Shock, Septic

Also known as: Septic shock / [D]Septic shock / Shock septic

DrugDrug NameDrug Description
DB00668EpinephrineA hormone and neurotransmitter used to treat allergic reactions, to restore cardiac rhythm, and to control mucosal congestion, glaucoma, and asthma.
DB01064IsoprenalineA non-selective beta-adrenergic agonist typically used to treat bradycardia and heart block; it is structurally related to epinephrine.
DB01183NaloxoneAn opioid receptor antagonist used to rapidly reverse an opioid overdose. Also included in some drug formulations as an abuse deterrent to prevent injection.
DB00368NorepinephrineA sympathomimetic used in the control of blood pressure during various hypotensive states and as an adjunct treatment during cardiac arrest.
DrugDrug NameTargetType
DB00668EpinephrineAlpha-1A adrenergic receptortarget
DB00668EpinephrineBeta-1 adrenergic receptortarget
DB00668EpinephrineBeta-2 adrenergic receptortarget
DB00668EpinephrineSolute carrier family 22 member 2transporter
DB00668EpinephrineSolute carrier family 22 member 1transporter
DB00668EpinephrineCytochrome P450 2C9enzyme
DB00668EpinephrineCytochrome P450 3A4enzyme
DB00668EpinephrineAlpha-1B adrenergic receptortarget
DB00668EpinephrineAlpha-1D adrenergic receptortarget
DB00668EpinephrineAlpha-2A adrenergic receptortarget
DB00668EpinephrineAlpha-2B adrenergic receptortarget
DB00668EpinephrineTumor necrosis factortarget
DB00668EpinephrineCatechol O-methyltransferaseenzyme
DB00668EpinephrineMonoamine oxidaseenzyme
DB01064IsoprenalineBeta-1 adrenergic receptortarget
DB01064IsoprenalineBeta-2 adrenergic receptortarget
DB01064IsoprenalinePhosphatidylinositol 3-kinase regulatory subunit alphatarget
DB01064IsoprenalineBeta-3 adrenergic receptortarget
DB01064IsoprenalineMitogen-activated protein kinase 1target
DB01064IsoprenalinePhosphatidylinositol 3-kinase regulatory subunit betatarget
DB01064IsoprenalinePhosphatidylinositol 3-kinase regulatory subunit gammatarget
DB01064IsoprenalineCytochrome P450 1A1enzyme
DB01064IsoprenalineCAMP phosphodiesterasetarget
DB01064IsoprenalineSuperoxide dismutase [Cu-Zn]target
DB01183NaloxoneMu-type opioid receptortarget
DB01183NaloxoneEstrogen receptor alphatarget
DB01183NaloxoneCyclic AMP-responsive element-binding protein 1target
DB01183NaloxoneDelta-type opioid receptortarget
DB01183NaloxoneSolute carrier organic anion transporter family member 1A2transporter
DB01183NaloxoneP-glycoprotein 1transporter
DB01183NaloxoneKappa-type opioid receptortarget
DB01183NaloxoneCytochrome P450 3A4enzyme
DB01183NaloxoneSerum albumincarrier
DB01183NaloxoneToll-like receptor 4target
DB01183NaloxoneLiver carboxylesterase 1target
DB01183NaloxoneUDP-glucuronosyltransferase 1-1enzyme
DB00368NorepinephrinePhenylalanine-4-hydroxylasetarget
DB00368NorepinephrineAlpha-1A adrenergic receptortarget
DB00368NorepinephrineAlpha-1B adrenergic receptortarget
DB00368NorepinephrineAlpha-1D adrenergic receptortarget
DB00368NorepinephrineAlpha-2A adrenergic receptortarget
