Diverticulitis

Also known as: Diverticulitides / Diverticulitis NOS

DrugDrug NameDrug Description
DB00424HyoscyamineHyoscyamine is a chemical compound, a tropane alkaloid it is the levo-isomer to atropine. It is a secondary metabolite of some plants, particularly henbane (Hyoscamus niger.) Hyoscyamine is used to provide symptomatic relief to various gastrointestinal disorders including spasms, peptic ulcers, irritable bowel syndrome, pancreatitis, colic and cystitis. It has also been used to relieve some heart problems, control some of the symptoms of Parkinson's disease, as well as for control of respiratory secretions in end of life care.
DB01137LevofloxacinA synthetic fluoroquinolone (fluoroquinolones) antibacterial agent that inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
DB00454MeperidineA narcotic analgesic that can be used for the relief of most types of moderate to severe pain, including postoperative pain and the pain of labor. Prolonged use may lead to dependence of the morphine type; withdrawal symptoms appear more rapidly than with morphine and are of shorter duration.
DrugDrug NameTargetType
DB00424HyoscyamineMuscarinic acetylcholine receptor M1target
DB00424HyoscyamineMuscarinic acetylcholine receptor M2target
DB00424HyoscyamineMuscarinic acetylcholine receptor M3target
DB00424HyoscyamineMuscarinic acetylcholine receptor M4target
DB01137LevofloxacinDNA gyrase subunit Atarget
DB01137LevofloxacinDNA topoisomerase 4 subunit Atarget
DB01137LevofloxacinDNA topoisomerase 2-alphatarget
DB01137LevofloxacinCytochrome P450 1A2enzyme
DB01137LevofloxacinSolute carrier family 22 member 2transporter
DB01137LevofloxacinMultidrug resistance protein 1transporter
DB01137LevofloxacinSolute carrier family 22 member 4transporter
DB01137LevofloxacinSolute carrier family 22 member 6transporter
DB01137LevofloxacinCytochrome P450 3A4enzyme
DB01137LevofloxacinMultidrug and toxin extrusion protein 1transporter
DB01137LevofloxacinMultidrug and toxin extrusion protein 2transporter
DB00454MeperidineKappa-type opioid receptortarget
DB00454MeperidineCytochrome P450 2D6enzyme
DB00454MeperidineCytochrome P450 2B6enzyme
DB00454MeperidineGlutamate receptor ionotropic, NMDA 1target
DB00454MeperidineGlutamate receptor ionotropic, NMDA 2Btarget
DB00454MeperidineGlutamate receptor ionotropic, NMDA 2Atarget
DB00454MeperidineGlutamate receptor ionotropic, NMDA 2Ctarget
DB00454MeperidineGlutamate receptor ionotropic, NMDA 2Dtarget
DB00454MeperidineCytochrome P450 2C19enzyme
DB00454MeperidineCytochrome P450 3A4enzyme
DB00454MeperidineSerum albumincarrier
DB00454MeperidineAlpha-1-acid glycoprotein 1carrier
DB00454MeperidineMuscarinic acetylcholine receptortarget
DB00454MeperidineMu-type opioid receptortarget
DB00454MeperidineSodium-dependent dopamine transportertarget
DB00454MeperidineSodium-dependent noradrenaline transportertarget
DB00454MeperidineSodium-dependent serotonin transportertarget
DB00454MeperidineLiver carboxylesterase 1target
DB00454MeperidineCytochrome P450 1A2enzyme
DrugDrug NamePhaseStatusCount
DB00898Ethanol0Recruiting1
DB00916Metronidazole0Recruiting1
DB00994Neomycin0Recruiting1
DB09287Polyethylene glycol0Recruiting1
DB11077Polyethylene glycol 4000Recruiting1
DB00668Epinephrine2Completed1
DB00281Lidocaine2Completed1
DB00244Mesalazine2Completed1
DB01164Calcium Chloride3Completed1
DB09106Hydroxyethyl Starch3Completed1
DB04398Lactic Acid3Completed1
DB00244Mesalazine3Completed1
DB06396Mesalazine3Completed1
DB00244Mesalazine3Terminated2
DB00761Potassium chloride3Completed1
DB09153Sodium chloride3Completed1
DB00297Bupivacaine4Completed1
DB00668Epinephrine4Completed1
DB00560Tigecycline4Completed2
DB00316AcetaminophenNot AvailableCompleted1
DB00626BacitracinNot AvailableCompleted1
DB00201CaffeineNot AvailableRecruiting1
DB00668EpinephrineNot AvailableCompleted1
DB01050IbuprofenNot AvailableCompleted1
DB00281LidocaineNot AvailableCompleted1
DB00994NeomycinNot AvailableCompleted1
DB00781Polymyxin BNot AvailableCompleted1
DB09345PramocaineNot AvailableCompleted1
DB11599Starch, cornNot AvailableRecruiting1