lipids / Neprilysin, antagonists & inhibitors / Organic ChemicalsUsed in combination with valsartan to reduce the risk of cardiovascular events in patients with chronic heart failure (NYHA Class II-IV) and reduce...
DB01063
2751-68-0
Acetophenazine411.56

C23H29N3O2S
ThumbAntipsychotic Agents / Heterocyclic Compounds / Heterocyclic Compounds, 3-Ring / Inorganic Chemicals / Nervous System / Organic Chemicals / Phenothiazines With Piperazine Structure / Psycholeptics / Sulfur CompoundsFor the treatment of disorganized and psychotic thinking. Also used to help treat false perceptions (e.g. hallucinations or delusions.)
DB06702
286930-02-7
Fesoterodine411.5769

C26H37NO3
ThumbBenzene Derivatives / Cholinergic Agents / Cholinergic Antagonists / Cytochrome P-450 CYP2D6 Substrates / Cytochrome P-450 CYP3A4 Substrates / Drugs for Urinary Frequency and Incontinence / Genito Urinary System and Sex Hormones / Hydrocarbons / Hydrocarbons, Aromatic / Hydrocarbons, Cyclic / Muscarinic Antagonists / Neurotransmitter Agents / Organic Chemicals / P-glycoprotein/ABCB1 Substrates / Urological Agents / UrologicalsFor the treatment of overactive bladder (with symptoms of urinary frequency, urgency, or urge incontinence).
DB00639
64872-76-0
Butoconazole411.776

C19H17Cl3N2S
ThumbAnti-Infective Agents / Antifungal Agents / Antifungal Agents (Vaginal) / Azoles / Genito Urinary System and Sex Hormones / Gynecological Antiinfectives and Antiseptics / Heterocyclic Compounds / Heterocyclic Compounds, 1-Ring / Imidazole DerivativesFor the local treatment of vulvovaginal candidiasis (infections caused by Candida)
DB00332
22254-24-6
Ipratropium bromide412.361

C20H30BrNO3
ThumbAdrenergics, Inhalants / Agents to Treat Airway Disease / Alkaloids / Anti-Asthmatic Agents / Atropine Derivatives / Autonomic Agents / Aza Compounds / Azabicyclo Compounds / Belladonna Alkaloids / Bicyclo Compounds / Bicyclo Compounds, Heterocyclic / Bridged Compounds / Bronchodilator Agents / Cholinergic Agents / Cholinergic Antagonists / Cytochrome P-450 CYP2D6 Substrates / Cytochrome P-450 CYP3A4 Substrates / Drugs for Obstructive Airway Diseases / Heterocyclic Compounds / Heterocyclic Compounds, 2-Ring / Heterocyclic Compounds, Bridged-Ring / Hydrocarbons / Hydrocarbons, Cyclic / Nasal Preparations / Neurotransmitter Agents / Organic Chemicals / Peripheral Nervous System Agents / Polycyclic Compounds / Respiratory System / Respiratory System Agents / Solanaceous Alkaloids / TropanesFor maintenance treatment of bronchospasm associated with chronic obstructive pulmonary disease, including chronic bronchitis and emphysema.
DB00210
106685-40-9
Adapalene412.5201

C28H28O3
ThumbAnalgesics / Analgesics, Non-Narcotic / Anti-Acne Preparations / Anti-Acne Preparations for Topical Use / Anti-Inflammatory Agents / Anti-Inflammatory Agents, Non-Steroidal / Antirheumatic Agents / Central Nervous System Agents / Dermatologic Agents / Dermatologicals / Hydrocarbons / Hydrocarbons, Aromatic / Hydrocarbons, Cyclic / Naphthalenes / Organic Chemicals / Peripheral Nervous System Agents / Polycyclic Compounds / Polycyclic Hydrocarbons, Aromatic / Retinoic Acid Derivatives / Retinoids for Topical Use in Acne / Sensory System AgentsFor the topical treatment of comedo, papular and pustular acne (acne vulgaris) of the face, chest or back.
DB00587
128312-51-6
Cinalukast412.545

C23H28N2O3S
ThumbAzoles / Heterocyclic Compounds / Heterocyclic Compounds, 1-Ring / Inorganic Chemicals / Organic Chemicals / Sulfur CompoundsFor Protection against second- phase inflamation in exercise-induced bronchoconstriction and Asthma.
DB02300
112965-21-6
Calcipotriol412.6047

C27H40O3
ThumbAntineoplastic Agents / Antipsoriatics / Antipsoriatics for Topical Use / Cholecalciferol / Cholestanes / Cholestenes / Dermatologic Agents / Dermatologicals / Dihydroxycholecalciferols / Hydroxycholecalciferols / Lipids / Membrane Lipids / Polycyclic Compounds / Secosteroids / Steroids / Sterols / Vitamin D / Vitamin D and AnaloguesFor the treatment of moderate plaque psoriasis in adults.
Displaying drugs 1426 - 1450 of 2013 in total