DB00368NorepinephrineAlpha-2B adrenergic receptortarget
DB00368NorepinephrineAlpha-2C adrenergic receptortarget
DB00368NorepinephrineBeta-1 adrenergic receptortarget
DB00368NorepinephrineBeta-2 adrenergic receptortarget
DB00368NorepinephrineBeta-3 adrenergic receptortarget
DB00368NorepinephrineSolute carrier family 22 member 2transporter
DB00368NorepinephrineSolute carrier family 22 member 3transporter
DB00368NorepinephrineSolute carrier family 22 member 5transporter
DB00368NorepinephrineSolute carrier family 22 member 1transporter
DB00368NorepinephrinePOU domain, class 5, transcription factor 1transporter
DB00368NorepinephrineSodium-dependent noradrenaline transportertransporter
DB00368NorepinephrineSynaptic vesicular amine transportertarget
DB00368NorepinephrineChromaffin granule amine transportertarget
DrugDrug NamePhaseStatusCount
DB11842Angiotensin II1Completed1
DB01914D-glucose1Withdrawn1
DB00583Levocarnitine1Terminated1
DB00435Nitric Oxide1Completed1
DB00152Thiamine1Withdrawn1
DB08842Acetylcarnitine1 / 2Completed1
DB11785Anisodamine1 / 2Recruiting1
DB00126Ascorbic acid1 / 2Completed1
DB00126Ascorbic acid1 / 2Recruiting1
DB01276Exenatide1 / 2Withdrawn1
DB13961Fish oil1 / 2Recruiting1
DB00741Hydrocortisone1 / 2Recruiting1
DB13959Medium-chain triglycerides1 / 2Recruiting1
DB00683Midazolam1 / 2Completed1
DB09567Olive oil1 / 2Recruiting1
DB01132Pioglitazone1 / 2Completed1
DB00818Propofol1 / 2Completed1
DB09422Soybean oil1 / 2Recruiting1
DB00152Thiamine1 / 2Completed1
DB11842Angiotensin II2Recruiting1
DB11842Angiotensin II2Unknown Status1
DB00126Ascorbic acid2Completed2
DB00126Ascorbic acid2Recruiting3
DB06779Dalteparin2Completed1
DB00633Dexmedetomidine2Recruiting1
DB00841Dobutamine2Completed1
DB12313Dopexamine2Completed1
DB00055Drotrecogin alfa2Completed1
DB00668Epinephrine2Completed1
DB00063Eptifibatide2Unknown Status1
DB04933Eritoran2Completed1
DB00187Esmolol2Completed2
DB00187Esmolol2Recruiting4
DB00687Fludrocortisone2Not Yet Recruiting1
DB01109Heparin2Completed1
DB01109Heparin2Recruiting1
DB00741Hydrocortisone2Completed2
DB00741Hydrocortisone2Not Yet Recruiting1
DB00741Hydrocortisone2Recruiting1
DB14541Hydrocortisone cypionate2Completed1
DB00200Hydroxocobalamin2Recruiting1
DB01088Iloprost2Unknown Status1
DB00583Levocarnitine2Completed1
DB00922Levosimendan2Completed1
DB09241Methylene blue2Not Yet Recruiting1
DB00683Midazolam2Recruiting1
DB00368Norepinephrine2Completed3
DB00388Phenylephrine2Completed2
DB00388Phenylephrine2Not Yet Recruiting1
DB13968Plasma protein fraction (human)2Active Not Recruiting1
DB11263Polydatin2Unknown Status1
DB00818Propofol2Not Yet Recruiting1
DB11312Protein C2Completed1
DB11127Selenious acid2Completed1
DB11135Selenium2Completed1
DB12495Selepressin2Completed2
DB01236Sevoflurane2Not Yet Recruiting1
DB09153Sodium chloride2Completed2
DB09153Sodium chloride2Recruiting1
DB02638Terlipressin2Completed1
DB02638Terlipressin2Unknown Status1
DB00152Thiamine2Completed2
DB00152Thiamine2Recruiting2
DB00302Tranexamic acid2Terminated1
DB00067Vasopressin2Completed1
DB09302Alirocumab2 / 3Not Yet Recruiting1
DB00126Ascorbic acid2 / 3Recruiting3
DB00575Clonidine2 / 3Terminated1
DB00841Dobutamine2 / 3Completed1
DB00841Dobutamine2 / 3Unknown Status1
DB00988Dopamine2 / 3Completed1
DB00187Esmolol2 / 3Recruiting1
DB00741Hydrocortisone2 / 3Recruiting2
DB01088Iloprost2 / 3Recruiting1
DB04398Lactic acid2 / 3Recruiting1
DB00922Levosimendan2 / 3Unknown Status1
DB00368Norepinephrine2 / 3Completed2
DB12495Selepressin2 / 3Terminated1
DB00641Simvastatin2 / 3Completed1
DB02638Terlipressin2 / 3Completed2
DB00152Thiamine2 / 3Recruiting2
DB00067Vasopressin2 / 3Completed2
DB06151Acetylcysteine3Recruiting1
DB01118Amiodarone3Not Yet Recruiting1
DB11842Angiotensin II3Suspended1
DB00126Ascorbic acid3Enrolling by Invitation1
DB00126Ascorbic acid3Recruiting4
DB01413Cefepime3Recruiting1
DB00493Cefotaxime3Recruiting1
DB01212Ceftriaxone3Recruiting1
DB00537Ciprofloxacin3Recruiting1
DB01211Clarithromycin3Completed1
DB00803Colistin3Recruiting1
DB01914D-glucose3Enrolling by Invitation1
DB00633Dexmedetomidine3Completed1
DB00633Dexmedetomidine3Recruiting2
DB09341Dextrose, unspecified form3Completed1
DB00988Dopamine3Completed1
DB00055Drotrecogin alfa3Completed1
DB00187Esmolol3Withdrawn1
DB00736Esomeprazole3Not Yet Recruiting1
DB09222Fibrinogen Human3Recruiting1
DB00687Fludrocortisone3Completed2
DB00687Fludrocortisone3Withdrawn1
DB00062Human Serum Albumin3Recruiting1
DB00741Hydrocortisone3Completed3
DB00741Hydrocortisone3Recruiting2
DB14545Hydrocortisone succinate3Completed1
DB14545Hydrocortisone succinate3Recruiting1
DB09106Hydroxyethyl Starch3Completed2
DB01050Ibuprofen3Completed1
DB00030Insulin human3Completed2
DB09083Ivabradine3Not Yet Recruiting1
DB01221Ketamine3Not Yet Recruiting1
DB01221Ketamine3Recruiting2
DB12465Ketanserin3Completed1
DB00583Levocarnitine3Recruiting1
DB00281Lidocaine3Not Yet Recruiting1
DB00281Lidocaine3Recruiting1
DB01065Melatonin3Recruiting1
DB01065Melatonin3Unknown Status1
DB00760Meropenem3Completed1
DB00760Meropenem3Recruiting1
DB09241Methylene blue3Recruiting2
DB00683Midazolam3Not Yet Recruiting1
DB00683Midazolam3Recruiting1
DB00211Midodrine3Recruiting1
DB00211Midodrine3Terminated1
DB00218Moxifloxacin3Completed1
DB00727Nitroglycerin3Completed1
DB00368Norepinephrine3Completed2
DB00368Norepinephrine3Suspended1
DB00368Norepinephrine3Terminated1
DB00646Nystatin3Recruiting1
DB00319Piperacillin3Recruiting1
DB00020Sargramostim3Completed1
DB11127Selenious acid3Completed1
DB01606Tazobactam3Recruiting1
DB02638Terlipressin3Recruiting1
DB02638Terlipressin3Terminated1
DB00152Thiamine3Enrolling by Invitation1
DB00152Thiamine3Recruiting2
DB00599Thiopental3Recruiting1
DB00684Tobramycin3Recruiting1
DB00302Tranexamic acid3Recruiting1
DB00067Vasopressin3Completed1
DB00163Vitamin E3Recruiting1
DB01118Amiodarone4Recruiting1
DB01118Amiodarone4Terminated1
DB00126Ascorbic acid4Not Yet Recruiting1
DB00126Ascorbic acid4Terminated1
DB00520Caspofungin4Completed1
DB01212Ceftriaxone4Unknown Status1
DB00633Dexmedetomidine4Completed1
DB00633Dexmedetomidine4Recruiting2
DB00055Drotrecogin alfa4Completed2
DB00813Fentanyl4Completed1
DB00813Fentanyl4Recruiting1
DB00741Hydrocortisone4Completed1
DB00741Hydrocortisone4Not Yet Recruiting1
DB00741Hydrocortisone4Terminated3
DB14545Hydrocortisone succinate4Completed2
DB09106Hydroxyethyl Starch4Completed1
DB01221Ketamine4Recruiting1
DB00922Levosimendan4Recruiting1
DB09241Methylene blue4Completed1
DB00959Methylprednisolone4Terminated1
DB01141Micafungin4Completed1
DB00683Midazolam4Completed1
DB00683Midazolam4Recruiting1
DB00211Midodrine4Recruiting1
DB00211Midodrine4Withdrawn1
DB00235Milrinone4Recruiting1
DB00368Norepinephrine4Completed2
DB00368Norepinephrine4Recruiting1
DB00368Norepinephrine4Terminated1
DB00368Norepinephrine4Withdrawn1
DB00388Phenylephrine4Completed1
DB00388Phenylephrine4Terminated1
DB00319Piperacillin4Terminated1
DB00635Prednisone4Terminated1
DB01182Propafenone4Recruiting1
DB00818Propofol4Completed1
DB00728Rocuronium4Completed1
DB00641Simvastatin4Unknown Status1
DB09153Sodium chloride4Terminated1
DB01606Tazobactam4Terminated1
DB02638Terlipressin4Recruiting1
DB00152Thiamine4Not Yet Recruiting1
DB00152Thiamine4Terminated1
DB11237Trypsin4Recruiting1
DB12038Ulinastatin4Recruiting1
DB00067Vasopressin4Withdrawn1
DB04630AldosteroneNot AvailableRecruiting1
DB00479AmikacinNot AvailableNot Yet Recruiting1
DB00126Ascorbic acidNot AvailableActive Not Recruiting1
DB01076AtorvastatinNot AvailableCompleted1
DB00112BevacizumabNot AvailableWithdrawn1
DB00520CaspofunginNot AvailableNot Yet Recruiting1
DB01212CeftriaxoneNot AvailableCompleted1
DB01285CorticotropinNot AvailableCompleted1
DB00080DaptomycinNot AvailableRecruiting1
DB00841DobutamineNot AvailableCompleted1
DB00841DobutamineNot AvailableRecruiting1
DB00988DopamineNot AvailableRecruiting1
DB06211DoripenemNot AvailableCompleted1
DB00668EpinephrineNot AvailableRecruiting1
DB00187EsmololNot AvailableCompleted1
DB01109HeparinNot AvailableUnknown Status1
DB00741HydrocortisoneNot AvailableCompleted1
DB00741HydrocortisoneNot AvailableRecruiting2
DB09106Hydroxyethyl StarchNot AvailableCompleted1
DB01598ImipenemNot AvailableRecruiting1
DB04398Lactic acidNot AvailableCompleted1
DB00922LevosimendanNot AvailableRecruiting2
DB00653Magnesium sulfateNot AvailableCompleted1
DB00760MeropenemNot AvailableCompleted1
DB00368NorepinephrineNot AvailableCompleted2
DB00368NorepinephrineNot AvailableRecruiting1
DB00368NorepinephrineNot AvailableTerminated1
DB00368NorepinephrineNot AvailableUnknown Status2
DB00981PhysostigmineNot AvailableCompleted1
DB00319PiperacillinNot AvailableCompleted1
DB00319PiperacillinNot AvailableNot Yet Recruiting1
DB00899RemifentanilNot AvailableRecruiting1
DB01606TazobactamNot AvailableCompleted1
DB01606TazobactamNot AvailableNot Yet Recruiting1
DB02638TerlipressinNot AvailableUnknown Status2
DB00067VasopressinNot AvailableCompleted1
DB00067VasopressinNot AvailableTerminated1